Details for: PHB2

Gene ID: 11331

Symbol: PHB2

Ensembl ID: ENSG00000215021

Description: prohibitin 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 4.53
    Marker Score: 3,030
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 4.06
    Marker Score: 2,465
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 3.69
    Marker Score: 7,783
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 3.37
    Marker Score: 3,513
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 3.36
    Marker Score: 2,997
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 3.09
    Marker Score: 2,182
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.89
    Marker Score: 18,798
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.85
    Marker Score: 37,623
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.59
    Marker Score: 3,667
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.52
    Marker Score: 4,393
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.47
    Marker Score: 7,338
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.43
    Marker Score: 6,618
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.42
    Marker Score: 28,125
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.38
    Marker Score: 82,550
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.37
    Marker Score: 1,487
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 2.34
    Marker Score: 31,508
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 2.32
    Marker Score: 1,233
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.31
    Marker Score: 2,170
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.3
    Marker Score: 9,852
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.28
    Marker Score: 4,756
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 2.27
    Marker Score: 664
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.26
    Marker Score: 1,636
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.25
    Marker Score: 14,411
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.25
    Marker Score: 16,729
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.23
    Marker Score: 2,388
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.23
    Marker Score: 22,423
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.23
    Marker Score: 9,120
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 2.22
    Marker Score: 3,644
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 2.2
    Marker Score: 2,214
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 2.19
    Marker Score: 1,222
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.19
    Marker Score: 2,327
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.17
    Marker Score: 73,790
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.16
    Marker Score: 2,033
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.16
    Marker Score: 21,844
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.15
    Marker Score: 24,268
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 2.14
    Marker Score: 3,820
  • Cell Name: centroblast (CL0009112)
    Fold Change: 2.14
    Marker Score: 1,053
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.12
    Marker Score: 112,289
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 2.08
    Marker Score: 2,245
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.07
    Marker Score: 4,867
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.06
    Marker Score: 4,685
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 2.05
    Marker Score: 659
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.05
    Marker Score: 1,739
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 2.05
    Marker Score: 3,476
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.02
    Marker Score: 8,690
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.01
    Marker Score: 1,335
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2
    Marker Score: 2,141
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2
    Marker Score: 8,322
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2
    Marker Score: 7,864
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2
    Marker Score: 1,334
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2
    Marker Score: 6,302
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2
    Marker Score: 1,967
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.99
    Marker Score: 1,197
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.99
    Marker Score: 3,890
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.98
    Marker Score: 1,501
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.98
    Marker Score: 4,710
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.98
    Marker Score: 2,920
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.98
    Marker Score: 1,119
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.97
    Marker Score: 1,155
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.97
    Marker Score: 7,288
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.96
    Marker Score: 5,334
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.96
    Marker Score: 696
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.95
    Marker Score: 1,745
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.95
    Marker Score: 3,240
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 1.95
    Marker Score: 956
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.95
    Marker Score: 3,799
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.95
    Marker Score: 2,059
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.94
    Marker Score: 2,181
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.92
    Marker Score: 1,399
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.89
    Marker Score: 663
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.89
    Marker Score: 1,038
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.88
    Marker Score: 3,945
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.88
    Marker Score: 18,635
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 1.88
    Marker Score: 1,967
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 1.88
    Marker Score: 1,815
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.87
    Marker Score: 987
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.87
    Marker Score: 661
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.86
    Marker Score: 3,185
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.85
    Marker Score: 2,851
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.85
    Marker Score: 695
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.84
    Marker Score: 2,448
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.84
    Marker Score: 8,830
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 1.83
    Marker Score: 436
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.83
    Marker Score: 1,715
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 1.82
    Marker Score: 2,143
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.81
    Marker Score: 2,120
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 1.8
    Marker Score: 1,098
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 1.8
    Marker Score: 4,391
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.8
    Marker Score: 1,692
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.8
    Marker Score: 5,640
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 1.8
    Marker Score: 591
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.79
    Marker Score: 1,214
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.78
    Marker Score: 99,729
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.78
    Marker Score: 3,344
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.78
    Marker Score: 672
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 1.77
    Marker Score: 1,172
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 1.76
    Marker Score: 1,384
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.76
    Marker Score: 2,797
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.75
    Marker Score: 828
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.75
    Marker Score: 1,040

