Details for: LYST

Gene ID: 1130

Symbol: LYST

Ensembl ID: ENSG00000143669

Description: lysosomal trafficking regulator

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.99
    Marker Score: 3619
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.66
    Marker Score: 3580
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.6
    Marker Score: 145343
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.59
    Marker Score: 1289
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.51
    Marker Score: 84840
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 2.45
    Marker Score: 5913
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.45
    Marker Score: 777
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.37
    Marker Score: 9907
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.32
    Marker Score: 46099
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2.25
    Marker Score: 5596
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.23
    Marker Score: 17096
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 2.2
    Marker Score: 4284
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.19
    Marker Score: 82995
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.18
    Marker Score: 80465.5
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.16
    Marker Score: 632
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.13
    Marker Score: 2649
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.11
    Marker Score: 882
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.07
    Marker Score: 11112.5
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.06
    Marker Score: 44015
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.06
    Marker Score: 743
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.05
    Marker Score: 30625
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.02
    Marker Score: 1208
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2
    Marker Score: 5601
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.99
    Marker Score: 8263
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 1.98
    Marker Score: 1583
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.97
    Marker Score: 121090
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.96
    Marker Score: 9055.5
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.96
    Marker Score: 2252
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.94
    Marker Score: 7893.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.93
    Marker Score: 3718.5
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.91
    Marker Score: 650
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.89
    Marker Score: 1100.5
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.89
    Marker Score: 7294.5
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.87
    Marker Score: 1094
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.85
    Marker Score: 1823
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.82
    Marker Score: 17257
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.8
    Marker Score: 18608
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.79
    Marker Score: 1029
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.78
    Marker Score: 1961.5
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.76
    Marker Score: 16524
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.73
    Marker Score: 14845.5
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.73
    Marker Score: 4930
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.72
    Marker Score: 514
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.71
    Marker Score: 737
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.68
    Marker Score: 421
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.6
    Marker Score: 690
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.6
    Marker Score: 18592
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.59
    Marker Score: 434
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.55
    Marker Score: 2257
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.55
    Marker Score: 2704
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 1.55
    Marker Score: 509
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.54
    Marker Score: 2370
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.5
    Marker Score: 3291
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.49
    Marker Score: 786
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.47
    Marker Score: 724
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.46
    Marker Score: 2062
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.42
    Marker Score: 2986
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.42
    Marker Score: 7456
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.41
    Marker Score: 1111
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.41
    Marker Score: 712
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.41
    Marker Score: 615
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.41
    Marker Score: 6903.5
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.4
    Marker Score: 298
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.39
    Marker Score: 564
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.38
    Marker Score: 510
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 1.37
    Marker Score: 1149
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.36
    Marker Score: 1228
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.35
    Marker Score: 520
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.35
    Marker Score: 325
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.33
    Marker Score: 1182
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.33
    Marker Score: 21377
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.33
    Marker Score: 420
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.33
    Marker Score: 45113
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.32
    Marker Score: 13038
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.3
    Marker Score: 491
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.3
    Marker Score: 1128
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 1.3
    Marker Score: 1358
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 1.28
    Marker Score: 416
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 1.26
    Marker Score: 1860
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.26
    Marker Score: 398
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.26
    Marker Score: 32215.5
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 1.25
    Marker Score: 271.5
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.24
    Marker Score: 1142.5
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.24
    Marker Score: 243
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.24
    Marker Score: 786
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.24
    Marker Score: 689
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.23
    Marker Score: 3005.5
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.23
    Marker Score: 1519
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.23
    Marker Score: 1694
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.22
    Marker Score: 394
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 1.22
    Marker Score: 630
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 1.22
    Marker Score: 271.5
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.2
    Marker Score: 417
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.2
    Marker Score: 449
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 1.19
    Marker Score: 262.5
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.19
    Marker Score: 1259
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.19
    Marker Score: 1433
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 1.19
    Marker Score: 532
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.19
    Marker Score: 914
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.17
    Marker Score: 1657

