Genular: Defining Cellular Identity and Function

Details for: Abca2

Gene ID: 11305

Symbol: Abca2

Ensembl ID: ENSMUSG00000026944

Description: ATP-binding cassette, sub-family A member 2

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Abc transporters in lipid homeostasis
(R-MMU-1369062)
Transport of small molecules
(R-MMU-382551)
Abc-type transporter activity
(GO:0140359)
Atpase-coupled transmembrane transporter activity
(GO:0042626)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Central nervous system myelin formation
(GO:0032289)
Ceramide floppase activity
(GO:0099038)
Ceramide translocation
(GO:0099040)
Cholesterol metabolic process
(GO:0008203)
Cytoplasmic vesicle
(GO:0031410)
Endopeptidase regulator activity
(GO:0061135)
Endosome
(GO:0005768)
Endosome membrane
(GO:0010008)
Ganglioside metabolic process
(GO:0001573)
Glycosphingolipid metabolic process
(GO:0006687)
Intracellular membrane-bounded organelle
(GO:0043231)
Intracellular sphingolipid homeostasis
(GO:0090156)
Lipid transport
(GO:0006869)
Lipid transporter activity
(GO:0005319)
Locomotory behavior
(GO:0007626)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Microtubule organizing center
(GO:0005815)
Negative regulation of cholesterol efflux
(GO:0090370)
Negative regulation of intracellular cholesterol transport
(GO:0032384)
Negative regulation of low-density lipoprotein receptor activity
(GO:1905598)
Negative regulation of phospholipid biosynthetic process
(GO:0071072)
Negative regulation of receptor-mediated endocytosis involved in cholesterol transport
(GO:1905601)
Negative regulation of sphingolipid biosynthetic process
(GO:0090155)
Negative regulation of steroid metabolic process
(GO:0045939)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Positive regulation of amyloid-beta formation
(GO:1902004)
Positive regulation of amyloid precursor protein biosynthetic process
(GO:0042986)
Positive regulation of amyloid precursor protein catabolic process
(GO:1902993)
Positive regulation of low-density lipoprotein particle receptor catabolic process
(GO:0032805)
Regulation of intracellular cholesterol transport
(GO:0032383)
Regulation of post-translational protein modification
(GO:1901873)
Regulation of protein glycosylation
(GO:0060049)
Regulation of protein localization to cell periphery
(GO:1904375)
Regulation of protein localization to cell surface
(GO:2000008)
Regulation of steroid metabolic process
(GO:0019218)
Sphingomyelin metabolic process
(GO:0006684)
Sphingosine biosynthetic process
(GO:0046512)
Transmembrane transport
(GO:0055085)

Other Information

Proteins

A2AJ26_MOUSE

Genular Protein ID: 859656030

Symbol: A2AJ26_MOUSE

Name: N/A

UniProtKB Accession Codes:

A2AJ26

Database IDs:

Citations:

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 2433
Mass: 270525
Checksum: D5E92BDFA06C0AF6
Sequence:

MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP 
LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLH RVVEEGNLFD PVRPSLGSEL 
EALRQRLEAL SSGPGTWESH SARPAVSSFS LDSVARDQRE LWRFLMQNLS LPNSTAQALL 
AARVDPSEVY RLLFGPLPDL DGKLGFLRKQ EPWSRLGSNP LLQMEELLLA PALLEQLTCA 
PGSGELGRIL TMPEGHQVDL QGYRDAVCSG QATARAQRFS DLAAELRNQL DTAKIAQQLG 
FDVPNGSDPQ PQAPSPQSLP ALLGDLLDAQ KLLQDVDVLS ALALLLPQGA CAGQASAPQA 
SSLNGLANST GIGANSGSNT TVEEGTQSPV SPASPDTLQG QCSAFVQLWA GLQPILCGNN 
RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPVGSEADR VILKANETFA 
FVGNVTHYAQ VWLNISTEIR SFLEQGRLQQ HLQWLQQYVA DLQLHPEAMN LSLEELPPAL 
RQDFSLPNGT ALLQQLDTID NAACGWIQFM SKVSVDIFKG FPDEESIVNY TLNQAYQDNV 
TVFASVIFQT RKDGSLPPHV HYKIRQNSSF TEKTNEIRRA YWRPGPNTGG RFYFLYGFVW 
IQDMMERAII NTFVGHDVVE PGNYVQMFPY PCYTRDDFLF VIEHMMPLCM VISWVYSVAM 
TIQHIVAEKE HRLKEVMKTM GLNNAVHWVA WFITGFVQLS ISVTALTAIL KYGQVLMHSH 
VLIIWLFLAV YAVATIMFCF LVSVLYSKAK LASACGGIIY FLSYVPYMYV AIREEVAHDK 
ITAFEKCIAS LMSTTAFGLG SKYFALYEVA GVGIQWHTFS QSPVEGDDFN LLLAVTMLMV 
DTVVYGVLTW YIEAVHPGMY GLPRPWYFPL QKSYWLGSGR TEAWEWSWPW AHTPRLSVME 
EDQACAMESR HFEETRGMEE EPTHLPLVVC VDKLTKVYKN DKKMALNKLS LNLYENQVVS 
FLGHNGAGKT TTMSILTGLF PPTSGSATIY GHDIRTEMDE IRKNLGMCPQ HNVLFDRLTV 
EEHLWFYSRL KSMAQEEIRK ETDKMIEDLE LSNKRHSLVQ TLSGGMKRKL SVAIAFVGGS 
RAIILDEPTA GVDPYARRAI WDLILKYKPG RTILLSTHHM DEADLLGDRI AIISHGKLKC 
CGSPLFLKGA YGDGYRLTLV KQPAEPGTSQ EPGLASSPSG CPRLSSCSEP QVSQFIRKHV 
ASSLLVSDTS TELSYILPSE AVKKGAFERL FQQLEHSLDA LHLSSFGLMD TTLEEVFLKV 
SEEDQSLENS EADVKESRKD VLPGAEGLTA VGGQAGNLAR CSELAQSQAS LQSASSVGSA 
RGEEGTGYSD GYGDYRPLFD NLQDPDNVSL QEAEMEALAQ VGQGSRKLEG WWLKMRQFHG 
LLVKRFHCAR RNSKALCSQI LLPAFFVCVA MTVALSVPEI GDLPPLVLSP SQYHNYTQPR 
GNFIPYANEE RQEYRLRLSP DASPQQLVST FRLPSGVGAT CVLKSPANGS LGPMLNLSSG 
ESRLLAARFF DSMCLESFTQ GLPLSNFVPP PPSPAPSDSP VSPDEDSLQA WNMSLPPTAG 
PETWTSAPSL PRLVHEPVRC TCSAQGTGFS CPSSVGGHPP QMRVVTGDIL TDITGHNVSE 
YLLFTSDRFR LHRYGAITFG NVQKSIPASF GARVPPMVRK IAVRRVAQVL YNNKGYHSMP 
TYLNSLNNAI LRANLPKSKG NPAAYGITVT NHPMNKTSAS LSLDYLLQGT DVVIAIFIIV 
AMSFVPASFV VFLVAEKSTK AKHLQFVSGC NPVIYWLANY VWDMLNYLVP ATCCVIILFV 
FDLPAYTSPT NFPAVLSLFL LYGWSITPIM YPASFWFEVP SSAYVFLIVI NLFIGITATV 
ATFLLQLFEH DKDLKVVNSY LKSCFLIFPN YNLGHGLMEM AYNEYINEYY AKIGQFDKMK 
SPFEWDIVTR GLVAMTVEGF VGFFLTIMCQ YNFLRQPQRL PVSTKPVEDD VDVASERQRV 
LRGDADNDMV KIENLTKVYK SRKIGRILAV DRLCLGVRPG ECFGLLGVNG AGKTSTFKML 
TGDESTTGGE AFVNGHSVLK DLLQVQQSLG YCPQFDALFD ELTAREHLQL YTRLRGIPWK 
DEAQVVKWAL EKLELTKYAD KPAGTYSGGN KRKLSTAIAL IGYPAFIFLD EPTTGMDPKA 
RRFLWNLILD LIKTGRSVVL TSHSMEECEA LCTRLAIMVN GRLRCLGSIQ HLKNRFGDGY 
MITVRTKSSQ NVKDVVRFFN RNFPEAMLKE RHHTKVQYQL KSEHISLAQV FSKMEQVVGV 
LGIEDYSVSQ TTLDNVFVNF AKKQSDNVEQ QEAEPSSLPS PLGLLSLLRP RPAPTELRAL 
VADEPEDLDT EDEGLISFEE ERAQLSFNTD TLC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.