Details for: ADCY7

Gene ID: 113

Symbol: ADCY7

Ensembl ID: ENSG00000121281

Description: adenylate cyclase 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 66.9902
    Cell Significance Index: -10.4200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 40.9630
    Cell Significance Index: -10.3900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 28.6026
    Cell Significance Index: -11.6200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 25.3312
    Cell Significance Index: -13.0300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 12.3908
    Cell Significance Index: -11.8300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.1325
    Cell Significance Index: -11.2600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.0652
    Cell Significance Index: -10.8900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.5342
    Cell Significance Index: -7.7400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.1093
    Cell Significance Index: -9.5500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1789
    Cell Significance Index: 224.3500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.9179
    Cell Significance Index: 24.6000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8215
    Cell Significance Index: 81.2600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5862
    Cell Significance Index: 12.4900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4125
    Cell Significance Index: 8.0500
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.4088
    Cell Significance Index: 1.1000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4051
    Cell Significance Index: 65.8800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3963
    Cell Significance Index: 43.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3592
    Cell Significance Index: 71.2800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2830
    Cell Significance Index: 8.3100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2787
    Cell Significance Index: 16.7300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2618
    Cell Significance Index: 16.8900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2572
    Cell Significance Index: 6.8800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2233
    Cell Significance Index: 6.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1951
    Cell Significance Index: 13.4900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1600
    Cell Significance Index: 3.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1541
    Cell Significance Index: 7.7900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.1401
    Cell Significance Index: 2.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1187
    Cell Significance Index: 3.1700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1171
    Cell Significance Index: 80.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1156
    Cell Significance Index: 23.1900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1114
    Cell Significance Index: 39.9800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0953
    Cell Significance Index: 13.0900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0896
    Cell Significance Index: 1.3500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0742
    Cell Significance Index: 8.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0590
    Cell Significance Index: 3.3100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0320
    Cell Significance Index: 3.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0208
    Cell Significance Index: 0.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0198
    Cell Significance Index: 0.4300
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.0122
    Cell Significance Index: 0.1300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0066
    Cell Significance Index: 0.1900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0032
    Cell Significance Index: 1.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0007
    Cell Significance Index: 1.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0030
    Cell Significance Index: -5.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0055
    Cell Significance Index: -4.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0056
    Cell Significance Index: -10.3900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0065
    Cell Significance Index: -0.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0087
    Cell Significance Index: -11.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0130
    Cell Significance Index: -5.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0135
    Cell Significance Index: -2.4300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0154
    Cell Significance Index: -9.8100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0171
    Cell Significance Index: -12.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0183
    Cell Significance Index: -0.8300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0214
    Cell Significance Index: -13.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0237
    Cell Significance Index: -13.3500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0252
    Cell Significance Index: -7.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0262
    Cell Significance Index: -11.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0404
    Cell Significance Index: -5.8700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0495
    Cell Significance Index: -5.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0498
    Cell Significance Index: -6.1200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0654
    Cell Significance Index: -13.7700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0743
    Cell Significance Index: -12.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0774
    Cell Significance Index: -2.4800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0782
    Cell Significance Index: -1.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0800