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Other Information

**Key characteristics:** - LYST is a transmembrane protein with a molecular weight of approximately 130 kDa. - It is expressed in a variety of cell types, including lens epithelial cells, monocytes, and macrophages. - LYST is a key regulator of lysosomal trafficking, and mutations in the gene can lead to lysosomal disorders. **Pathways and functions:** - LYST is involved in the regulation of lysosomal trafficking from the endoplasmic reticulum (ER) to the lysosome. - It does this by interacting with the E1-E3 ubiquitin-proteasome pathway, which is responsible for targeting proteins for degradation. - LYST also regulates the sorting of lysosomes to different cellular compartments, including the lysosome, endosomes, and the plasma membrane. - By controlling the trafficking of lysosomes, LYST plays a role in a variety of cellular processes, including cell migration, differentiation, and apoptosis. **Clinical significance:** - Mutations in the LYST gene can lead to lysosomal disorders, which are characterized by a variety of clinical symptoms, including progressive blindness, hearing loss, and intellectual disability. - These disorders can be caused by mutations in either the LYST gene or by mutations in genes that are involved in the regulation of lysosomal trafficking. - LYST is a potential therapeutic target for lysosomal disorders, and the development of drugs that target the LYST gene is an area of active research.

Genular Protein ID: 2059824034

Symbol: LYST_HUMAN

Name: Lysosomal-trafficking regulator

UniProtKB Accession Codes:

Q99698 O43274 Q5T2U9 Q96TD7 Q96TD8 Q99709 Q9H133

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 16 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 5 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8896560

Title: Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome.

PubMed ID: 8896560

DOI: 10.1038/ng1196-307

PubMed ID: 8717042

Title: Identification of the homologous beige and Chediak-Higashi syndrome genes.

PubMed ID: 8717042

DOI: 10.1038/382262a0

PubMed ID: 9215680

Title: Identification of mutations in two major mRNA isoforms of the Chediak-Higashi syndrome gene in human and mouse.

PubMed ID: 9215680

DOI: 10.1093/hmg/6.7.1091

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 11984006

Title: The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

PubMed ID: 11984006

DOI: 10.1007/bf03402003

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 11857544

Title: Apparent genotype-phenotype correlation in childhood, adolescent, and adult Chediak-Higashi syndrome.

PubMed ID: 11857544

DOI: 10.1002/ajmg.10184.abs

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25216107

Title: LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis.

PubMed ID: 25216107

DOI: 10.1111/tra.12227

PubMed ID: 25425525

Title: LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function.

PubMed ID: 25425525

DOI: 10.1111/tra.12244

PubMed ID: 26478006

Title: Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells.

PubMed ID: 26478006

DOI: 10.1016/j.jaci.2015.08.039

PubMed ID: 27881733

Title: Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor-mediated inflammatory responses.

PubMed ID: 27881733

DOI: 10.1084/jem.20141461

PubMed ID: 20368792

Title: Two novel mutations identified in an african-american child with chediak-higashi syndrome.

PubMed ID: 20368792

DOI: 10.1155/2010/967535

PubMed ID: 24521565

Title: Autosomal-recessive complicated spastic paraplegia with a novel lysosomal trafficking regulator gene mutation.

PubMed ID: 24521565

DOI: 10.1136/jnnp-2013-306981

PubMed ID: 31906877

Title: Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome.

PubMed ID: 31906877

DOI: 10.1186/s12881-019-0922-8

Sequence Information:

  • Length: 3801
  • Mass: 429139
  • Checksum: E11BAB6357059D17
  • Sequence:
    • MSTDSNSLAR EFLTDVNRLC NAVVQRVEAR EEEEEETHMA TLGQYLVHGR GFLLLTKLNS 
IIDQALTCRE ELLTLLLSLL PLVWKIPVQE EKATDFNLPL SADIILTKEK NSSSQRSTQE 
KLHLEGSALS SQVSAKVNVF RKSRRQRKIT HRYSVRDARK TQLSTSDSEA NSDEKGIAMN 
KHRRPHLLHH FLTSFPKQDH PKAKLDRLAT KEQTPPDAMA LENSREIIPR QGSNTDILSE 
PAALSVISNM NNSPFDLCHV LLSLLEKVCK FDVTLNHNSP LAASVVPTLT EFLAGFGDCC 
SLSDNLESRV VSAGWTEEPV ALIQRMLFRT VLHLLSVDVS TAEMMPENLR KNLTELLRAA 
LKIRICLEKQ PDPFAPRQKK TLQEVQEDFV FSKYRHRALL LPELLEGVLQ ILICCLQSAA 
SNPFYFSQAM DLVQEFIQHH GFNLFETAVL QMEWLVLRDG VPPEASEHLK ALINSVMKIM 
STVKKVKSEQ LHHSMCTRKR HRRCEYSHFM HHHRDLSGLL VSAFKNQVSK NPFEETADGD 
VYYPERCCCI AVCAHQCLRL LQQASLSSTC VQILSGVHNI GICCCMDPKS VIIPLLHAFK 
LPALKNFQQH ILNILNKLIL DQLGGAEISP KIKKAACNIC TVDSDQLAQL EETLQGNLCD 
AELSSSLSSP SYRFQGILPS SGSEDLLWKW DALKAYQNFV FEEDRLHSIQ IANHICNLIQ 
KGNIVVQWKL YNYIFNPVLQ RGVELAHHCQ HLSVTSAQSH VCSHHNQCLP QDVLQIYVKT 
LPILLKSRVI RDLFLSCNGV SQIIELNCLN GIRSHSLKAF ETLIISLGEQ QKDASVPDID 
GIDIEQKELS SVHVGTSFHH QQAYSDSPQS LSKFYAGLKE AYPKRRKTVN QDVHINTINL 
FLCVAFLCVS KEAESDRESA NDSEDTSGYD STASEPLSHM LPCISLESLV LPSPEHMHQA 
ADIWSMCRWI YMLSSVFQKQ FYRLGGFRVC HKLIFMIIQK LFRSHKEEQG KKEGDTSVNE 
NQDLNRISQP KRTMKEDLLS LAIKSDPIPS ELGSLKKSAD SLGKLELQHI SSINVEEVSA 
TEAAPEEAKL FTSQESETSL QSIRLLEALL AICLHGARTS QQKMELELPN QNLSVESILF 
EMRDHLSQSK VIETQLAKPL FDALLRVALG NYSADFEHND AMTEKSHQSA EELSSQPGDF 
SEEAEDSQCC SFKLLVEEEG YEADSESNPE DGETQDDGVD LKSETEGFSA SSSPNDLLEN 
LTQGEIIYPE ICMLELNLLS ASKAKLDVLA HVFESFLKII RQKEKNVFLL MQQGTVKNLL 
GGFLSILTQD DSDFQACQRV LVDLLVSLMS SRTCSEELTL LLRIFLEKSP CTKILLLGIL 
KIIESDTTMS PSQYLTFPLL HAPNLSNGVS SQKYPGILNS KAMGLLRRAR VSRSKKEADR 
ESFPHRLLSS WHIAPVHLPL LGQNCWPHLS EGFSVSLWFN VECIHEAEST TEKGKKIKKR 
NKSLILPDSS FDGTESDRPE GAEYINPGER LIEEGCIHII SLGSKALMIQ VWADPHNATL 
IFRVCMDSND DMKAVLLAQV ESQENIFLPS KWQHLVLTYL QQPQGKRRIH GKISIWVSGQ 
RKPDVTLDFM LPRKTSLSSD SNKTFCMIGH CLSSQEEFLQ LAGKWDLGNL LLFNGAKVGS 
QEAFYLYACG PNHTSVMPCK YGKPVNDYSK YINKEILRCE QIRELFMTKK DVDIGLLIES 
LSVVYTTYCP AQYTIYEPVI RLKGQMKTQL SQRPFSSKEV QSILLEPHHL KNLQPTEYKT 
IQGILHEIGG TGIFVFLFAR VVELSSCEET QALALRVILS LIKYNQQRVH ELENCNGLSM 
