Details for: KLHL2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.61
Marker Score: 7,444 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.19
Marker Score: 2,421 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.86
Marker Score: 3,128 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.83
Marker Score: 17,199 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.82
Marker Score: 17,273 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.79
Marker Score: 110,163 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.75
Marker Score: 14,993 - Cell Name: neuron (CL0000540)
Fold Change: 1.63
Marker Score: 6,641 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.56
Marker Score: 934 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.49
Marker Score: 2,295 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,397 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.43
Marker Score: 5,535 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.4
Marker Score: 14,489 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.31
Marker Score: 1,010 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.3
Marker Score: 1,892 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.25
Marker Score: 2,994 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.15
Marker Score: 2,343 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.14
Marker Score: 43,334 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.1
Marker Score: 7,081 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.09
Marker Score: 1,171 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.09
Marker Score: 340 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.06
Marker Score: 4,567 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.06
Marker Score: 937 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.06
Marker Score: 38,953 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.05
Marker Score: 22,499 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.04
Marker Score: 354 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,749 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,974 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.97
Marker Score: 2,221 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.97
Marker Score: 1,050 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,405 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 487 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 442 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.92
Marker Score: 14,842 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.91
Marker Score: 294 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,721 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.9
Marker Score: 4,862 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.89
Marker Score: 6,820 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.89
Marker Score: 1,023 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5,010 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.87
Marker Score: 985 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 312 - Cell Name: germ cell (CL0000586)
Fold Change: 0.85
Marker Score: 1,480 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.83
Marker Score: 1,954 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.82
Marker Score: 297 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.8
Marker Score: 421 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.79
Marker Score: 3,317 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.78
Marker Score: 545 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 599 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.78
Marker Score: 387 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.78
Marker Score: 1,106 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 313 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.78
Marker Score: 3,259 - Cell Name: lung macrophage (CL1001603)
Fold Change: 0.77
Marker Score: 884 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.77
Marker Score: 1,485 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,247 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.77
Marker Score: 2,971 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.74
Marker Score: 204 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.73
Marker Score: 3,399 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.73
Marker Score: 3,608 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 379 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.73
Marker Score: 272 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.71
Marker Score: 206 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.71
Marker Score: 14,197 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.71
Marker Score: 11,098 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.69
Marker Score: 462 - Cell Name: brush cell (CL0002204)
Fold Change: 0.69
Marker Score: 629 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.68
Marker Score: 588 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.68
Marker Score: 337 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.68
Marker Score: 685 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 172 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.67
Marker Score: 135 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.66
Marker Score: 1,603 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.66
Marker Score: 4,308 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.66
Marker Score: 383 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.65
Marker Score: 381 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.63
Marker Score: 230 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.63
Marker Score: 16,193 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.63
Marker Score: 237 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.63
Marker Score: 661 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.63
Marker Score: 1,145 - Cell Name: podocyte (CL0000653)
Fold Change: 0.62
Marker Score: 230 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.62
Marker Score: 423 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.62
Marker Score: 216 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.62
Marker Score: 9,201 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.61
Marker Score: 2,528 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.61
Marker Score: 175 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.6
Marker Score: 1,481 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.59
Marker Score: 288 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.59
Marker Score: 2,472 - Cell Name: club cell (CL0000158)
Fold Change: 0.59
Marker Score: 689 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.59
Marker Score: 941 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.58
Marker Score: 19,511 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.58
Marker Score: 234 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.57
Marker Score: 344 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.56
Marker Score: 1,415 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.56
Marker Score: 134 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.56
Marker Score: 499
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 303898499
Symbol: KLHL2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10397770
Title: Characterization of Mayven, a novel actin-binding protein predominantly expressed in brain.
PubMed ID: 10397770
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15383316
Title: hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure.
PubMed ID: 15383316
PubMed ID: 15715669
Title: Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven.
PubMed ID: 15715669
PubMed ID: 23838290
Title: KLHL2 interacts with and ubiquitinates WNK kinases.
PubMed ID: 23838290
PubMed ID: 23349464
Title: Structural basis for Cul3 assembly with the BTB-Kelch family of E3 ubiquitin ligases.
PubMed ID: 23349464
PubMed ID: 24641320
Title: Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.