    Cell Significance Index: -10.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0868
    Cell Significance Index: -4.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0960
    Cell Significance Index: -11.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0962
    Cell Significance Index: -12.3300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1036
    Cell Significance Index: -2.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1045
    Cell Significance Index: -10.8800
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.1111
    Cell Significance Index: -0.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1135
    Cell Significance Index: -8.7100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1358
    Cell Significance Index: -3.4700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1465
    Cell Significance Index: -8.9800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1496
    Cell Significance Index: -7.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1633
    Cell Significance Index: -12.1700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1691
    Cell Significance Index: -10.4000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1733
    Cell Significance Index: -12.2600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1736
    Cell Significance Index: -11.6800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1790
    Cell Significance Index: -2.5700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1829
    Cell Significance Index: -9.5000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1906
    Cell Significance Index: -6.2400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1920
    Cell Significance Index: -2.7500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1948
    Cell Significance Index: -12.2800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2184
    Cell Significance Index: -2.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2226
    Cell Significance Index: -7.0900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.2245
    Cell Significance Index: -1.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2287
    Cell Significance Index: -12.0100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2433
    Cell Significance Index: -10.7600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2458
    Cell Significance Index: -11.4600
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.2667
    Cell Significance Index: -3.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2670
    Cell Significance Index: -9.3600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2705
    Cell Significance Index: -11.7600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2857
    Cell Significance Index: -10.8200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2858
    Cell Significance Index: -10.4900
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.2864
    Cell Significance Index: -1.9000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2929
    Cell Significance Index: -5.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3084
    Cell Significance Index: -8.8000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3098
    Cell Significance Index: -5.3400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3101
    Cell Significance Index: -6.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ADCY7 is a member of the adenylate cyclase family, which is involved in the regulation of cAMP levels in response to various ligands. The enzyme is highly expressed in cells of the central nervous system (CNS), including macrophages, neurons, and glial cells. ADCY7 is also found in immune cells, such as monocytes and lymphoid lineage-restricted progenitor cells, suggesting its role in immune regulation. The protein is characterized by its ability to activate adenylate cyclase, leading to the production of cAMP, which in turn modulates various cellular processes, including gene expression, cell proliferation, and differentiation. **Pathways and Functions:** ADCY7 is involved in several signaling pathways, including: 1. **GABA receptor activation**: ADCY7 modulates the activity of GABA receptors, which are involved in neurotransmission and synaptic plasticity. 2. **Adenylate cyclase-activating GPCR signaling pathway**: ADCY7 activates adenylate cyclase in response to various ligands, leading to the production of cAMP. 3. **Adenylate cyclase-inhibiting GPCR signaling pathway**: ADCY7 also inhibits adenylate cyclase, leading to the suppression of cAMP production. 4. **Anti-inflammatory response**: ADCY7 modulates the production of anti-inflammatory cytokines, such as IL-10, which is involved in the regulation of immune responses. 5. **Leishmania parasite infection**: ADCY7 is involved in the regulation of Leishmania parasite growth and survival, highlighting its role in parasitic infections. **Clinical Significance:** ADCY7 has been implicated in various immune-related diseases, including: 1. **Autoimmune diseases**: ADCY7 has been linked to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, where it modulates the production of inflammatory cytokines. 2. **Infectious diseases**: ADCY7 is involved in the regulation of Leishmania parasite growth and survival, which has implications for the treatment of leishmaniasis. 3. **Neurological disorders**: ADCY7 has been implicated in neurological disorders, such as schizophrenia and bipolar disorder, where it modulates neurotransmission and synaptic plasticity. 4. **Metabolic disorders**: ADCY7 is involved in the regulation of glucose and lipid metabolism, which has implications for the treatment of metabolic disorders, such as type 2 diabetes. In conclusion, ADCY7 is a complex enzyme involved in various cellular signaling pathways, including those related to immune regulation, neurotransmission, and metabolism. Its dysregulation has been implicated in various immune-related diseases, highlighting the need for further research into the mechanisms of ADCY7 and its potential therapeutic applications.

