SNF8 | ENSG00000159210 | NCBI 11267

Details for: SNF8

Gene ID: 11267

Symbol: SNF8

Ensembl ID: ENSG00000159210

Description: SNF8 subunit of ESCRT-II

Associated with

Disease
(R-HSA-1643685)
Endosomal sorting complex required for transport (escrt)
(R-HSA-917729)
Hcmv infection
(R-HSA-9609646)
Hcmv late events
(R-HSA-9610379)
Infectious disease
(R-HSA-5663205)
Membrane trafficking
(R-HSA-199991)
Vesicle-mediated transport
(R-HSA-5653656)
Viral infection pathways
(R-HSA-9824446)
Channel regulator activity
(GO:0016247)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Early endosome to late endosome transport
(GO:0045022)
Endocytic recycling
(GO:0032456)
Endosome membrane
(GO:0010008)
Escrt ii complex
(GO:0000814)
Extracellular exosome
(GO:0070062)
Late endosome membrane
(GO:0031902)
Lipid binding
(GO:0008289)
Localization
(GO:0051179)
Macroautophagy
(GO:0016236)
Membrane
(GO:0016020)
Membrane fission
(GO:0090148)
Multivesicular body assembly
(GO:0036258)
Multivesicular body sorting pathway
(GO:0071985)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of exosomal secretion
(GO:1903543)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of protein catabolic process
(GO:0045732)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
(GO:0043328)
Recycling endosome
(GO:0055037)
Regulation of map kinase activity
(GO:0043405)
Regulation of protein catabolic process
(GO:0042176)
Regulation of protein complex stability
(GO:0061635)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Vacuolar-sorting protein SNF8

Genular Protein ID: 657588429

Symbol: SNF8_HUMAN

Name: Vacuolar-sorting protein SNF8

UniProtKB Accession Codes:

Q96H20 Q8IXY3 Q9UN50

Database IDs:

Citations:

PubMed ID: 10419521

Title: Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II.

PubMed ID: 10419521

DOI: 10.1074/jbc.274.31.21981

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14505570

Title: The protein network of HIV budding.

PubMed ID: 14505570

DOI: 10.1016/s0092-8674(03)00714-1

PubMed ID: 14519844

Title: Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins.

PubMed ID: 14519844

DOI: 10.1073/pnas.2133846100

PubMed ID: 16857164

Title: RILP interacts with the VPS22 component of the ESCRT-II complex.

PubMed ID: 16857164

DOI: 10.1016/j.bbrc.2006.07.007

PubMed ID: 17010938

Title: RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment.

PubMed ID: 17010938

DOI: 10.1016/j.bbrc.2006.09.064

PubMed ID: 16260042

Title: Rapid identification of 14-3-3-binding proteins by protein microarray analysis.

PubMed ID: 16260042

DOI: 10.1016/j.jneumeth.2005.09.015

PubMed ID: 16973552

Title: Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.

PubMed ID: 16973552

DOI: 10.1128/jvi.01049-06

PubMed ID: 17959629

Title: RILP is required for the proper morphology and function of late endosomes.

PubMed ID: 17959629

DOI: 10.1242/jcs.017301

PubMed ID: 17714434

Title: Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation.

PubMed ID: 17714434

DOI: 10.1111/j.1600-0854.2007.00630.x

PubMed ID: 18031739

Title: Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking.

PubMed ID: 18031739

DOI: 10.1016/j.yexcr.2007.10.014

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22660413

Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.

PubMed ID: 22660413

DOI: 10.1038/ncb2502

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 18539118

Title: Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex.

PubMed ID: 18539118

DOI: 10.1016/j.devcel.2008.04.004

Sequence Information:

Length: 258
Mass: 28864
Checksum: FD6CBA6BC0A4485E
Sequence:

MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF ASKHKQEIRK 
NPEFRVQFQD MCATIGVDPL ASGKGFWSEM LGVGDFYYEL GVQIIEVCLA LKHRNGGLIT 
LEELHQQVLK GRGKFAQDVS QDDLIRAIKK LKALGTGFGI IPVGGTYLIQ SVPAELNMDH 
TVVLQLAEKN GYVTVSEIKA SLKWETERAR QVLEHLLKEG LAWLDLQAPG EAHYWLPALF 
TDLYSQEITA EEAREALP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SNF8

Associated with

Other Information

Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II. PubMed ID: 10419521

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The protein network of HIV budding. PubMed ID: 14505570

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. PubMed ID: 14519844

RILP interacts with the VPS22 component of the ESCRT-II complex. PubMed ID: 16857164

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment. PubMed ID: 17010938

Rapid identification of 14-3-3-binding proteins by protein microarray analysis. PubMed ID: 16260042

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. PubMed ID: 16973552

RILP is required for the proper morphology and function of late endosomes. PubMed ID: 17959629

Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation. PubMed ID: 17714434

Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking. PubMed ID: 18031739

Initial characterization of the human central proteome. PubMed ID: 21269460

Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. PubMed ID: 22660413

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. PubMed ID: 18539118