Details for: SLCO2B1

Gene ID: 11309

Symbol: SLCO2B1

Ensembl ID: ENSG00000137491

Description: solute carrier organic anion transporter family member 2B1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 3.69
    Marker Score: 3,542
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 3.59
    Marker Score: 1,296
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.09
    Marker Score: 1,535
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.63
    Marker Score: 1,572
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 2.39
    Marker Score: 6,866
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.29
    Marker Score: 2,622
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.12
    Marker Score: 3,863
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.99
    Marker Score: 51,003
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.98
    Marker Score: 1,976
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.9
    Marker Score: 6,218
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.82
    Marker Score: 1,005
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.79
    Marker Score: 3,647
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.51
    Marker Score: 9,710
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 1.49
    Marker Score: 607
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,634
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.46
    Marker Score: 1,000
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.46
    Marker Score: 6,314
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.43
    Marker Score: 459
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.42
    Marker Score: 7,635
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.4
    Marker Score: 8,511
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 861
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.31
    Marker Score: 3,094
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.26
    Marker Score: 567
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.26
    Marker Score: 3,257
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1.19
    Marker Score: 495
  • Cell Name: macrophage (CL0000235)
    Fold Change: 1.11
    Marker Score: 1,238
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.04
    Marker Score: 9,118
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,802
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,026
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1
    Marker Score: 15,594
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 503
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 456
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,411
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.94
    Marker Score: 1,529
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,734
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 322
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,065
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.81
    Marker Score: 323
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 602
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.77
    Marker Score: 4,614
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.77
    Marker Score: 478
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 391
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.75
    Marker Score: 1,196
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.74
    Marker Score: 3,117
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.72
    Marker Score: 659
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.7
    Marker Score: 849
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.64
    Marker Score: 312
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.64
    Marker Score: 201
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.64
    Marker Score: 450
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.62
    Marker Score: 373
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.62
    Marker Score: 233
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.6
    Marker Score: 505
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.59
    Marker Score: 637
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 0.59
    Marker Score: 1,510
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.58
    Marker Score: 140
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.56
    Marker Score: 2,679
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 443
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.52
    Marker Score: 196
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.52
    Marker Score: 134
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.51
    Marker Score: 251
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.51
    Marker Score: 1,591
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.5
    Marker Score: 187
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.5
    Marker Score: 571
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.49
    Marker Score: 205
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.48
    Marker Score: 247
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.46
    Marker Score: 710
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.44
    Marker Score: 634
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.43
    Marker Score: 277
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.43
    Marker Score: 386
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.43
    Marker Score: 96
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.43
    Marker Score: 249
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.43
    Marker Score: 106
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.43
    Marker Score: 724
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.43
    Marker Score: 283
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.42
    Marker Score: 202
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.42
    Marker Score: 181
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.41
    Marker Score: 395
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4
    Marker Score: 765
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.4
    Marker Score: 182
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.4
    Marker Score: 227
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.39
    Marker Score: 1,393
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 0.39
    Marker Score: 563
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.38
    Marker Score: 378
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.36
    Marker Score: 367
  • Cell Name: colon macrophage (CL0009038)
    Fold Change: 0.36
    Marker Score: 100
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 0.36
    Marker Score: 111
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.35
    Marker Score: 234
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.35
    Marker Score: 178
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.35
    Marker Score: 675
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.34
    Marker Score: 340
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.34
    Marker Score: 555
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.33
    Marker Score: 286
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.32
    Marker Score: 3,327
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.32
    Marker Score: 497
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.32
    Marker Score: 101
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.32
    Marker Score: 217