IHQVLIKQKC IVGFYILKTL LEGCCGEDII YMNENGEFKL DVDSNAIIQD VKLLEELLLD 
WKIWSKAEQG VWETLLAALE VLIRADHHQQ MFNIKQLLKA QVVHHFLLTC QVLQEYKEGQ 
LTPMPREVCR SFVKIIAEVL GSPPDLELLT IIFNFLLAVH PPTNTYVCHN PTNFYFSLHI 
DGKIFQEKVR SIMYLRHSSS GGRSLMSPGF MVISPSGFTA SPYEGENSSN IIPQQMAAHM 
LRSRSLPAFP TSSLLTQSQK LTGSLGCSID RLQNIADTYV ATQSKKQNSL GSSDTLKKGK 
EDAFISSCES AKTVCEMEAV LSAQVSVSDV PKGVLGFPVV KADHKQLGAE PRSEDDSPGD 
ESCPRRPDYL KGLASFQRSH STIASLGLAF PSQNGSAAVG RWPSLVDRNT DDWENFAYSL 
GYEPNYNRTA SAHSVTEDCL VPICCGLYEL LSGVLLILPD VLLEDVMDKL IQADTLLVLV 
NHPSPAIQQG VIKLLDAYFA RASKEQKDKF LKNRGFSLLA NQLYLHRGTQ ELLECFIEMF 
FGRHIGLDEE FDLEDVRNMG LFQKWSVIPI LGLIETSLYD NILLHNALLL LLQILNSCSK 
VADMLLDNGL LYVLCNTVAA LNGLEKNIPM SEYKLLACDI QQLFIAVTIH ACSSSGSQYF 
RVIEDLIVML GYLQNSKNKR TQNMAVALQL RVLQAAMEFI RTTANHDSEN LTDSLQSPSA 
PHHAVVQKRK SIAGPRKFPL AQTESLLMKM RSVANDELHV MMQRRMSQEN PSQATETELA 
QRLQRLTVLA VNRIIYQEFN SDIIDILRTP ENVTQSKTSV FQTEISEENI HHEQSSVFNP 
FQKEIFTYLV EGFKVSIGSS KASGSKQQWT KILWSCKETF RMQLGRLLVH ILSPAHAAQE 
RKQIFEIVHE PNHQEILRDC LSPSLQHGAK LVLYLSELIH NHQGELTEEE LGTAELLMNA 
LKLCGHKCIP PSASTKADLI KMIKEEQKKY ETEEGVNKAA WQKTVNNNQQ SLFQRLDSKS 
KDISKIAADI TQAVSLSQGN ERKKVIQHIR GMYKVDLSAS RHWQELIQQL THDRAVWYDP 
IYYPTSWQLD PTEGPNRERR RLQRCYLTIP NKYLLRDRQK SEDVVKPPLS YLFEDKTHSS 
FSSTVKDKAA SESIRVNRRC ISVAPSRETA GELLLGKCGM YFVEDNASDT VESSSLQGEL 
EPASFSWTYE EIKEVHKRWW QLRDNAVEIF LTNGRTLLLA FDNTKVRDDV YHNILTNNLP 
NLLEYGNITA LTNLWYTGQI TNFEYLTHLN KHAGRSFNDL MQYPVFPFIL ADYVSETLDL 
NDLLIYRNLS KPIAVQYKEK EDRYVDTYKY LEEEYRKGAR EDDPMPPVQP YHYGSHYSNS 
GTVLHFLVRM PPFTKMFLAY QDQSFDIPDR TFHSTNTTWR LSSFESMTDV KELIPEFFYL 
PEFLVNREGF DFGVRQNGER VNHVNLPPWA RNDPRLFILI HRQALESDYV SQNICQWIDL 
VFGYKQKGKA SVQAINVFHP ATYFGMDVSA VEDPVQRRAL ETMIKTYGQT PRQLFHMAHV 
SRPGAKLNIE GELPAAVGLL VQFAFRETRE QVKEITYPSP LSWIKGLKWG EYVGSPSAPV 
PVVCFSQPHG ERFGSLQALP TRAICGLSRN FCLLMTYSKE QGVRSMNSTD IQWSAILSWG 
YADNILRLKS KQSEPPVNFI QSSQQYQVTS CAWVPDSCQL FTGSKCGVIT AYTNRFTSST 
PSEIEMETQI HLYGHTEEIT SLFVCKPYSI LISVSRDGTC IIWDLNRLCY VQSLAGHKSP 
VTAVSASETS GDIATVCDSA GGGSDLRLWT VNGDLVGHVH CREIICSVAF SNQPEGVSIN 
VIAGGLENGI VRLWSTWDLK PVREITFPKS NKPIISLTFS CDGHHLYTAN SDGTVIAWCR 
KDQQRLKQPM FYSFLSSYAA G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.