Details for: MGLL

Gene ID: 11343

Symbol: MGLL

Ensembl ID: ENSG00000074416

Description: monoglyceride lipase

Associated with

Other Information

Genular Protein ID: 2292719060

Symbol: MGLL_HUMAN

Name: Lysophospholipase homolog

UniProtKB Accession Codes:

Q99685 B3KRC2 B7Z9D1 Q6IBG9 Q96AA5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 90 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 EMBL 13 EPD 1 ESTHER 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 15 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 Rhea 35 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9495531

Title: A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase.

PubMed ID: 9495531

DOI: 10.1016/s0168-1702(97)00122-6

PubMed ID: 11470505

Title: Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene.

PubMed ID: 11470505

DOI: 10.1016/s0378-1119(01)00559-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 19029917

Title: Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.

PubMed ID: 19029917

DOI: 10.1038/nchembio.129

PubMed ID: 20079333

Title: Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.

PubMed ID: 20079333

DOI: 10.1016/j.cell.2009.11.027

PubMed ID: 21049984

Title: Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

PubMed ID: 21049984

DOI: 10.1021/tx1002194

PubMed ID: 22969151

Title: Biochemical and pharmacological characterization of human alpha/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).

PubMed ID: 22969151

DOI: 10.1194/jlr.m030411

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 19957260

Title: Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling.

PubMed ID: 19957260

DOI: 10.1002/cbic.200900621

PubMed ID: 24368842

Title: Mutation of Cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency.

PubMed ID: 24368842

DOI: 10.1124/mol.113.090795

PubMed ID: 19962385

Title: Structural basis for human monoglyceride lipase inhibition.

PubMed ID: 19962385

DOI: 10.1016/j.jmb.2009.11.060

Sequence Information:

  • Length: 303
  • Mass: 33261
  • Checksum: 80E754F126EE64DE
  • Sequence:
    • MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE 
LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG 
HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV LPNLSLGPID 
SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP FLLLQGSADR 
LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV SQRTATAGTA 
SPP

Genular Protein ID: 3152007866

Symbol: A0A0C4DFN3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFN3

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 ESTHER 1 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 3 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 PhylomeDB 1 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 313
  • Mass: 34292
  • Checksum: D5C556E17B55E252
  • Sequence:
    • METGPEDPSS MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG 
AGEHSGRYEE LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD 
YPGLPVFLLG HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV 
LPNLSLGPID SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP 
FLLLQGSADR LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV 
SQRTATAGTA SPP

Genular Protein ID: 1413844812

Symbol: B2ZGL7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2ZGL7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ESTHER 1 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 273
  • Mass: 30118
  • Checksum: 0CCB6780E674D031
  • Sequence:
    • MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE 
LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG 
HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VDIYNSDPLI CRAGLKVCFG 
IQLLNAVSRV ERALPKLTVP FLLLQGSADR LCDSKGAYLL MELAKSQDKT LKIYEGAYHV 
LHKELPEVTN SVFHEINMWV SQRTATAGTA SPP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.