Details for: ECD

Gene ID: 11319

Symbol: ECD

Ensembl ID: ENSG00000122882

Description: ecdysoneless cell cycle regulator

Associated with

Other Information

Genular Protein ID: 3106121553

Symbol: ECD_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9928932

Title: A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae.

PubMed ID: 9928932

DOI: 10.1007/s004380050926

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16849563

Title: The human orthologue of Drosophila ecdysoneless protein interacts with p53 and regulates its function.

PubMed ID: 16849563

DOI: 10.1158/0008-5472.can-06-0722

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19640839

Title: Role of mammalian Ecdysoneless in cell cycle regulation.

PubMed ID: 19640839

DOI: 10.1074/jbc.m109.030551

PubMed ID: 19919181

Title: Biochemical characterization of human Ecdysoneless reveals a role in transcriptional regulation.

PubMed ID: 19919181

DOI: 10.1515/bc.2010.004

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22270930

Title: Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients.

PubMed ID: 22270930

DOI: 10.1007/s10549-011-1946-8

PubMed ID: 22977192

Title: Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis.

PubMed ID: 22977192

DOI: 10.1158/1078-0432.ccr-12-1789

PubMed ID: 23880345

Title: TXNIP interacts with hEcd to increase p53 stability and activity.

PubMed ID: 23880345

DOI: 10.1016/j.bbrc.2013.07.036

PubMed ID: 24656813

Title: Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex.

PubMed ID: 24656813

DOI: 10.1016/j.celrep.2014.03.013

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24722212

Title: Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing.

PubMed ID: 24722212

DOI: 10.1371/journal.pgen.1004287

PubMed ID: 26711270

Title: A novel interaction of ecdysoneless (ECD) protein with R2TP complex component RUVBL1 is required for the functional role of ECD in cell cycle progression.

PubMed ID: 26711270

DOI: 10.1128/mcb.00594-15

PubMed ID: 11090341

Title: Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23.

PubMed ID: 11090341

DOI: 10.1086/316954

Sequence Information:

  • Length: 644
  • Mass: 72758
  • Checksum: F9B0D2BBFDB38CAF
  • Sequence:
  • MEETMKLATM EDTVEYCLFL IPDESRDSDK HKEILQKYIE RIITRFAPML VPYIWQNQPF 
    NLKYKPGKGG VPAHMFGVTK FGDNIEDEWF IVYVIKQITK EFPELVARIE DNDGEFLLIE 
    AADFLPKWLD PENSTNRVFF CHGELCIIPA PRKSGAESWL PTTPPTIPQA LNIITAHSEK 
    ILASESIRAA VNRRIRGYPE KIQASLHRAH CFLPAGIVAV LKQRPRLVAA AVQAFYLRDP 
    IDLRACRVFK TFLPETRIMT SVTFTKCLYA QLVQQRFVPD RRSGYRLPPP SDPQYRAHEL 
    GMKLAHGFEI LCSKCSPHFS DCKKSLVTAS PLWASFLESL KKNDYFKGLI EGSAQYRERL 
    EMAENYFQLS VDWPESSLAM SPGEEILTLL QTIPFDIEDL KKEAANLPPE DDDQWLDLSP 
    DQLDQLLQEA VGKKESESVS KEEKEQNYDL TEVSESMKAF ISKVSTHKGA ELPREPSEAP 
    ITFDADSFLN YFDKILGPRP NESDSDDLDD EDFECLDSDD DLDFETHEPG EEASLKGTLD 
    NLKSYMAQMD QELAHTCISK SFTTRNQVEP VSQTTDNNSD EEDSGTGESV MAPVDVDLNL 
    VSNILESYSS QAGLAGPASN LLQSMGVQLP DNTDHRPTSK PTKN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.