Details for: U2AF2

Gene ID: 11338

Symbol: U2AF2

Ensembl ID: ENSG00000063244

Description: U2 small nuclear RNA auxiliary factor 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.43
    Marker Score: 1,519
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.38
    Marker Score: 3,755
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.34
    Marker Score: 1,354
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.32
    Marker Score: 3,587
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.31
    Marker Score: 1,645
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.3
    Marker Score: 2,725
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.29
    Marker Score: 3,830
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.28
    Marker Score: 1,697
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.26
    Marker Score: 4,953
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.25
    Marker Score: 1,349
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.24
    Marker Score: 8,043
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.23
    Marker Score: 1,762
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.22
    Marker Score: 307
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.21
    Marker Score: 818
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 1.2
    Marker Score: 900
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.2
    Marker Score: 658
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.19
    Marker Score: 866
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.18
    Marker Score: 2,001
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.18
    Marker Score: 40,035
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.17
    Marker Score: 1,660
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.16
    Marker Score: 1,232
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.16
    Marker Score: 2,431
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.16
    Marker Score: 773
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.15
    Marker Score: 18,033
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.14
    Marker Score: 1,862
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.12
    Marker Score: 11,288
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.1
    Marker Score: 316
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.09
    Marker Score: 4,469
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.09
    Marker Score: 1,893
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.08
    Marker Score: 12,535
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.07
    Marker Score: 6,357
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.07
    Marker Score: 3,953
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 1.06
    Marker Score: 1,103
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.05
    Marker Score: 329
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.04
    Marker Score: 1,063
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 1.03
    Marker Score: 647
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.03
    Marker Score: 967
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.03
    Marker Score: 617
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.02
    Marker Score: 330
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.02
    Marker Score: 957
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.02
    Marker Score: 53,727
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.01
    Marker Score: 324
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.01
    Marker Score: 3,187
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1
    Marker Score: 1,479
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 1
    Marker Score: 734
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1
    Marker Score: 2,348
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,611
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,834
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.99
    Marker Score: 347
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.99
    Marker Score: 13,260
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.98
    Marker Score: 1,051
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,373
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.98
    Marker Score: 4,190
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.98
    Marker Score: 3,065
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.97
    Marker Score: 295
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.97
    Marker Score: 476
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.97
    Marker Score: 227
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.96
    Marker Score: 4,728
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.96
    Marker Score: 12,673
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.96
    Marker Score: 7,119
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.95
    Marker Score: 651
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.95
    Marker Score: 748
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.95
    Marker Score: 228
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.95
    Marker Score: 192
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.95
    Marker Score: 9,597
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.95
    Marker Score: 268
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.94
    Marker Score: 2,230
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.94
    Marker Score: 494
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.94
    Marker Score: 679
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 0.94
    Marker Score: 223
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.94
    Marker Score: 467
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.94
    Marker Score: 623
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,381
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.93
    Marker Score: 1,094
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.93
    Marker Score: 591
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.93
    Marker Score: 979
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.92
    Marker Score: 1,798
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 475
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0.92
    Marker Score: 1,643
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.92
    Marker Score: 10,335
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.92
    Marker Score: 3,956
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 433
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.91
    Marker Score: 2,565
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.9
    Marker Score: 614
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.9
    Marker Score: 935
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.9
    Marker Score: 5,131
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.9
    Marker Score: 443
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.89
    Marker Score: 312
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.89
    Marker Score: 2,674
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.89
    Marker Score: 596
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.89
    Marker Score: 1,230
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.89
    Marker Score: 1,372
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.89
    Marker Score: 537
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.89
    Marker Score: 520
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.89
    Marker Score: 219
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.89
    Marker Score: 367
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.88
    Marker Score: 627
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.88
    Marker Score: 193
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.88
    Marker Score: 49,286
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.88
    Marker Score: 2,195

