Details for: CHRM2

Gene ID: 1129

Symbol: CHRM2

Ensembl ID: ENSG00000181072

Description: cholinergic receptor muscarinic 2

Associated with

Other Information

Genular Protein ID: 3053406946

Symbol: ACM2_HUMAN

Name: Muscarinic acetylcholine receptor M2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3037705

Title: Identification of a family of muscarinic acetylcholine receptor genes.

PubMed ID: 3037705

DOI: 10.1126/science.3037705

PubMed ID: 3443095

Title: Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

PubMed ID: 3443095

DOI: 10.1002/j.1460-2075.1987.tb02733.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15014171

Title: Human-specific amino acid changes found in 103 protein-coding genes.

PubMed ID: 15014171

DOI: 10.1093/molbev/msh100

PubMed ID: 7822302

Title: Arrestin interactions with G protein-coupled receptors. Direct binding studies of wild type and mutant arrestins with rhodopsin, beta 2-adrenergic, and m2 muscarinic cholinergic receptors.

PubMed ID: 7822302

DOI: 10.1074/jbc.270.2.720

PubMed ID: 16548883

Title: Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

PubMed ID: 16548883

DOI: 10.1111/j.1462-5822.2005.00644.x

PubMed ID: 15229186

Title: Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.

PubMed ID: 15229186

DOI: 10.1093/hmg/ddh194

PubMed ID: 20976005

Title: RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking.

PubMed ID: 20976005

DOI: 10.1371/journal.pone.0013517

PubMed ID: 22278061

Title: Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.

PubMed ID: 22278061

DOI: 10.1038/nature10753

PubMed ID: 24256733

Title: Activation and allosteric modulation of a muscarinic acetylcholine receptor.

PubMed ID: 24256733

DOI: 10.1038/nature12735

Sequence Information:

  • Length: 466
  • Mass: 51715
  • Checksum: 2FC2FD7748C22BEC
  • Sequence:
  • MNNSTNSSNN SLALTSPYKT FEVVFIVLVA GSLSLVTIIG NILVMVSIKV NRHLQTVNNY 
    FLFSLACADL IIGVFSMNLY TLYTVIGYWP LGPVVCDLWL ALDYVVSNAS VMNLLIISFD 
    RYFCVTKPLT YPVKRTTKMA GMMIAAAWVL SFILWAPAIL FWQFIVGVRT VEDGECYIQF 
    FSNAAVTFGT AIAAFYLPVI IMTVLYWHIS RASKSRIKKD KKEPVANQDP VSPSLVQGRI 
    VKPNNNNMPS SDDGLEHNKI QNGKAPRDPV TENCVQGEEK ESSNDSTSVS AVASNMRDDE 
    ITQDENTVST SLGHSKDENS KQTCIRIGTK TPKSDSCTPT NTTVEVVGSS GQNGDEKQNI 
    VARKIVKMTK QPAKKKPPPS REKKVTRTIL AILLAFIITW APYNVMVLIN TFCAPCIPNT 
    VWTIGYWLCY INSTINPACY ALCNATFKKT FKHLLMCHYK NIGATR

Genular Protein ID: 3740387020

Symbol: Q6SL59_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15379890

Title: Multiple promoters drive tissue-specific expression of the human M muscarinic acetylcholine receptor gene.

PubMed ID: 15379890

DOI: 10.1111/j.1471-4159.2004.02694.x

Sequence Information:

  • Length: 13
  • Mass: 1353
  • Checksum: 1B95B61EED6CA5B4
  • Sequence:
  • MNNSTNSSNN SLA

Genular Protein ID: 2831036633

Symbol: Q86SJ1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14512373

Title: Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle.

PubMed ID: 14512373

DOI: 10.1165/rcmb.2003-0011OC

Sequence Information:

  • Length: 30
  • Mass: 3262
  • Checksum: 238EDC76DE52EB1F
  • Sequence:
  • MNNSTNSSNN SLALTSPYKT FEVVFIVLVA

Genular Protein ID: 3569902233

Symbol: Q6SL56_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15379890

Title: Multiple promoters drive tissue-specific expression of the human M muscarinic acetylcholine receptor gene.

PubMed ID: 15379890

DOI: 10.1111/j.1471-4159.2004.02694.x

Sequence Information:

  • Length: 72
  • Mass: 8269
  • Checksum: 8A833B2696817373
  • Sequence:
  • AFIITWAPYN VMVLINTFCA PCIPNTVWTI GYWLCYINST INPACYALCN ATFKKTFKHL 
    LMCHYKNIGA TR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.