Details for: CHP1

Gene ID: 11261

Symbol: CHP1

Ensembl ID: ENSG00000187446

Description: calcineurin like EF-hand protein 1

Associated with

Other Information

Genular Protein ID: 2001420919

Symbol: CHP1_HUMAN

Name: Calcineurin B homologous protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8901634

Title: A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

PubMed ID: 8901634

DOI: 10.1073/pnas.93.22.12631

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10593895

Title: Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein.

PubMed ID: 10593895

DOI: 10.1074/jbc.274.51.36125

PubMed ID: 11350981

Title: Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers.

PubMed ID: 11350981

DOI: 10.1074/jbc.m100296200

PubMed ID: 15035633

Title: Role of calcineurin B homologous protein in pH regulation by the Na+/H+ exchanger 1: tightly bound Ca2+ ions as important structural elements.

PubMed ID: 15035633

DOI: 10.1021/bi0360004

PubMed ID: 20720019

Title: Nuclear-localized calcineurin homologous protein CHP1 interacts with upstream binding factor and inhibits ribosomal RNA synthesis.

PubMed ID: 20720019

DOI: 10.1074/jbc.m110.165555

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25255805

Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.

PubMed ID: 25255805

DOI: 10.1038/ncomms5919

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 17050540

Title: Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homologous protein 1.

PubMed ID: 17050540

DOI: 10.1074/jbc.m604092200

PubMed ID: 29379881

Title: Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.

PubMed ID: 29379881

DOI: 10.1212/nxg.0000000000000209

PubMed ID: 34108458

Title: Structure and mechanism of the human NHE1-CHP1 complex.

PubMed ID: 34108458

DOI: 10.1038/s41467-021-23496-z

PubMed ID: 35613257

Title: Structural basis of autoinhibition of the human NHE3-CHP1 complex.

PubMed ID: 35613257

DOI: 10.1126/sciadv.abn3925

Sequence Information:

  • Length: 195
  • Mass: 22456
  • Checksum: 8E82EEF0CA5E832F
  • Sequence:
  • MGSRASTLLR DEELEEIKKE TGFSHSQITR LYSRFTSLDK GENGTLSRED FQRIPELAIN 
    PLGDRIINAF FPEGEDQVNF RGFMRTLAHF RPIEDNEKSK DVNGPEPLNS RSNKLHFAFR 
    LYDLDKDEKI SRDELLQVLR MMVGVNISDE QLGSIADRTI QEADQDGDSA ISFTEFVKVL 
    EKVDVEQKMS IRFLH

Genular Protein ID: 793548997

Symbol: H0YKE7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 123
  • Mass: 14270
  • Checksum: F60288C34D41162B
  • Sequence:
  • MGSRASTLLR DEELEEIKKE TGFSHSQITR LYSRFTSLDK GENGTLSRED FQRIPELAIN 
    PLGDRIINAF FPEGEDQVNF RGFMRTLAHF RPIEDNEKSK DVNGPEPLNS RSNKLHLEEE 
    RYI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.