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PHB2 is a small, mitochondrial protein that shares sequence homology with prohibitin, a well-studied protein involved in regulating mitochondrial dynamics and cell cycle progression. PHB2 is highly expressed in various cell types, including skeletal muscle satellite cells, myeloid dendritic cells, and pancreatic acinar cells. Its expression is also observed in hematopoietic cells, including monocytes and B-1 B cells. **Pathways and Functions:** PHB2 is involved in numerous cellular pathways, including: 1. **Cell Cycle Regulation:** PHB2 acts as a negative regulator of the cell cycle, inhibiting the transition from the G1 to the S phase by interacting with and inhibiting the activity of cell cycle regulators, such as cyclin-dependent kinases (CDKs). 2. **Apoptosis Regulation:** PHB2 inhibits apoptosis by interacting with and inhibiting pro-apoptotic proteins, such as Bcl-2 family members. 3. **Immune Response:** PHB2 is involved in the regulation of immune responses, particularly in the context of viral infections. It interacts with and inhibits the activity of protein kinase C (PKC) and phospholipase C (PLC), which are key regulators of immune cell activation. 4. **Mitochondrial Dynamics:** PHB2 regulates mitochondrial dynamics, including mitochondrial fission and fusion, by interacting with and inhibiting the activity of mitochondrial fission factor (MFF) and mitofusin 1 (Mfn1). 5. **Estrogen Signaling:** PHB2 interacts with and inhibits the activity of estrogen receptors, which are key regulators of estrogen signaling pathways. **Clinical Significance:** Dysregulation of PHB2 has been implicated in various diseases, including: 1. **Cancer:** Overexpression of PHB2 has been observed in several types of cancer, including breast, lung, and colon cancer. PHB2 promotes tumorigenesis by inhibiting apoptosis and promoting cell cycle progression. 2. **Autoimmune Diseases:** PHB2 has been implicated in the regulation of immune responses in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. Dysregulation of PHB2 can lead to an imbalance in immune responses, contributing to disease pathogenesis. 3. **Neurodegenerative Diseases:** PHB2 has been implicated in the regulation of mitochondrial function in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Dysregulation of PHB2 can lead to mitochondrial dysfunction, contributing to disease pathogenesis. 4. **Infectious Diseases:** PHB2 has been implicated in the regulation of immune responses in infectious diseases, such as HIV and influenza. Dysregulation of PHB2 can lead to an imbalance in immune responses, contributing to disease pathogenesis. In conclusion, PHB2 is a multifaceted protein that plays a crucial role in regulating various cellular processes, including cell cycle progression, apoptosis, and immune responses. Dysregulation of PHB2 has been implicated in various diseases, highlighting the importance of this protein in maintaining cellular homeostasis and preventing disease. Further research is needed to fully elucidate the mechanisms by which PHB2 regulates cellular processes and to explore its therapeutic potential in various diseases.

Genular Protein ID: 968528418

Symbol: PHB2_HUMAN

Name: Prohibitin-2

UniProtKB Accession Codes:

Q99623 B4DP75 Q2YDA4 Q7KYU3 Q92978

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 CarbonylDB 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 14 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 54 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 1 PRIDE 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9074930

Title: Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.

PubMed ID: 9074930

DOI: 10.1101/gr.7.3.268

PubMed ID: 10359819

Title: An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens.

PubMed ID: 10359819

DOI: 10.1073/pnas.96.12.6947

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11302691

Title: Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.

PubMed ID: 11302691

DOI: 10.1006/excr.2001.5166

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19496786

Title: Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.

PubMed ID: 19496786

DOI: 10.1111/j.1349-7006.2009.01209.x

PubMed ID: 19640993

Title: Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.

PubMed ID: 19640993

DOI: 10.1128/jvi.00842-09

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19906925

Title: Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein.

PubMed ID: 19906925

DOI: 10.1128/jvi.01641-09

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21328542

Title: ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.

PubMed ID: 21328542

DOI: 10.1002/emmm.201100121

PubMed ID: 20959514

Title: Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration.

PubMed ID: 20959514

DOI: 10.1096/fj.10-167502

PubMed ID: 21746876

Title: Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function.

PubMed ID: 21746876

DOI: 10.1128/mcb.05393-11

PubMed ID: 22997079

Title: Identification of prohibitin as a Chikungunya virus receptor protein.

PubMed ID: 22997079

DOI: 10.1002/jmv.23403

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24003225

Title: Prohibitin-2 binding modulates insulin-like growth factor-binding protein-6 (IGFBP-6)-induced rhabdomyosarcoma cell migration.

PubMed ID: 24003225

DOI: 10.1074/jbc.m113.510826

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25904163

Title: Prohibitin 2: At a communications crossroads.

PubMed ID: 25904163

DOI: 10.1002/iub.1366

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28017329

Title: Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.

PubMed ID: 28017329

DOI: 10.1016/j.cell.2016.11.042

PubMed ID: 32276428

Title: Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

PubMed ID: 32276428

DOI: 10.3390/v12040414

PubMed ID: 31522117

Title: Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.

PubMed ID: 31522117

DOI: 10.1016/j.isci.2019.08.056

Sequence Information:

  • Length: 299
  • Mass: 33296
  • Checksum: A887CC982BF85C80
  • Sequence:
    • MAQNLKDLAG RLPAGPRGMG TALKLLLGAG AVAYGVRESV FTVEGGHRAI FFNRIGGVQQ 
DTILAEGLHF RIPWFQYPII YDIRARPRKI SSPTGSKDLQ MVNISLRVLS RPNAQELPSM 
YQRLGLDYEE RVLPSIVNEV LKSVVAKFNA SQLITQRAQV SLLIRRELTE RAKDFSLILD 
DVAITELSFS REYTAAVEAK QVAQQEAQRA QFLVEKAKQE QRQKIVQAEG EAEAAKMLGE 
ALSKNPGYIK LRKIRAAQNI SKTIATSQNR IYLTADNLVL NLQDESFTRG SDSLIKGKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.