Details for: SP140

Gene ID: 11262

Symbol: SP140

Ensembl ID: ENSG00000079263

Description: SP140 nuclear body protein

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.51
    Marker Score: 4,371
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.04
    Marker Score: 1,916
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.74
    Marker Score: 1,048
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 1.72
    Marker Score: 396
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.65
    Marker Score: 585
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6
    Marker Score: 4,745
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.58
    Marker Score: 1,149
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.57
    Marker Score: 3,299
  • Cell Name: centroblast (CL0009112)
    Fold Change: 1.55
    Marker Score: 762
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.51
    Marker Score: 1,145
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.43
    Marker Score: 14,179
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.41
    Marker Score: 1,405
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.38
    Marker Score: 1,363
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 1.31
    Marker Score: 362
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.29
    Marker Score: 1,154
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 1.29
    Marker Score: 786
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.24
    Marker Score: 837
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.22
    Marker Score: 7,794
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 1.22
    Marker Score: 320
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.17
    Marker Score: 3,683
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.16
    Marker Score: 479
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4,770
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 1.13
    Marker Score: 269
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 1.11
    Marker Score: 387
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.08
    Marker Score: 1,440
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.06
    Marker Score: 12,328
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.05
    Marker Score: 2,948
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.05
    Marker Score: 604
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 1
    Marker Score: 732
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,767
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,991
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.99
    Marker Score: 1,876
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,402
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 500
  • Cell Name: B-1a B cell (CL0000820)
    Fold Change: 0.97
    Marker Score: 232
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.97
    Marker Score: 851
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.97
    Marker Score: 567
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 455
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.95
    Marker Score: 892
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.95
    Marker Score: 301
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,408
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.94
    Marker Score: 430
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.93
    Marker Score: 556
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.92
    Marker Score: 777
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 369
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.92
    Marker Score: 872
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,734
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.91
    Marker Score: 47,897
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.9
    Marker Score: 446
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 321
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.88
    Marker Score: 1,290
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4,964
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,267
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.86
    Marker Score: 677
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.84
    Marker Score: 644
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 0.84
    Marker Score: 2,318
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.81
    Marker Score: 3,490
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 0.79
    Marker Score: 581
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 0.79
    Marker Score: 572
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.77
    Marker Score: 1,247
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.77
    Marker Score: 856
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 0.77
    Marker Score: 1,868
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 0.77
    Marker Score: 681
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.76
    Marker Score: 555
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 390
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.74
    Marker Score: 457
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.74
    Marker Score: 675
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 0.74
    Marker Score: 487
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.73
    Marker Score: 317
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.73
    Marker Score: 227
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 0.73
    Marker Score: 427
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 0.72
    Marker Score: 522
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.72
    Marker Score: 1,462
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.72
    Marker Score: 775
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.71
    Marker Score: 229
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.71
    Marker Score: 603
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.71
    Marker Score: 454
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.7
    Marker Score: 160
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.7
    Marker Score: 907
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.68
    Marker Score: 246
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.68
    Marker Score: 339
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.67
    Marker Score: 651
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.66
    Marker Score: 332
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.65
    Marker Score: 198
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 0.65
    Marker Score: 1,888
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 0.63
    Marker Score: 702
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 0.63
    Marker Score: 325
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: 0.63
    Marker Score: 415
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.63
    Marker Score: 1,232
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 0.62
    Marker Score: 218
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 0.61
    Marker Score: 1,044
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 0.61
    Marker Score: 536
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.61
    Marker Score: 1,574
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 0.6
    Marker Score: 199
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 0.6
    Marker Score: 655
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.6
    Marker Score: 259
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 0.59
    Marker Score: 481
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.59
    Marker Score: 597
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.58
    Marker Score: 1,311