PubMed ID: 24641320
DOI: 10.1042/bj20140153
Sequence Information:
- Length: 593
- Mass: 65975
- Checksum: 397AE02E69E56A18
- Sequence:
METPPLPPAC TKQGHQKPLD SKDDNTEKHC PVTVNPWHMK KAFKVMNELR SQNLLCDVTI VAEDMEISAH RVVLAACSPY FHAMFTGEMS ESRAKRVRIK EVDGWTLRML IDYVYTAEIQ VTEENVQVLL PAAGLLQLQD VKKTCCEFLE SQLHPVNCLG IRAFADMHAC TDLLNKANTY AEQHFADVVL SEEFLNLGIE QVCSLISSDK LTISSEEKVF EAVIAWVNHD KDVRQEFMAR LMEHVRLPLL PREYLVQRVE EEALVKNSSA CKDYLIEAMK YHLLPTEQRI LMKSVRTRLR TPMNLPKLMV VVGGQAPKAI RSVECYDFKE ERWHQVAELP SRRCRAGMVY MAGLVFAVGG FNGSLRVRTV DSYDPVKDQW TSVANMRDRR STLGAAVLNG LLYAVGGFDG STGLSSVEAY NIKSNEWFHV APMNTRRSSV GVGVVGGLLY AVGGYDGASR QCLSTVECYN ATTNEWTYIA EMSTRRSGAG VGVLNNLLYA VGGHDGPLVR KSVEVYDPTT NAWRQVADMN MCRRNAGVCA VNGLLYVVGG DDGSCNLASV EYYNPTTDKW TVVSSCMSTG RSYAGVTVID KPL
Genular Protein ID: 1003489269
Symbol: B4DFZ5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 427
- Mass: 47209
- Checksum: 03115FAF2293BB42
- Sequence:
MHACTDLLNK ANTYAEQHFA DVVLSEEFLN LGIEQVCSLI SSDKLTISSE EKVFEAVIAW VNHDKDVRQE FMARLMEHVR LPLLPREYLV QRVEEEALVK NSSACKDYLI EAMKYHLLPT EQRILMKSVR TRLRTPMNLP KLMVVVGGQA PKAIRSVECY DFKEERWHQV AELPSRRCRA GMVYMAGLVF AVGGFNGSLR VRTVDSYDPV KDQWTSVANM RDRRSTLGAA VLNGLLYAVG GFDGSTGLSS VEAYNIKSNE WFHVAPMNTR RSSVGVGVVG GLLYAVGGYD GASRQCLSTV ECYNATTNEW TYIAEMSTRR SGAGVGVLNN LLYAVGGHDG PLVRKSVEVY DPTTNAWRQV ADMNMCRRNA GVCAVNGLLY VVGGDDGSCN LASVEYYNPT TDKWTVVSSC MSTGRSYAGV TVIDKPL
Genular Protein ID: 1197820856
Symbol: E9PEX9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 496
- Mass: 55194
- Checksum: 000B50F03119AEAF
- Sequence:
MSQLWQKTWK FLLIEWCWPP VVLIFMPCLQ VLLPAAGLLQ LQDVKKTCCE FLESQLHPVN CLGIRAFADM HACTDLLNKA NTYAEQHFAD VVLSEEFLNL GIEQVCSLIS SDKLTISSEE KVFEAVIAWV NHDKDVRQEF MARLMEHVRL PLLPREYLVQ RVEEEALVKN SSACKDYLIE AMKYHLLPTE QRILMKSVRT RLRTPMNLPK LMVVVGGQAP KAIRSVECYD FKEERWHQVA ELPSRRCRAG MVYMAGLVFA VGGFNGSLRV RTVDSYDPVK DQWTSVANMR DRRSTLGAAV LNGLLYAVGG FDGSTGLSSV EAYNIKSNEW FHVAPMNTRR SSVGVGVVGG LLYAVGGYDG ASRQCLSTVE CYNATTNEWT YIAEMSTRRS GAGVGVLNNL LYAVGGHDGP LVRKSVEVYD PTTNAWRQVA DMNMCRRNAG VCAVNGLLYV VGGDDGSCNL ASVEYYNPTT DKWTVVSSCM STGRSYAGVT VIDKPL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.