VSIG4 | ENSG00000155659 | NCBI 11326

Details for: VSIG4

Gene ID: 11326

Symbol: VSIG4

Ensembl ID: ENSG00000155659

Description: V-set and immunoglobulin domain containing 4

Associated with

Complement activation, alternative pathway
(GO:0006957)
Complement component c3b binding
(GO:0001851)
Membrane
(GO:0016020)
Negative regulation of complement activation, alternative pathway
(GO:0045957)
Negative regulation of interleukin-2 production
(GO:0032703)
Negative regulation of macrophage activation
(GO:0043031)
Negative regulation of t cell proliferation
(GO:0042130)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)

Other Information

Proteins

V-set and immunoglobulin domain-containing protein 4

Genular Protein ID: 3490647059

Symbol: VSIG4_HUMAN

Name: V-set and immunoglobulin domain-containing protein 4

UniProtKB Accession Codes:

Q9Y279 Q6UXI4

Database IDs:

Citations:

PubMed ID: 11004523

Title: Cloning of Z39Ig, a novel gene with immunoglobulin-like domains located on human chromosome X.

PubMed ID: 11004523

DOI: 10.1016/s0167-4781(00)00131-7

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 17016562

Title: VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.

PubMed ID: 17016562

DOI: 10.1172/jci25673

PubMed ID: 17051150

Title: Structure of C3b in complex with CRIg gives insights into regulation of complement activation.

PubMed ID: 17051150

DOI: 10.1038/nature05263

Sequence Information:

Length: 399
Mass: 43987
Checksum: 735CA3BC58185035
Sequence:

MGILLGLLLL GHLTVDTYGR PILEVPESVT GPWKGDVNLP CTYDPLQGYT QVLVKWLVQR 
GSDPVTIFLR DSSGDHIQQA KYQGRLHVSH KVPGDVSLQL STLEMDDRSH YTCEVTWQTP 
DGNQVVRDKI TELRVQKLSV SKPTVTTGSG YGFTVPQGMR ISLQCQARGS PPISYIWYKQ 
QTNNQEPIKV ATLSTLLFKP AVIADSGSYF CTAKGQVGSE QHSDIVKFVV KDSSKLLKTK 
TEAPTTMTYP LKATSTVKQS WDWTTDMDGY LGETSAGPGK SLPVFAIILI ISLCCMVVFT 
MAYIMLCRKT SQQEHVYEAA RAHAREANDS GETMRVAIFA SGCSSDEPTS QNLGNNYSDE 
PCIGQEYQII AQINGNYARL LDTVPLDYEF LATEGKSVC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: VSIG4

Associated with

Other Information

Cloning of Z39Ig, a novel gene with immunoglobulin-like domains located on human chromosome X. PubMed ID: 11004523

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The DNA sequence of the human X chromosome. PubMed ID: 15772651

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Signal peptide prediction based on analysis of experimentally verified cleavage sites. PubMed ID: 15340161

VSIG4, a B7 family-related protein, is a negative regulator of T cell activation. PubMed ID: 17016562

Structure of C3b in complex with CRIg gives insights into regulation of complement activation. PubMed ID: 17051150