Genular Protein ID: 2012471018

Symbol: ADCY7_HUMAN

Name: ATP pyrophosphate-lyase 7

UniProtKB Accession Codes:

P51828 A0AVA6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 17 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 EMBL 3 Ensembl 3 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 13 RefSeq 2 Rhea 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12454008

Title: Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C delta.

PubMed ID: 12454008

DOI: 10.1074/jbc.m210386200

PubMed ID: 15581358

Title: A soluble C1b protein and its regulation of soluble type 7 adenylyl cyclase.

PubMed ID: 15581358

DOI: 10.1021/bi049088+

PubMed ID: 18541530

Title: Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII.

PubMed ID: 18541530

DOI: 10.1074/jbc.m803281200

PubMed ID: 23229509

Title: Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway.

PubMed ID: 23229509

DOI: 10.1124/mol.112.082446

PubMed ID: 23842570

Title: Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(betagamma) subunits in human embryonic kidney 293T cells.

PubMed ID: 23842570

DOI: 10.1124/mol.113.087288

Sequence Information:

  • Length: 1080
  • Mass: 120308
  • Checksum: E33951621E281242
  • Sequence:
    • MPAKGRYFLN EGEEGPDQDA LYEKYQLTSQ HGPLLLTLLL VAATACVALI IIAFSQGDPS 
RHQAILGMAF LVLAVFAALS VLMYVECLLR RWLRALALLT WACLVALGYV LVFDAWTKAA 
CAWEQVPFFL FIVFVVYTLL PFSMRGAVAV GAVSTASHLL VLGSLMGGFT TPSVRVGLQL 
LANAVIFLCG NLTGAFHKHQ MQDASRDLFT YTVKCIQIRR KLRIEKRQQE NLLLSVLPAH 
ISMGMKLAII ERLKEHGDRR CMPDNNFHSL YVKRHQNVSI LYADIVGFTQ LASDCSPKEL 
VVVLNELFGK FDQIAKANEC MRIKILGDCY YCVSGLPVSL PTHARNCVKM GLDMCQAIKQ 
VREATGVDIN MRVGIHSGNV LCGVIGLRKW QYDVWSHDVS LANRMEAAGV PGRVHITEAT 
LKHLDKAYEV EDGHGQQRDP YLKEMNIRTY LVIDPRSQQP PPPSQHLPRP KGDAALKMRA 
SVRMTRYLES WGAARPFAHL NHRESVSSGE THVPNGRRPK SVPQRHRRTP DRSMSPKGRS 
EDDSYDDEML SAIEGLSSTR PCCSKSDDFY TFGSIFLEKG FEREYRLAPI PRARHDFACA 
SLIFVCILLV HVLLMPRTAA LGVSFGLVAC VLGLVLGLCF ATKFSRCCPA RGTLCTISER 
VETQPLLRLT LAVLTIGSLL TVAIINLPLM PFQVPELPVG NETGLLAASS KTRALCEPLP 
YYTCSCVLGF IACSVFLRMS LEPKVVLLTV ALVAYLVLFN LSPCWQWDCC GQGLGNLTKP 
NGTTSGTPSC SWKDLKTMTN FYLVLFYITL LTLSRQIDYY CRLDCLWKKK FKKEHEEFET 
MENVNRLLLE NVLPAHVAAH FIGDKLNEDW YHQSYDCVCV MFASVPDFKV FYTECDVNKE 
GLECLRLLNE IIADFDELLL KPKFSGVEKI KTIGSTYMAA AGLSVASGHE NQELERQHAH 
IGVMVEFSIA LMSKLDGINR HSFNSFRLRV GINHGPVIAG VIGARKPQYD IWGNTVNVAS 
RMESTGELGK IQVTEETCTI LQGLGYSCEC RGLINVKGKG ELRTYFVCTD TAKFQGLGLN

Genular Protein ID: 175877627

Symbol: B3KSJ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KSJ0

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 6 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 Rhea 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 734
  • Mass: 81497
  • Checksum: ECD6B385B8D416CC
  • Sequence:
    • MPAKGRYFLN EGEEGPDQDA LYEKYQLTSQ HGPLLLTLLL VAATACVALI IIAFSQGDPS 
RHQAILGMAF LVLAVFAALS VLMYVECLLR RWLRALALLT WACLVALGYV LVFDAWTKAA 
CAWEQVPFFL FIVFVVYTLL PFSMRGAVAV GAVSTASHLL VLGSLMGGFT TPSVRVGLQL 
LANAVIFLCG NLTGAFHKHQ MQDASRDLFT YTVKCIQIRR KLRIEKRQQE NLLLSVLPAH 
ISMGMKLAII ERLKEHGDRR CMPDNNFHSL YVKRHQNVSI LYADIVGFTQ LASDCSPKEL 
VVVLNELFGK FDQIAKANEC MRIKILGDCY YCVSGLPVSL PTHARNCVKM GLDMCQAIKQ 
VREATGVDIN MRVGIHSGNV LCGVIGLRKW QYDVWSHDVS LANRMEAAGV PGRVHITEAT 
LKHLDKAYEV EDGRGQQRDP YLKEMNIRTY LVIDPRSQQP PPPSQHLPRP KGDAALKMRA 
SVRMTRYLES WGAARPFAHL NHRESVSSGE THVPNGRRPK SVPQRHRRTP DRSMSPKGRS 
EDDSYDDEML SAIEGLSSTR PCCSKSDDFY TFGSIFLEKG FEREYRLAPI PRARHDFACA 
SLIFVCILLV HVLLMPRTAA LGVSFGLVAC VLGLVLGLCF ATKFSRCCPA RGTLCTISER 
VETQPLLRLT LAVLTIGSLL TVAIINLPLM PFQVPELPVG NETGLLAASS KTRALCEPLP 
HLHTVFSRLN ELTS