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SLCO2B1 is a member of the solute carrier organic anion transporter family, which is involved in the transport of organic anions across cell membranes. This transporter exhibits sodium-independent organic anion transport activity, allowing it to facilitate the movement of a wide range of compounds, including drugs, xenobiotics, and endogenous molecules. SLCO2B1 is primarily localized to the apical plasma membrane of epithelial cells, where it plays a crucial role in the disposition of organic anions. **Pathways and Functions:** SLCO2B1 is involved in various transport pathways, including: 1. **Apical plasma membrane**: SLCO2B1 is primarily localized to the apical plasma membrane of epithelial cells, where it facilitates the transport of organic anions across the apical membrane. 2. **Basal plasma membrane**: SLCO2B1 is also expressed in the basal plasma membrane of epithelial cells, where it may participate in the transport of organic anions back to the apical membrane. 3. **Bile acid and bile salt transport**: SLCO2B1 has been shown to transport bile acids and bile salts, which are essential for the digestion and absorption of fat-soluble vitamins. 4. **Drug adme**: SLCO2B1 plays a critical role in the disposition of various drugs, including atorvastatin and aspirin, by facilitating their transport across cell membranes. 5. **Heme catabolic process**: SLCO2B1 is involved in the transport of heme, a critical component of hemoglobin, across cell membranes. **Clinical Significance:** SLCO2B1 has significant clinical implications, particularly in the context of drug disposition and metabolism. Variants in the SLC02B1 gene have been associated with altered pharmacokinetics and pharmacodynamics of various drugs, including: 1. **Atorvastatin**: SLCO2B1 variants have been linked to reduced atorvastatin plasma concentrations, which may increase the risk of cardiovascular events. 2. **Aspirin**: SLCO2B1 variants have been associated with altered aspirin plasma concentrations, which may impact the efficacy of antiplatelet therapy. 3. **Bile acid and lipid disorders**: SLCO2B1 variants may contribute to the development of bile acid and lipid disorders, such as cholestasis and hypercholesterolemia. In conclusion, SLCO2B1 is a critical organic anion transporter that plays a vital role in the disposition and metabolism of various compounds. Its clinical significance cannot be overstated, particularly in the context of drug therapy and the development of bile acid and lipid disorders. Further research is needed to fully elucidate the role of SLCO2B1 in human health and disease.

Genular Protein ID: 1659690833

Symbol: SO2B1_HUMAN

Name: Solute carrier organic anion transporter family member 2B1

UniProtKB Accession Codes:

O94956 A0A024R5I4 A8K2G9 B4DGA9 B4DTB0 E7ERN5 E9PPU8 Q9H2Z0 Q9UFU1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 76 DrugCentral 1 EMBL 12 Ensembl 2 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 4 RefSeq 3 Rhea 10 SAM 1 SMR 1 STRING 1 SUPFAM 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10873595

Title: Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

PubMed ID: 10873595

DOI: 10.1006/bbrc.2000.2922

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11159893

Title: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.

PubMed ID: 11159893

DOI: 10.1053/gast.2001.21176

PubMed ID: 11932330

Title: Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta.

PubMed ID: 11932330

DOI: 10.1210/jcem.87.4.8431

PubMed ID: 12409283

Title: Characterization and identification of steroid sulfate transporters of human placenta.

PubMed ID: 12409283

DOI: 10.1152/ajpendo.00257.2002

PubMed ID: 12724351

Title: Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

PubMed ID: 12724351

DOI: 10.1124/jpet.103.051300

PubMed ID: 14610227

Title: Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.

PubMed ID: 14610227

DOI: 10.1124/jpet.103.060194

PubMed ID: 16908597

Title: Modification of OATP2B1-mediated transport by steroid hormones.

PubMed ID: 16908597

DOI: 10.1124/mol.106.026450

PubMed ID: 16754786

Title: Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1.

PubMed ID: 16754786

DOI: 10.1124/mol.105.019547

PubMed ID: 18501590

Title: Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta.

PubMed ID: 18501590

DOI: 10.1016/j.jsbmb.2008.04.001

PubMed ID: 19129463

Title: Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

PubMed ID: 19129463

DOI: 10.1152/ajpcell.00436.2008

PubMed ID: 20507927

Title: pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions.

PubMed ID: 20507927

DOI: 10.1124/jpet.110.166314

PubMed ID: 22201122

Title: Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites.

PubMed ID: 22201122

DOI: 10.2133/dmpk.dmpk-11-sh-080

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23531488

Title: Transport function and transcriptional regulation of a liver-enriched human organic anion transporting polypeptide 2B1 transcriptional start site variant.

PubMed ID: 23531488

DOI: 10.1124/mol.112.083618

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26277985

Title: Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast.

PubMed ID: 26277985

DOI: 10.1113/jp270743

PubMed ID: 25132355

Title: Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS.

PubMed ID: 25132355

DOI: 10.1007/s00424-014-1596-x

Title: Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug-drug interaction.

DOI: 10.1039/C6MD00235H

PubMed ID: 27576593

Title: Tryptophan Residue Located at the Middle of Putative Transmembrane Domain 11 Is Critical for the Function of Organic Anion Transporting Polypeptide 2B1.

PubMed ID: 27576593

DOI: 10.1021/acs.molpharmaceut.6b00648

PubMed ID: 26383540

Title: Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.

