TWF2 | ENSG00000247596 | NCBI 11344

Details for: TWF2

Gene ID: 11344

Symbol: TWF2

Ensembl ID: ENSG00000247596

Description: twinfilin actin binding protein 2

Associated with

Sensory perception
(R-HSA-9709957)
Sensory processing of sound
(R-HSA-9659379)
Sensory processing of sound by inner hair cells of the cochlea
(R-HSA-9662360)
Sensory processing of sound by outer hair cells of the cochlea
(R-HSA-9662361)
Actin filament
(GO:0005884)
Actin filament binding
(GO:0051015)
Actin filament depolymerization
(GO:0030042)
Actin monomer binding
(GO:0003785)
Atp binding
(GO:0005524)
Barbed-end actin filament capping
(GO:0051016)
Cadherin binding
(GO:0045296)
Cell projection organization
(GO:0030030)
Cellular response to growth factor stimulus
(GO:0071363)
Cellular response to retinoic acid
(GO:0071300)
Cytoplasm
(GO:0005737)
Extracellular exosome
(GO:0070062)
Filopodium
(GO:0030175)
Growth cone
(GO:0030426)
Lamellipodium
(GO:0030027)
Myofibril
(GO:0030016)
Negative regulation of actin filament polymerization
(GO:0030837)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Positive regulation of axon extension
(GO:0045773)
Positive regulation of lamellipodium assembly
(GO:0010592)
Positive regulation of neuron projection development
(GO:0010976)
Protein binding
(GO:0005515)
Protein kinase c binding
(GO:0005080)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of lamellipodium assembly
(GO:0010591)
Regulation of microvillus length
(GO:0032532)
Rna binding
(GO:0003723)
Sequestering of actin monomers
(GO:0042989)
Stereocilium
(GO:0032420)

Other Information

Proteins

Twinfilin-2

Genular Protein ID: 1507420428

Symbol: TWF2_HUMAN

Name: Twinfilin-2

UniProtKB Accession Codes:

Q6IBS0 Q9Y3F5

Database IDs:

Citations:

PubMed ID: 10406962

Title: Cloning, expression and characterization of an A6 related protein.

PubMed ID: 10406962

DOI: 10.1046/j.1432-1327.1999.00537.x

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

Length: 349
Mass: 39548
Checksum: 635EF8C04EFCE92B
Sequence:

MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG ASQEPVGRWD QDYDRAVLPL 
LDAQQPCYLL YRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE 
LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF 
PLQPEAQRAL QQLKQKMVNY IQMKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL 
YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFHLE IAKKIEIGDG 
AELTAEFLYD EVHPKQHAFK QAFAKPKGPG GKRGHKRLIR GPGENGDDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TWF2

Associated with

Other Information

Cloning, expression and characterization of an A6 related protein. PubMed ID: 10406962

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Patterns of somatic mutation in human cancer genomes. PubMed ID: 17344846