Genular Protein ID: 1310842098

Symbol: Q86YI0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86YI0

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 6 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 Rhea 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 433
  • Mass: 48088
  • Checksum: 575A9150E376F013
  • Sequence:
    • MPAKGRYFLN EGEEGPDQDA LYEKYQLTSQ HGPLLLTLLL VAATACVALI IIAFSQGDPS 
RHQAILGMAF LVLAVFAALS VLMYVECLLR RWLRALALLT WACLVALGYV LVFDAWTKAA 
CAWEQVPFFL FIVFVVYTLL PFSMRGAVAV GAVSTASHLL VLGSLMGGFT TPSVRVGLQL 
LANAVIFLCG NLTGAFHKHQ MQDASRDLFT YTVKCIQIRR KLRIEKRQQE NLLLSVLPAH 
ISMGMKLAII ERLKEHGDRR CMPDNNFHSL YVKRHQNVSI LYADIVGFTQ LASDCSPKEL 
VVVLNELFGK FDQIAKANEC MRIKILGDCY YCVSGLPVSL PTHARNCVKM GLDMCQAIKQ 
VREATGVDIN MRVGIHSGNV LCGVIGLRKW QYDVWSHDVS LANRMEAAGV PGRVHITEAT 
LKHLDEALLL QVR

Genular Protein ID: 389711575

Symbol: F5H4D1_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5H4D1

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 2 Rhea 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 734
  • Mass: 81478
  • Checksum: F2FA68E3C5F2E504
  • Sequence:
    • MPAKGRYFLN EGEEGPDQDA LYEKYQLTSQ HGPLLLTLLL VAATACVALI IIAFSQGDPS 
RHQAILGMAF LVLAVFAALS VLMYVECLLR RWLRALALLT WACLVALGYV LVFDAWTKAA 
CAWEQVPFFL FIVFVVYTLL PFSMRGAVAV GAVSTASHLL VLGSLMGGFT TPSVRVGLQL 
LANAVIFLCG NLTGAFHKHQ MQDASRDLFT YTVKCIQIRR KLRIEKRQQE NLLLSVLPAH 
ISMGMKLAII ERLKEHGDRR CMPDNNFHSL YVKRHQNVSI LYADIVGFTQ LASDCSPKEL 
VVVLNELFGK FDQIAKANEC MRIKILGDCY YCVSGLPVSL PTHARNCVKM GLDMCQAIKQ 
VREATGVDIN MRVGIHSGNV LCGVIGLRKW QYDVWSHDVS LANRMEAAGV PGRVHITEAT 
LKHLDKAYEV EDGHGQQRDP YLKEMNIRTY LVIDPRSQQP PPPSQHLPRP KGDAALKMRA 
SVRMTRYLES WGAARPFAHL NHRESVSSGE THVPNGRRPK SVPQRHRRTP DRSMSPKGRS 
EDDSYDDEML SAIEGLSSTR PCCSKSDDFY TFGSIFLEKG FEREYRLAPI PRARHDFACA 
SLIFVCILLV HVLLMPRTAA LGVSFGLVAC VLGLVLGLCF ATKFSRCCPA RGTLCTISER 
VETQPLLRLT LAVLTIGSLL TVAIINLPLM PFQVPELPVG NETGLLAASS KTRALCEPLP 
HLHTVFSRLN ELTS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.