Details for: CHRM3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 4.73
Marker Score: 25,401 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 3.93
Marker Score: 20,603 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.81
Marker Score: 8,357 - Cell Name: macroglial cell (CL0000126)
Fold Change: 3.37
Marker Score: 7,739 - Cell Name: granule cell (CL0000120)
Fold Change: 3.26
Marker Score: 24,616 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 3.13
Marker Score: 1,122 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.89
Marker Score: 913 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.87
Marker Score: 57,078 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.8
Marker Score: 1,078 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.79
Marker Score: 21,404 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.73
Marker Score: 103,600 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.56
Marker Score: 4,298 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.5
Marker Score: 11,557 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.41
Marker Score: 36,041 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.33
Marker Score: 9,002 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.22
Marker Score: 1,289 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.06
Marker Score: 126,902 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.93
Marker Score: 18,309 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.87
Marker Score: 7,738 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.78
Marker Score: 4,062 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.73
Marker Score: 14,825 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.72
Marker Score: 7,166 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.72
Marker Score: 1,323 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.62
Marker Score: 2,499 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.61
Marker Score: 3,267 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.58
Marker Score: 495 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.48
Marker Score: 832 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,237 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.46
Marker Score: 3,441 - Cell Name: neuron (CL0000540)
Fold Change: 1.44
Marker Score: 5,879 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.44
Marker Score: 1,794 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.35
Marker Score: 565 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.34
Marker Score: 804 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.31
Marker Score: 48,259 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.18
Marker Score: 480 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.14
Marker Score: 1,308 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.12
Marker Score: 1,577 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.1
Marker Score: 370 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.1
Marker Score: 2,582 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.06
Marker Score: 749 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.05
Marker Score: 2,226 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.02
Marker Score: 488 - Cell Name: microglial cell (CL0000129)
Fold Change: 1.01
Marker Score: 1,835 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,793 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,018 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 504 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 458 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.97
Marker Score: 578 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.95
Marker Score: 20,328 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,411 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.95
Marker Score: 14,833 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,739 - Cell Name: germ cell (CL0000586)
Fold Change: 0.9
Marker Score: 1,578 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 323 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.9
Marker Score: 443 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.9
Marker Score: 5,110 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.88
Marker Score: 370 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.88
Marker Score: 1,431 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.87
Marker Score: 238 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,279 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.85
Marker Score: 8,816 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.85
Marker Score: 1,204 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.82
Marker Score: 630 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.82
Marker Score: 7,700 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.81
Marker Score: 387 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.81
Marker Score: 325 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.78
Marker Score: 731 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 0.76
Marker Score: 177 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.76
Marker Score: 2,160 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.75
Marker Score: 3,141 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.75
Marker Score: 2,510 - Cell Name: brush cell (CL0002204)
Fold Change: 0.72
Marker Score: 661 - Cell Name: monocyte (CL0000576)
Fold Change: 0.71
Marker Score: 929 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 0.71
Marker Score: 269 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.7
Marker Score: 341 - Cell Name: glomerular endothelial cell (CL0002188)
Fold Change: 0.7
Marker Score: 178 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.7
Marker Score: 574 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.69
Marker Score: 1,557 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.68
Marker Score: 838 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.68
Marker Score: 6,845 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.65
Marker Score: 169 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.64
Marker Score: 422 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.63
Marker Score: 556 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.62
Marker Score: 701 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.61
Marker Score: 196 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.61
Marker Score: 175 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.6
Marker Score: 352 - Cell Name: T cell (CL0000084)
Fold Change: 0.6
Marker Score: 1,027 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.6
Marker Score: 392 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.59
Marker Score: 205 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.59
Marker Score: 378 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 0.58
Marker Score: 418 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.58
Marker Score: 365 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.57
Marker Score: 689 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.57
Marker Score: 522 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.57
Marker Score: 5,687 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 226173587
Symbol: ACM3_HUMAN
Name: Muscarinic acetylcholine receptor M3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3443095
Title: Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.
PubMed ID: 3443095
PubMed ID: 3272174
Title: Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.
PubMed ID: 3272174
PubMed ID: 15014171
Title: Human-specific amino acid changes found in 103 protein-coding genes.
PubMed ID: 15014171
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11238933
Title: Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes.
PubMed ID: 11238933
PubMed ID: 7565628
Title: Mutation of carboxyl-terminal threonine residues in human M3 muscarinic acetylcholine receptor modulates the extent of sequestration and desensitization.
PubMed ID: 7565628
PubMed ID: 22077972
Title: Muscarinic acetylcholine receptor M3 mutation causes urinary bladder disease and a prune-belly-like syndrome.
PubMed ID: 22077972
PubMed ID: 21056967
Title: Regulation of M(3) muscarinic receptor expression and function by transmembrane protein 147.
PubMed ID: 21056967
PubMed ID: 23521066
Title: The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane.
PubMed ID: 23521066
DOI: 10.1042/bj20121902
PubMed ID: 15870063
Title: Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal.
PubMed ID: 15870063
Sequence Information:
- Length: 590
- Mass: 66128
- Checksum: 5CB473C57B9526E9
- Sequence:
MTLHNNSTTS PLFPNISSSW IHSPSDAGLP PGTVTHFGSY NVSRAAGNFS SPDGTTDDPL GGHTVWQVVF IAFLTGILAL VTIIGNILVI VSFKVNKQLK TVNNYFLLSL ACADLIIGVI SMNLFTTYII MNRWALGNLA CDLWLAIDYV ASNASVMNLL VISFDRYFSI TRPLTYRAKR TTKRAGVMIG LAWVISFVLW APAILFWQYF VGKRTVPPGE CFIQFLSEPT ITFGTAIAAF YMPVTIMTIL YWRIYKETEK RTKELAGLQA SGTEAETENF VHPTGSSRSC SSYELQQQSM KRSNRRKYGR CHFWFTTKSW KPSSEQMDQD HSSSDSWNNN DAAASLENSA SSDEEDIGSE TRAIYSIVLK LPGHSTILNS TKLPSSDNLQ VPEEELGMVD LERKADKLQA QKSVDDGGSF PKSFSKLPIQ LESAVDTAKT SDVNSSVGKS TATLPLSFKE ATLAKRFALK TRSQITKRKR MSLVKEKKAA QTLSAILLAF IITWTPYNIM VLVNTFCDSC IPKTFWNLGY WLCYINSTVN PVCYALCNKT FRTTFKMLLL CQCDKKKRRK QQYQQRQSVI FHKRAPEQAL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.