PubMed ID: 26383540

DOI: 10.3109/00498254.2015.1085111

PubMed ID: 28408210

Title: The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.

PubMed ID: 28408210

DOI: 10.1016/j.xphs.2017.04.001

PubMed ID: 29871943

Title: Transmembrane Domain 1 of Human Organic Anion Transporting Polypeptide 2B1 Is Essential for Transporter Function and Stability.

PubMed ID: 29871943

DOI: 10.1124/mol.118.111914

PubMed ID: 34628357

Title: Differences in transport function of the human and rat orthologue of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1).

PubMed ID: 34628357

DOI: 10.1016/j.dmpk.2021.100418

PubMed ID: 35307651

Title: Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

PubMed ID: 35307651

DOI: 10.1124/dmd.121.000748

PubMed ID: 35714613

Title: Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability.

PubMed ID: 35714613

DOI: 10.1016/j.molcel.2022.05.024

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 709
  • Mass: 76699
  • Checksum: 61087C5E00F86D04
  • Sequence:
    • MGPRIGPAGE VPQVPDKETK ATMGTENTPG GKASPDPQDV RPSVFHNIKL FVLCHSLLQL 
AQLMISGYLK SSISTVEKRF GLSSQTSGLL ASFNEVGNTA LIVFVSYFGS RVHRPRMIGY 
GAILVALAGL LMTLPHFISE PYRYDNTSPE DMPQDFKASL CLPTTSAPAS APSNGNCSSY 
TETQHLSVVG IMFVAQTLLG VGGVPIQPFG ISYIDDFAHN SNSPLYLGIL FAVTMMGPGL 
AFGLGSLMLR LYVDINQMPE GGISLTIKDP RWVGAWWLGF LIAAGAVALA AIPYFFFPKE 
MPKEKRELQF RRKVLAVTDS PARKGKDSPS KQSPGESTKK QDGLVQIAPN LTVIQFIKVF 
PRVLLQTLRH PIFLLVVLSQ VCLSSMAAGM ATFLPKFLER QFSITASYAN LLIGCLSFPS 
VIVGIVVGGV LVKRLHLGPV GCGALCLLGM LLCLFFSLPL FFIGCSSHQI AGITHQTSAH 
PGLELSPSCM EACSCPLDGF NPVCDPSTRV EYITPCHAGC SSWVVQDALD NSQVFYTNCS 
CVVEGNPVLA GSCDSTCSHL VVPFLLLVSL GSALACLTHT PSFMLILRGV KKEDKTLAVG 
IQFMFLRILA WMPSPVIHGS AIDTTCVHWA LSCGRRAVCR YYNNDLLRNR FIGLQFFFKT 
GSVICFALVL AVLRQQDKEA RTKESRSSPA VEQQLLVSGP GKKPEDSRV

Genular Protein ID: 1696534060

Symbol: A0A0A0MTF1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MTF1

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 565
  • Mass: 61165
  • Checksum: ABDA6585DF53034F
  • Sequence:
    • MGPRIEDMPQ DFKASLCLPT TSAPASAPSN GNCSSYTETQ HLSVVGIMFV AQTLLGVGGV 
PIQPFGISYI DDFAHNSNSP LYLGILFAVT MMGPGLAFGL GSLMLRLYVD INQMPEGGIS 
LTIKDPRWVG AWWLGFLIAA GAVALAAIPY FFFPKEMPKE KRELQFRRKV LAVTDSPARK 
GKDSPSKQSP GESTKKQDGL VQIAPNLTVI QFIKVFPRVL LQTLRHPIFL LVVLSQVCLS 
SMAAGMATFL PKFLERQFSI TASYANLLIG CLSFPSVIVG IVVGGVLVKR LHLGPVGCGA 
LCLLGMLLCL FFSLPLFFIG CSSHQIAGIT HQTSAHPGLE LSPSCMEACS CPLDGFNPVC 
DPSTRVEYIT PCHAGCSSWV VQDALDNSQV FYTNCSCVVE GNPVLAGSCD STCSHLVVPF 
LLLVSLGSAL ACLTHTPSFM LILRGVKKED KTLAVGIQFM FLRILAWMPS PVIHGSAIDT 
TCVHWALSCG RRAVCRYYNN DLLRNRFIGL QFFFKTGSVI CFALVLAVLR QQDKEARTKE 
SRSSPAVEQQ LLVSGPGKKP EDSRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.