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** U2AF2 is a small nuclear RNA-binding protein that belongs to the C2H2 zinc finger domain family. It is characterized by its ability to bind to specific RNA sequences, particularly those containing the poly-pyrimidine tract (PPT) motif. U2AF2 is a multifunctional protein that interacts with various components of the spliceosome complex, including the U2 small nuclear RNA (snRNA) and the U2AF complex. Its expression is tissue-specific, with high levels observed in cells involved in hematopoiesis, such as B cells and plasmablasts. **Pathways and Functions:** U2AF2 is involved in several key pathways and functions, including: 1. **RNA Splicing:** U2AF2 plays a crucial role in the regulation of RNA splicing, specifically in the removal of introns and the joining of exons. It binds to the U2 snRNA and recruits the U2AF complex to the splice site, facilitating the splicing reaction. 2. **Spliceosome Assembly:** U2AF2 is a key component of the U2AF complex, which is essential for the assembly of the spliceosome complex. It interacts with other spliceosomal proteins to form a functional complex. 3. **Negative Regulation of RNA Splicing:** U2AF2 acts as a negative regulator of RNA splicing, inhibiting the splicing reaction by binding to the U2 snRNA and preventing the recruitment of the U2AF complex. 4. **Positive Regulation of RNA Splicing:** U2AF2 also acts as a positive regulator of RNA splicing, facilitating the splicing reaction by binding to the U2 snRNA and promoting the recruitment of the U2AF complex. **Clinical Significance:** Dysregulation of U2AF2 has been implicated in various diseases, including: 1. **Cancer:** U2AF2 mutations have been identified in several types of cancer, including breast cancer, lung cancer, and leukemia. These mutations can lead to the overexpression of U2AF2, resulting in aberrant RNA splicing and the production of aberrant proteins. 2. **Neurodegenerative Disorders:** U2AF2 has been implicated in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in the U2AF2 gene have been identified in patients with these disorders, suggesting a role for U2AF2 in the regulation of RNA splicing and the production of aberrant proteins. 3. **Immune System Dysregulation:** U2AF2 is also involved in the regulation of immune responses, and dysregulation of U2AF2 has been implicated in immune system dysregulation, including autoimmune disorders and immunodeficiency diseases. In conclusion, U2AF2 is a critical gene that plays a pivotal role in the regulation of RNA splicing. Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and immune system dysregulation. Further research is needed to fully understand the mechanisms by which U2AF2 regulates RNA splicing and the implications of its dysregulation in human disease.

Genular Protein ID: 2084893903

Symbol: U2AF2_HUMAN

Name: Splicing factor U2AF 65 kDa subunit

UniProtKB Accession Codes:

P26368 Q96HC5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 4 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 50 PDBsum 37 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1538748

Title: Cloning and domain structure of the mammalian splicing factor U2AF.

PubMed ID: 1538748

DOI: 10.1038/355609a0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12176931

Title: Large-scale proteomic analysis of the human spliceosome.

PubMed ID: 12176931

DOI: 10.1101/gr.473902

PubMed ID: 9237760

Title: A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.

PubMed ID: 9237760

DOI: 10.1038/41137

PubMed ID: 9447963

Title: Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.

PubMed ID: 9447963

DOI: 10.1128/mcb.18.2.676

PubMed ID: 10449420

Title: Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly.

PubMed ID: 10449420

DOI: 10.1093/emboj/18.16.4549

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15009664

Title: Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors.

PubMed ID: 15009664

DOI: 10.1046/j.1471-4159.2003.02232.x

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17024186

Title: An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries.

PubMed ID: 17024186

DOI: 10.1038/sj.emboj.7601331

PubMed ID: 17589525

Title: U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.

PubMed ID: 17589525

DOI: 10.1038/nsmb1260

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19641227

Title: Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.

PubMed ID: 19641227

DOI: 10.1074/jbc.m109.036632

PubMed ID: 19470458

Title: The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing.

PubMed ID: 19470458

DOI: 10.1073/pnas.0900342106

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19574390

Title: Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

PubMed ID: 19574390

DOI: 10.1126/science.1175865

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21460037

Title: SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing.

PubMed ID: 21460037

DOI: 10.1101/gad.2002611

PubMed ID: 21536736

Title: The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex.

PubMed ID: 21536736

DOI: 10.1101/gad.2038011

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 27720643

Title: Molecular architecture of SF3b and structural consequences of its cancer-related mutations.

PubMed ID: 27720643

DOI: 10.1016/j.molcel.2016.08.036

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 10449418

Title: Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)).

PubMed ID: 10449418

DOI: 10.1093/emboj/18.16.4523

PubMed ID: 12718882

Title: Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.

PubMed ID: 12718882

DOI: 10.1016/s1097-2765(03)00115-1

PubMed ID: 11551507

Title: A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.

PubMed ID: 11551507

DOI: 10.1016/s0092-8674(01)00480-9

Sequence Information:

  • Length: 475
  • Mass: 53501
  • Checksum: 26AD271CD8FC6211
  • Sequence:
    • MSDFDEFERQ LNENKQERDK ENRHRKRSHS RSRSRDRKRR SRSRDRRNRD QRSASRDRRR 
RSKPLTRGAK EEHGGLIRSP RHEKKKKVRK YWDVPPPGFE HITPMQYKAM QAAGQIPATA 
LLPTMTPDGL AVTPTPVPVV GSQMTRQARR LYVGNIPFGI TEEAMMDFFN AQMRLGGLTQ 
APGNPVLAVQ INQDKNFAFL EFRSVDETTQ AMAFDGIIFQ GQSLKIRRPH DYQPLPGMSE 
NPSVYVPGVV STVVPDSAHK LFIGGLPNYL NDDQVKELLT SFGPLKAFNL VKDSATGLSK 
GYAFCEYVDI NVTDQAIAGL NGMQLGDKKL LVQRASVGAK NATLVSPPST INQTPVTLQV 
PGLMSSQVQM GGHPTEVLCL MNMVLPEELL DDEEYEEIVE DVRDECSKYG LVKSIEIPRP 
VDGVEVPGCG KIFVEFTSVF DCQKAMQGLT GRKFANRVVV TKYCDPDSYH RRDFW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.