Details for: CBX3

Gene ID: 11335

Symbol: CBX3

Ensembl ID: ENSG00000122565

Description: chromobox 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 2.85
    Marker Score: 2,975
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.71
    Marker Score: 3,842
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.55
    Marker Score: 88,206
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 2.54
    Marker Score: 10,606
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 2.5
    Marker Score: 3,855
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 2.49
    Marker Score: 3,580
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 2.47
    Marker Score: 2,775
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 2.46
    Marker Score: 9,530
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.42
    Marker Score: 31,855
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.39
    Marker Score: 2,553
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.38
    Marker Score: 4,962
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 2.38
    Marker Score: 3,265
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.3
    Marker Score: 2,168
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.28
    Marker Score: 6,775
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.26
    Marker Score: 25,406
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.25
    Marker Score: 1,416
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 2.21
    Marker Score: 6,304
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 2.21
    Marker Score: 21,880
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 2.2
    Marker Score: 3,742
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.18
    Marker Score: 6,026
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.16
    Marker Score: 21,858
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 2.15
    Marker Score: 2,169
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.14
    Marker Score: 24,870
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.13
    Marker Score: 3,781
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.13
    Marker Score: 72,515
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.13
    Marker Score: 634
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 2.13
    Marker Score: 1,604
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.12
    Marker Score: 2,252
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.11
    Marker Score: 1,408
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 2.1
    Marker Score: 2,220
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.09
    Marker Score: 53,626
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.09
    Marker Score: 2,227
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 2.08
    Marker Score: 7,684
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.07
    Marker Score: 1,627
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.07
    Marker Score: 4,130
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.07
    Marker Score: 4,863
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.06
    Marker Score: 8,443
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 2.04
    Marker Score: 2,271
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.04
    Marker Score: 488
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.04
    Marker Score: 831
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.03
    Marker Score: 1,480
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.03
    Marker Score: 2,059
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 2.03
    Marker Score: 5,510
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.99
    Marker Score: 995
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.99
    Marker Score: 12,954
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.99
    Marker Score: 2,496
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.98
    Marker Score: 5,393
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.98
    Marker Score: 8,544
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 1.97
    Marker Score: 886
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.95
    Marker Score: 922
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.95
    Marker Score: 5,227
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.95
    Marker Score: 2,280
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.95
    Marker Score: 1,155
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.95
    Marker Score: 108,776
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.94
    Marker Score: 19,536
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 1.94
    Marker Score: 1,030
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.93
    Marker Score: 7,598
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.93
    Marker Score: 10,159
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.93
    Marker Score: 1,217
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.91
    Marker Score: 1,844
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.91
    Marker Score: 550
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.9
    Marker Score: 2,801
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.88
    Marker Score: 3,281
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.87
    Marker Score: 3,349
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.86
    Marker Score: 4,423
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 1.86
    Marker Score: 2,579
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 1.85
    Marker Score: 682
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.84
    Marker Score: 1,987
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.84
    Marker Score: 795
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.84
    Marker Score: 1,150
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.84
    Marker Score: 591
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.84
    Marker Score: 2,446
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.84
    Marker Score: 570
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.83
    Marker Score: 1,314
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 1.83
    Marker Score: 603
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.82
    Marker Score: 686
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.82
    Marker Score: 1,039
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.82
    Marker Score: 1,980
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.82
    Marker Score: 1,621
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.81
    Marker Score: 3,009
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.81
    Marker Score: 477
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.81
    Marker Score: 407
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.8
    Marker Score: 629
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 1.8
    Marker Score: 1,034
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 1.79
    Marker Score: 1,091
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 1.79
    Marker Score: 922
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.79
    Marker Score: 602
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.79
    Marker Score: 94,592
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.79
    Marker Score: 1,353
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.78
    Marker Score: 4,488
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.78
    Marker Score: 2,293
  • Cell Name: oocyte (CL0000023)
    Fold Change: 1.77
    Marker Score: 437
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.77
    Marker Score: 628
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.76
    Marker Score: 4,309
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.76
    Marker Score: 3,312
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 1.76
    Marker Score: 465
  • Cell Name: centroblast (CL0009112)
    Fold Change: 1.75
    Marker Score: 864
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.74
    Marker Score: 409
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.74
    Marker Score: 1,849
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 1.73
    Marker Score: 493

