MGAT4A | ENSG00000071073 | NCBI 11320

Details for: MGAT4A

Gene ID: 11320

Symbol: MGAT4A

Ensembl ID: ENSG00000071073

Description: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Disease
(R-HSA-1643685)
Infectious disease
(R-HSA-5663205)
Late sars-cov-2 infection events
(R-HSA-9772573)
Maturation of spike protein
(R-HSA-9694548)
Metabolism of proteins
(R-HSA-392499)
N-glycan antennae elongation
(R-HSA-975577)
N-glycan antennae elongation in the medial/trans-golgi
(R-HSA-975576)
Post-translational protein modification
(R-HSA-597592)
Post-translational protein phosphorylation
(R-HSA-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-HSA-381426)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov infections
(R-HSA-9679506)
Translation of structural proteins
(R-HSA-9694635)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Viral infection pathways
(R-HSA-9824446)
Acetylglucosaminyltransferase activity
(GO:0008375)
Alanine-glyoxylate transaminase activity
(GO:0008453)
Alpha-1,3-mannosylglycoprotein 4-beta-n-acetylglucosaminyltransferase activity
(GO:0008454)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum-golgi intermediate compartment
(GO:0005793)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular exosome
(GO:0070062)
Glyoxylate metabolic process
(GO:0046487)
Golgi membrane
(GO:0000139)
Golgi stack
(GO:0005795)
Metal ion binding
(GO:0046872)
N-glycan processing
(GO:0006491)
Peroxisome
(GO:0005777)
Protein glycosylation
(GO:0006486)
Protein homodimerization activity
(GO:0042803)
Protein n-linked glycosylation
(GO:0006487)
Viral protein processing
(GO:0019082)

Other Information

Proteins

N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa

Genular Protein ID: 2958112144

Symbol: MGT4A_HUMAN

Name: N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa

UniProtKB Accession Codes:

Q9UM21 B4E2R6 D3DVH6 E9PEN2 Q53S97 Q86Z15

Database IDs:

Citations:

PubMed ID: 10024668

Title: Tissue specific expression and chromosomal mapping of a human UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N-acetylglucosaminyltransferase.

PubMed ID: 10024668

DOI: 10.1093/glycob/9.3.303

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10463590

Title: Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain.

PubMed ID: 10463590

PubMed ID: 16434023

Title: Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer.

PubMed ID: 16434023

DOI: 10.1016/j.bbrc.2005.12.208

PubMed ID: 17006639

Title: Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes.

PubMed ID: 17006639

DOI: 10.1007/s10719-006-6216-3

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

Sequence Information:

Length: 535
Mass: 61544
Checksum: C139E5F323A083A1
Sequence:

MRLRNGTVAT ALAFITSFLT LSWYTTWQNG KEKLIAYQRE FLALKERLRI AEHRISQRSS 
ELNTIVQQFK RVGAETNGSK DALNKFSDNT LKLLKELTSK KSLQVPSIYY HLPHLLKNEG 
SLQPAVQIGN GRTGVSIVMG IPTVKREVKS YLIETLHSLI DNLYPEEKLD CVIVVFIGET 
DIDYVHGVVA NLEKEFSKEI SSGLVEVISP PESYYPDLTN LKETFGDSKE RVRWRTKQNL 
DYCFLMMYAQ EKGIYYIQLE DDIIVKQNYF NTIKNFALQL SSEEWMILEF SQLGFIGKMF 
QAPDLTLIVE FIFMFYKEKP IDWLLDHILW VKVCNPEKDA KHCDRQKANL RIRFRPSLFQ 
HVGLHSSLSG KIQKLTDKDY MKPLLLKIHV NPPAEVSTSL KVYQGHTLEK TYMGEDFFWA 
ITPIAGDYIL FKFDKPVNVE SYLFHSGNQE HPGDILLNTT VEVLPFKSEG LEISKETKDK 
RLEDGYFRIG KFENGVAEGM VDPSLNPISA FRLSVIQNSA VWAILNEIHI KKATN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MGAT4A

Associated with

Other Information

Tissue specific expression and chromosomal mapping of a human UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N-acetylglucosaminyltransferase. PubMed ID: 10024668

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain. PubMed ID: 10463590

Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. PubMed ID: 16434023

Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes. PubMed ID: 17006639

A single kinase generates the majority of the secreted phosphoproteome. PubMed ID: 26091039