Details for: VPS45

Gene ID: 11311

Symbol: VPS45

Ensembl ID: ENSG00000136631

Description: vacuolar protein sorting 45 homolog

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 5.16
    Marker Score: 68,650
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 2.41
    Marker Score: 1,169
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.26
    Marker Score: 4,961
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.21
    Marker Score: 47,183
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.17
    Marker Score: 32,386
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.02
    Marker Score: 74,649
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.92
    Marker Score: 7,955
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.92
    Marker Score: 14,705
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.9
    Marker Score: 72,101
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.88
    Marker Score: 37,462
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.87
    Marker Score: 7,231
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.85
    Marker Score: 113,711
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.84
    Marker Score: 41,152
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.83
    Marker Score: 1,462
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.79
    Marker Score: 6,381
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.79
    Marker Score: 16,842
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.76
    Marker Score: 7,347
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.75
    Marker Score: 16,588
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.71
    Marker Score: 541
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.67
    Marker Score: 14,381
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.59
    Marker Score: 7,363
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.56
    Marker Score: 652
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.53
    Marker Score: 2,356
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.43
    Marker Score: 832
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.4
    Marker Score: 1,545
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.35
    Marker Score: 1,636
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.32
    Marker Score: 1,776
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.32
    Marker Score: 2,533
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.27
    Marker Score: 2,214
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.26
    Marker Score: 739
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.26
    Marker Score: 1,202
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.23
    Marker Score: 358
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.2
    Marker Score: 1,382
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.2
    Marker Score: 327
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.16
    Marker Score: 369
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.14
    Marker Score: 875
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.09
    Marker Score: 17,023
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.04
    Marker Score: 564
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.04
    Marker Score: 581
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.03
    Marker Score: 1,730
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.03
    Marker Score: 541
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.03
    Marker Score: 573
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.02
    Marker Score: 2,904
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.02
    Marker Score: 2,068
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.01
    Marker Score: 1,081
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,727
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,952
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.98
    Marker Score: 488
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,396
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.96
    Marker Score: 1,201
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.95
    Marker Score: 628
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 483
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.93
    Marker Score: 542
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.93
    Marker Score: 237
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 439
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.92
    Marker Score: 1,042
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.92
    Marker Score: 1,144
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,713
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.89
    Marker Score: 343
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.88
    Marker Score: 613
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.88
    Marker Score: 2,203
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4,910
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.86
    Marker Score: 924
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.85
    Marker Score: 471
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.84
    Marker Score: 857
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.84
    Marker Score: 501
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.84
    Marker Score: 309
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.81
    Marker Score: 214
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.81
    Marker Score: 1,316
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.8
    Marker Score: 5,174
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.8
    Marker Score: 289
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 0.8
    Marker Score: 2,136
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.77
    Marker Score: 310
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 0.77
    Marker Score: 403
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 0.76
    Marker Score: 463
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.75
    Marker Score: 3,258
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 575
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.75
    Marker Score: 663
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.75
    Marker Score: 215
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.74
    Marker Score: 272
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.74
    Marker Score: 233
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.73
    Marker Score: 272
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 376
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.72
    Marker Score: 640
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.71
    Marker Score: 243
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.71
    Marker Score: 999
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7
    Marker Score: 2,952
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 642
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.69
    Marker Score: 262
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.69
    Marker Score: 241
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.69
    Marker Score: 333
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.68
    Marker Score: 846
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.68
    Marker Score: 452
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.67
    Marker Score: 216
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.67
    Marker Score: 369
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.67
    Marker Score: 321