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CBX3 is a member of the Polycomb Group (PcG) family of proteins, which are known for their role in maintaining genome stability and repressing gene expression. The protein consists of a chromobox domain, a histone-binding domain, and a transcriptional repression domain. CBX3 is specifically bound to histone H3 and H4, and its interaction with these histones is crucial for maintaining chromatin structure and transcriptional activity. The protein is also involved in the regulation of DNA damage response, cell cycle progression, and apoptosis. **Pathways and Functions** CBX3 is involved in several key pathways, including: 1. **Chromatin remodeling**: CBX3 interacts with chromatin remodeling enzymes to modulate chromatin structure and transcriptional activity. This interaction is crucial for maintaining genome stability and regulating gene expression. 2. **Epigenetic regulation of gene expression**: CBX3 is involved in the regulation of gene expression through its interaction with epigenetic enzymes, such as histone methyltransferases and histone demethylases. 3. **DNA damage response**: CBX3 is involved in the regulation of DNA damage response, including the repair of DNA double-strand breaks and the maintenance of genome stability. 4. **Cell cycle progression**: CBX3 is involved in the regulation of cell cycle progression, including the G1/S and G2/M phases. 5. **Apoptosis**: CBX3 is involved in the regulation of apoptosis, including the induction of programmed cell death in response to DNA damage. **Clinical Significance** Dysregulation of CBX3 has been implicated in various diseases, including: 1. **Cancer**: CBX3 is often downregulated in cancer cells, leading to the loss of chromatin remodeling and epigenetic regulation. 2. **Neurological disorders**: CBX3 has been implicated in the regulation of gene expression in the nervous system, and its dysregulation has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Immune-related conditions**: CBX3 is involved in the regulation of immune responses, and its dysregulation has been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 4. **Developmental disorders**: CBX3 is involved in the regulation of gene expression during development, and its dysregulation has been linked to developmental disorders, such as Down syndrome and intellectual disability. In conclusion, CBX3 is a critical component of the chromatin remodeling complex that plays a significant role in regulating gene expression and maintaining genome stability. Its dysregulation has been implicated in various diseases, including cancer, neurological disorders, and immune-related conditions. Further research is needed to fully understand the role of CBX3 in human disease and to develop therapeutic strategies to target its dysregulation.

Genular Protein ID: 4136332196

Symbol: CBX3_HUMAN

Name: Chromobox protein homolog 3

UniProtKB Accession Codes:

Q13185 Q96CD7 Q99409 Q9BVS3 Q9P0Z6

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CPTAC 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 6 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8663349

Title: Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1.

PubMed ID: 8663349

DOI: 10.1074/jbc.271.25.14653

PubMed ID: 10664448

Title: Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1.

PubMed ID: 10664448

DOI: 10.1016/s0014-5793(00)01105-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9169472

Title: Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR.

PubMed ID: 9169472

DOI: 10.1074/jbc.272.23.14983

PubMed ID: 9864353

Title: INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1.

PubMed ID: 9864353

DOI: 10.1083/jcb.143.7.1763

PubMed ID: 9636146

Title: Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment.

PubMed ID: 9636146

DOI: 10.1073/pnas.95.13.7316

PubMed ID: 10460410

Title: Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells.

PubMed ID: 10460410

DOI: 10.1007/s004120050372

PubMed ID: 10330177

Title: KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.

PubMed ID: 10330177

DOI: 10.1128/mcb.19.6.4366

PubMed ID: 11242053

Title: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

PubMed ID: 11242053

DOI: 10.1038/35065132

PubMed ID: 12004135

Title: A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells.

PubMed ID: 12004135

DOI: 10.1126/science.1069861

PubMed ID: 15502821

Title: A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

PubMed ID: 15502821

DOI: 10.1038/ncb1187

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20850016

Title: Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

PubMed ID: 20850016

DOI: 10.1016/j.cell.2010.08.020

PubMed ID: 19880879

Title: ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1.

PubMed ID: 19880879

DOI: 10.1074/jbc.m109.065862

PubMed ID: 25750265

Title: Retraction: 'ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1'.

PubMed ID: 25750265

DOI: 10.1074/jbc.a109.065862

PubMed ID: 20562864

Title: Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

PubMed ID: 20562864

DOI: 10.1038/ncb2075

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21346195

Title: Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.

PubMed ID: 21346195

DOI: 10.1091/mbc.e11-01-0009

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23251473

Title: Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis.

PubMed ID: 23251473

DOI: 10.1371/journal.pone.0051258

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23542155

Title: Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway.

PubMed ID: 23542155

DOI: 10.1038/nsmb.2532

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28167679

Title: Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.

PubMed ID: 28167679

DOI: 10.1242/jcs.197236

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28977666

Title: CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

PubMed ID: 28977666

DOI: 10.1093/nar/gkx711

PubMed ID: 32051553

Title: The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.

PubMed ID: 32051553

DOI: 10.1038/s41388-020-1206-7

Sequence Information:

  • Length: 183
  • Mass: 20811
  • Checksum: 5928C63E0C93A76A
  • Sequence:
    • MASNKTTLQK MGKKQNGKSK KVEEAEPEEF VVEKVLDRRV VNGKVEYFLK WKGFTDADNT 
WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA ADKPRGFARG 
LDPERIIGAT DSSGELMFLM KWKDSDEADL VLAKEANMKC PQIVIAFYEE RLTWHSCPED 
EAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.