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SP140 is a nuclear body protein, which implies its involvement in the regulation of gene expression within the nucleoplasm. Its expression is predominantly restricted to immune cells, including B cells, suggesting a specialized role in the immune system. Notably, SP140 is associated with Pml bodies, fibrillar centers, and metal ion binding, which further underscores its multifaceted nature. Its ability to bind to DNA and RNA polymerase II-specific regulation positions SP140 as a critical regulator of transcriptional activity. **Pathways and Functions:** SP140's involvement in the following pathways highlights its significance in immune cell function: 1. **Defense response:** SP140's expression in immune cells and its association with DNA-binding transcription factor activity suggest a role in modulating the immune response to pathogens. 2. **DNA-binding transcription factor activity:** SP140's ability to bind to DNA and RNA polymerase II-specific regulation implies its involvement in the regulation of gene expression, potentially influencing the production of cytokines and other immune-related molecules. 3. **RNA polymerase II-specific regulation:** This pathway highlights SP140's role in regulating transcriptional activity, which is critical for the proper functioning of immune cells. 4. **Metal ion binding:** SP140's association with metal ion binding suggests a potential role in the regulation of redox reactions, which are essential for immune cell function. **Clinical Significance:** The clinical significance of SP140 lies in its potential role in the regulation of immune responses. Dysregulation of SP140 expression or function may contribute to the development of autoimmune disorders, such as rheumatoid arthritis or lupus. Furthermore, SP140's involvement in the regulation of transcriptional activity suggests its potential as a therapeutic target in the treatment of immune-related diseases. In conclusion, SP140 is a multifaceted nuclear body protein that plays a critical role in the regulation of immune responses. Its involvement in DNA-binding transcription factor activity, RNA polymerase II-specific regulation, and its association with Pml bodies and fibrillar centers positions SP140 as a key regulator of transcriptional activity. Further research is necessary to elucidate the precise mechanisms by which SP140 regulates immune responses and to explore its potential as a therapeutic target in the treatment of immune-related diseases.

Genular Protein ID: 204678511

Symbol: SP140_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q13342 E7ESH9 E7EUR5 E9PFJ6 Q0VGE5 Q13341 Q3KR17 Q4ZG66 Q53TG1 Q6NSG4 Q92881 Q96TG3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 5 ExpressionAtlas 1 GO 9 Gene3D 3 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PIR 1 PRO 1 PROSITE 5 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 RNAct 1 RefSeq 5 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8695863

Title: LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.

PubMed ID: 8695863

PubMed ID: 8910577

Title: Identification and characterization of a leukocyte-specific component of the nuclear body.

PubMed ID: 8910577

DOI: 10.1074/jbc.271.46.29198

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24267382

Title: Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1.

PubMed ID: 24267382

DOI: 10.1111/febs.12588

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

Sequence Information:

  • Length: 867
  • Mass: 98223
  • Checksum: 355601D1D4689A74
  • Sequence:
    • MAQQGQQGQM ASGDSNLNFR MVAEIQNVEG QNLQEQVCPE PIFRFFRENK VEIASAITRP 
FPFLMGLRDR SFISEQMYEH FQEAFRNLVP VTRVMYCVLS ELEKTFGWSH LEALFSRINL 
MAYPDLNEIY RSFQNVCYEH SPLQMNNVND LEDRPRLLPY GKQENSNACH EMDDIAVPQE 
ALSSSPRCEP GFSSESCEQL ALPKAGGGDA EDAPSLLPGG GVSCKLAIQI DEGESEEMPK 
LLPYDTEVLE SNGMIDAART YSTAPGEKQG EEEGRNSPRK RNQDKEKYQE SPEGRDKETF 
DLKTPQVTNE GEPEKGLCLL PGEGEEGSDD CSEMCDGEEP QEASSSLARC GSVSCLSAET 
FDLKTPQVTN EGEPEKELSL LPGEGEEGSD DCSEMCDGEE RQEASSSLAR RGSVSSELEN 
HPMNEEGESE ELASSLLYDN VPGAEQSAYE NEKCSCVMCF SEEVPGSPEA RTESDQACGT 
MDTVDIANNS TLGKPKRKRR KKRGHGWSRM RMRRQENSQQ NDNSKADGQV VSSEKKANVN 
LKDLSKIRGR KRGKPGTRFT QSDRAAQKRV RSRASRKHKD ETVDFKAPLL PVTCGGVKGI 
LHKKKLQQGI LVKCIQTEDG KWFTPTEFEI KGGHARSKNW RLSVRCGGWP LRWLMENGFL 
PDPPRIRYRK KKRILKSQNN SSVDPCMRNL DECEVCRDGG ELFCCDTCSR VFHEDCHIPP 
VEAERTPWNC IFCRMKESPG SQQCCQESEV LERQMCPEEQ LKCEFLLLKV YCCSESSFFA 
KIPYYYYIRE ACQGLKEPMW LDKIKKRLNE HGYPQVEGFV QDMRLIFQNH RASYKYKDFG 
QMGFRLEAEF EKNFKEVFAI QETNGNN

Genular Protein ID: 2636195346

Symbol: Q8IWJ1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IWJ1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Genevisible 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 283
  • Mass: 31829
  • Checksum: D20318B1B26F6FE5
  • Sequence:
    • MAQQGQQGQM ASGDSNLNFR MVAEIQNVEG QNLQEQVCPE PIFRFFRENK VEIASAITRP 
FPFLMGLRDR SFISEQMYEH FQEAFRNLVP VTRVMYCVLS ELEKTFGWSH LEALFSRINL 
MAYPDLNEIY RSFQNVCYEH SPLQMNNVND LEDRPRLLPY GKQENSNACH EMDDIAVPQE 
ALSSSPRCEP GFSSESCEQL ALPKAGGGDA EDAPSLLPGG GVSCKLAIQI DEGESEEMPK 
LLPYDTEVLE SNGMIDAART YSTAPGEKQG EEEGRNSPRK KKK