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** VPS45 is a member of the VPS family of proteins, which are involved in regulating the sorting and trafficking of proteins within the cell. Specifically, VPS45 is localized to the Golgi apparatus and is known to interact with various proteins, including those involved in protein binding, transport, and trafficking. Its expression is widespread, with significant levels detected in cardiac muscle cells, epicardial adipocytes, and various types of neurons. **Pathways and Functions** VPS45 plays a crucial role in several cellular pathways, including: 1. **Intra-Golgi and Retrograde Golgi-to-ER Traffic**: VPS45 is involved in regulating the transport of proteins from the Golgi apparatus to the endoplasmic reticulum (ER), which is essential for protein folding, modification, and secretion. 2. **Protein Binding and Trafficking**: VPS45 interacts with various proteins, including those involved in protein binding, transport, and trafficking, which is crucial for maintaining cellular homeostasis and responding to environmental stressors. 3. **Viral Infection Pathways**: VPS45 has been implicated in the regulation of viral infection pathways, including the modulation of autophagy and the interaction with SARS-CoV-2. **Clinical Significance** VPS45 has been associated with several diseases, including: 1. **Hemostasis Disorders**: VPS45 has been linked to hemostasis disorders, such as thrombocytopenia and platelet dysfunction, due to its role in regulating protein trafficking and binding. 2. **Infectious Diseases**: VPS45 has been implicated in the regulation of viral infection pathways, including SARS-CoV-2, and has been associated with severe COVID-19 outcomes. 3. **Neurological Disorders**: VPS45 has been linked to various neurological disorders, including epilepsy and autism spectrum disorder, due to its role in regulating protein trafficking and binding in neurons. In conclusion, VPS45 is a multifaceted gene that plays a critical role in regulating protein trafficking, binding, and trafficking, as well as immune response and disease pathogenesis. Further research is necessary to fully elucidate the mechanisms by which VPS45 contributes to disease outcomes and to explore its potential as a therapeutic target. **Recommendations for Future Research** 1. **Investigate VPS45's role in specific disease pathways**: Further research is necessary to elucidate VPS45's role in specific disease pathways, including hemostasis disorders, infectious diseases, and neurological disorders. 2. **Explore VPS45's interaction with other proteins**: The interaction between VPS45 and other proteins is crucial for understanding its role in protein trafficking and binding. Further research is necessary to identify and characterize these interactions. 3. **Develop therapeutic strategies targeting VPS45**: VPS45's involvement in disease pathogenesis makes it a potential therapeutic target. Further research is necessary to develop effective therapeutic strategies targeting VPS45. By continuing to explore the intricacies of VPS45's role in the immune system and disease pathogenesis, we can gain a deeper understanding of its clinical significance and develop effective therapeutic strategies to combat various diseases.

Genular Protein ID: 3923927044

Symbol: VPS45_HUMAN

Name: Vacuolar protein sorting-associated protein 45

UniProtKB Accession Codes:

Q9NRW7 D3DUZ9 F5H8K1 Q15715 Q53FR8 Q5T4P6 Q9Y4Z6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8996080

Title: Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking.

PubMed ID: 8996080

DOI: 10.1016/s0378-1119(96)00367-8

PubMed ID: 10404641

Title: Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (hlVps45).

PubMed ID: 10404641

DOI: 10.1016/s1357-2725(99)00017-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11062261

Title: Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain.

PubMed ID: 11062261

DOI: 10.1083/jcb.151.3.601

PubMed ID: 11788822

Title: Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.

PubMed ID: 11788822

DOI: 10.1038/ncb744

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23738510

Title: A congenital neutrophil defect syndrome associated with mutations in VPS45.

PubMed ID: 23738510

DOI: 10.1056/nejmoa1301296

Sequence Information:

  • Length: 570
  • Mass: 65077
  • Checksum: 5574F0BE3A7D4EB3
  • Sequence:
    • MNVVFAVKQY ISKMIEDSGP GMKVLLMDKE TTGIVSMVYT QSEILQKEVY LFERIDSQNR 
EIMKHLKAIC FLRPTKENVD YIIQELRRPK YTIYFIYFSN VISKSDVKSL AEADEQEVVA 
EVQEFYGDYI AVNPHLFSLN ILGCCQGRNW DPAQLSRTTQ GLTALLLSLK KCPMIRYQLS 
SEAAKRLAEC VKQVITKEYE LFEFRRTEVP PLLLILDRCD DAITPLLNQW TYQAMVHELL 
GINNNRIDLS RVPGISKDLR EVVLSAENDE FYANNMYLNF AEIGSNIKNL MEDFQKKKPK 
EQQKLESIAD MKAFVENYPQ FKKMSGTVSK HVTVVGELSR LVSERNLLEV SEVEQELACQ 
NDHSSALQNI KRLLQNPKVT EFDAARLVML YALHYERHSS NSLPGLMMDL RNKGVSEKYR 
KLVSAVVEYG GKRVRGSDLF SPKDAVAITK QFLKGLKGVE NVYTQHQPFL HETLDHLIKG 
RLKENLYPYL GPSTLRDRPQ DIIVFVIGGA TYEEALTVYN LNRTTPGVRI VLGGTTVHNT 
KSFLEEVLAS GLHSRSKESS QVTSRSASRR

Genular Protein ID: 2138615389

Symbol: B7Z360_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z360

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 3 GenomeRNAi 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SUPFAM 1

Sequence Information:

  • Length: 534
  • Mass: 61107
  • Checksum: 8FC6896E27D62D59
  • Sequence:
    • MVYTQSEILQ KEVYLFERID SQNREIMKHL KAICFLRPTK ENVDYIIQEL RRPKYTIYFI 
YFSNVISKSD VKSLAEADEQ EVVAEVQEFY GDYIAVNPHL FSLNILGCCQ GRNWDPAQLS 
RTTQGLTALL LSLKKCPMIR YQLSSEAAKR LAECVKQVIT KEYELFEFRR TEVPPLLLIL 
DRCDDAITPL LNQWTYQAMV HELLGINNNR IDLSRVPGIS KDLREVVLSA ENDEFYANNM 
YLNFAEIGSN IKNLMEDFQK KKPKEQQKLE SIADMKAFVE SYPQFKKMSG TVSKHVTVVG 
ELSRLVSERN LLEVSEVEQE LACQNDHSSA LQNIKRLLQN PKVTEFDAAR LVMLYALHYE 
RHSSNSLPGL MMDLRNKGVS EKYRKLVSAV VEYGGKRVRG SDLFSPKDAV AITKQFLKGL 
KGVENVYTQH QPFLHETLDH LIKGRLKENL YPYLGPSTLR DRPQDIIVFV IGGATYEEAL 
TVYNLNRTTP GVRIVLGGTT VHNTKSFLEE VLASGLHSRS KESSQVTSRS ASRR

Genular Protein ID: 2568158864

Symbol: A0A2R8YE10_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2R8YE10

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 3 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 534
  • Mass: 61134
  • Checksum: 8FCD506E27D10459
  • Sequence:
    • MVYTQSEILQ KEVYLFERID SQNREIMKHL KAICFLRPTK ENVDYIIQEL RRPKYTIYFI 
YFSNVISKSD VKSLAEADEQ EVVAEVQEFY GDYIAVNPHL FSLNILGCCQ GRNWDPAQLS 
RTTQGLTALL LSLKKCPMIR YQLSSEAAKR LAECVKQVIT KEYELFEFRR TEVPPLLLIL 
DRCDDAITPL LNQWTYQAMV HELLGINNNR IDLSRVPGIS KDLREVVLSA ENDEFYANNM 
YLNFAEIGSN IKNLMEDFQK KKPKEQQKLE SIADMKAFVE NYPQFKKMSG TVSKHVTVVG 
ELSRLVSERN LLEVSEVEQE LACQNDHSSA LQNIKRLLQN PKVTEFDAAR LVMLYALHYE 
RHSSNSLPGL MMDLRNKGVS EKYRKLVSAV VEYGGKRVRG SDLFSPKDAV AITKQFLKGL 
KGVENVYTQH QPFLHETLDH LIKGRLKENL YPYLGPSTLR DRPQDIIVFV IGGATYEEAL 
TVYNLNRTTP GVRIVLGGTT VHNTKSFLEE VLASGLHSRS KESSQVTSRS ASRR

Genular Protein ID: 2630296745

Symbol: B7Z5D4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z5D4

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SUPFAM 1

Sequence Information:

  • Length: 538
  • Mass: 61927
  • Checksum: 30150950C74DA909
  • Sequence:
    • MVYTQSEILQ KEVYLFERID SQNREIMKHL KAICFLRPTK ENVDYIIQEL RRPKYTIYFI 
YFSNVISKSD VKSLAEADEQ EVVAEVQQVI TKEYELFEFR RTEVPPLLLI LDRCDDAITP 
LLNQWTYQAM VHELLGINNN RIDLSRVPGI SKDLREVVLS AENDEFYANN MYLNFAEIGS 
NIKNLMEDFQ KKKPKEQQKL ESIADMKAFV ENYPQFKKMS GTVSKHVTVV GELSRLVSER 
NLLEVSEVEQ ELACQNDHSS ALQNIKRLLQ NPKVTEFDAA RLVMLYALHY ERHSSNCLPG 
LMMDLRNKGV SEKYRKLVSA VVEYGGKRVR GSDLFSPKDA VAITKQFLKG LKGVENVYTQ 
HQPFLHETLD HLIKGRLKGN LYPYLGPSTL RDRPQDIIVF VIGGATYEEA LTVYNLNRTT 
PGVRIVLGGT TVHNTKRDGV SLCSPAWFRT PGLKRSTRLS LPKCWDYSFP RGSSGFWTAQ 
PKQGELSSHI KVSEQKMKRW LGEGHSFLSC PHYRFSLLNK GVGEQLWVLC WLLELISR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.