Genular Protein ID: 1197259883

Symbol: B4DVW8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DVW8

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 11 KEGG 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 2 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 768
  • Mass: 86713
  • Checksum: 9DF44ACF60B87825
  • Sequence:
    • MAQQGQQGQM ASGDSNLNFR MVAEIQNVEG QNLQEQVCPE PIFRFFRENK VEIASAITRP 
FPFLMGLRDR SFISEQMYEH FQEAFRNLVP VTRVMYCVLS ELEKTFGWSH LEALFSRINL 
MAYPDLNEIY RSFQNVCYEH SPLQMNNVND LEDRPRLLPY GKQENSNACH EMDDIAVPQG 
ALSSSPRCEP GFSSESCEQL ALPKAGGGDA EDAPSLLPGG GETFDLKTPQ VTNEGEPEKG 
LCLLPGEGEE GSDDCSEMCD GEEPQEASSS LAGCGSVSCL SAETFDLKTP QVTNEGEPEK 
ELSLLPGEGE EGSDDCSEMC DGEERQEASS SLARRGSVSS ELENHPMNEE GESEELASSL 
LYDNVPGAEQ SAYENEKCSC VMCFSEEVPG SPEARTESDQ ACGTMDTVDI ANNSTLGKPK 
RERRKKRGHG WSRMRMRRQK NSQQNDNSKA DGQVVSSEKK ANVNLKDLSK IRGRKRGKPG 
TRFTQSDRAA QKRVRSRASR KHKDETVDFK APLLPVTCGG VKGILHKKRL QQGILVKCIQ 
TEDGKWFTPT EFEIKGGHAR SKNWRLSVRC GGWPLRWLME NGFLPDPPRI RYRKKKRILK 
SQNNSSVDPC MRNLDECEVC RDGGELFCCD TCSRVFHEDC HIPPVEAERT PWNCIFCRMK 
ESPGSQQCCQ ESEVLERQMR PEEQLKCEFL LLKVYCCSES SFFAKIPYYY YIREACQGLK 
EPMWLDKIKK RLNEHGYPQV EGFVQDMRLI FQNHRASYKA VHGRPGCR

Genular Protein ID: 3913628455

Symbol: Q0VGE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q0VGE4

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 3 GenomeRNAi 1 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 807
  • Mass: 91672
  • Checksum: 39E12EAF9F20362C
  • Sequence:
    • MAQQGQQGQM ASGDSNLNFR MVAEIQNVEG QNLQEQVCPE PIFRFFRENK VEIASAITRP 
FPFLMGLRDR SFISEQMYEH FQEAFRNLVP VTRVMYCVLS ELEKTFGWSH LEALFSRINL 
MAYPDLNEIY RSFQNVCYEH SPLQMNNVND LEDRPRLLPY GKQENSNACH EMDDIAVPQE 
ALSSSPRCEP GFSSESCEQL ALPKAGGGDA EDAPSLLPGG GVLESNGMID AARTYSTAPG 
EKQGEEEGRN SPRKRNQDKE KYQESPEGRD KETFDLKTPQ VTNEGEPEKG LCLLPGEGEE 
GSDDCSEMCD GEEPQEASSS LARCGSEGSD DCSEMCDGEE RQEASSSLAR RGSVSSELEN 
HPMNEEGESE ELASSLLYDN VPGAEQSAYE NEKCSCVMCF SEEVPGSPEA RTESDQACGT 
MDTVDIANNS TLGKPKRKRR KKRGHGWSRM RMRRQKNSQQ NDNSKADGQV VSSEKKANVN 
LKDLSKIRGR KRGKPGTRFT QSDRAAQKRV RSRASRKHKD ETVDFKAPLL PVTCGGVKGI 
LHKKKLQQGI LVKCIQTEDG KWFTPTEFEI KGGHARSKNW RLSVRCGGWP LRWLMENGFL 
PDPPRIRYRK KKRILKSQNN SSVDPCMRNL DECEVCRDGG ELFCCDTCSR VFHEDCHIPP 
VEAERTPWNC IFCRMKESPG SQQCCQESEV LERQMCPEEQ LKCEFLLLKV YCCSESSFFA 
KIPYYYYIRE ACQGLKEPMW LDKIKKRLNE HGYPQVEGFV QDMRLIFQNH RASYKYKDFG 
QMGFRLEAEF EKNFKEVFAI QETNGNN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.