Details for: GABARAPL2

Gene ID: 11345

Symbol: GABARAPL2

Ensembl ID: ENSG00000034713

Description: GABA type A receptor associated protein like 2

Associated with

Other Information

Genular Protein ID: 3136276755

Symbol: GBRL2_HUMAN

Name: GABA(A) receptor-associated protein-like 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11146101

Title: Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.

PubMed ID: 11146101

DOI: 10.1016/s0169-328x(00)00218-7

PubMed ID: 11414770

Title: Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.

PubMed ID: 11414770

DOI: 10.1006/geno.2001.6555

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11096062

Title: The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.

PubMed ID: 11096062

DOI: 10.1074/jbc.c000752200

PubMed ID: 11825910

Title: Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.

PubMed ID: 11825910

DOI: 10.1074/jbc.m200385200

PubMed ID: 12507496

Title: GATE-16 and GABARAP are authentic modifiers mediated by Apg7 and Apg3.

PubMed ID: 12507496

DOI: 10.1016/s0006-291x(02)02907-8

PubMed ID: 15169837

Title: LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

PubMed ID: 15169837

DOI: 10.1242/jcs.01131

PubMed ID: 17580304

Title: p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.

PubMed ID: 17580304

DOI: 10.1074/jbc.m702824200

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19056683

Title: The TP53INP2 protein is required for autophagy in mammalian cells.

PubMed ID: 19056683

DOI: 10.1091/mbc.e08-07-0671

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20818167

Title: Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4).

PubMed ID: 20818167

DOI: 10.4161/auto.6.7.13075

PubMed ID: 20418806

Title: LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis.

PubMed ID: 20418806

DOI: 10.1038/emboj.2010.74

PubMed ID: 20562859

Title: Network organization of the human autophagy system.

PubMed ID: 20562859

DOI: 10.1038/nature09204

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21383079

Title: OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.

PubMed ID: 21383079

DOI: 10.1083/jcb.201008107

PubMed ID: 22421968

Title: TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.

PubMed ID: 22421968

DOI: 10.1038/cdd.2012.30

PubMed ID: 23043107

Title: ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

PubMed ID: 23043107

DOI: 10.1074/jbc.m112.378109

PubMed ID: 22354992

Title: Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

PubMed ID: 22354992

DOI: 10.1128/mcb.06717-11

PubMed ID: 22311637

Title: Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.

PubMed ID: 22311637

DOI: 10.1074/mcp.m111.014035

PubMed ID: 22470510

Title: DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.

PubMed ID: 22470510

DOI: 10.1371/journal.pone.0034034

PubMed ID: 23209295

Title: Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis.

PubMed ID: 23209295

DOI: 10.1074/jbc.m112.399345

PubMed ID: 24089205

Title: Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.

PubMed ID: 24089205

DOI: 10.1038/nature12606

PubMed ID: 25127057

Title: TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.

PubMed ID: 25127057

DOI: 10.1016/j.devcel.2014.06.013

PubMed ID: 24668264

Title: Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.

PubMed ID: 24668264

DOI: 10.1002/embr.201338003

PubMed ID: 26347139

Title: TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.

PubMed ID: 26347139

DOI: 10.1083/jcb.201503023

PubMed ID: 25684205

Title: CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.

PubMed ID: 25684205

DOI: 10.1016/j.molcel.2014.12.040

PubMed ID: 26929408

Title: Structural and functional analysis of a novel interaction motif within UFM1-activating enzyme 5 (UBA5) required for binding to ubiquitin-like proteins and ufmylation.

PubMed ID: 26929408

DOI: 10.1074/jbc.m116.715474

PubMed ID: 29458288

Title: Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.

PubMed ID: 29458288

DOI: 10.1080/15548627.2018.1437341

PubMed ID: 29420192

Title: Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

PubMed ID: 29420192

DOI: 10.1083/jcb.201708039

PubMed ID: 30661429

Title: Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.

PubMed ID: 30661429

DOI: 10.1080/15548627.2019.1569925

PubMed ID: 31722778

Title: LIR motifs and the membrane-targeting domain are complementary in the function of RavZ.

PubMed ID: 31722778

DOI: 10.5483/bmbrep.2019.52.12.211

PubMed ID: 32315611

Title: A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.

PubMed ID: 32315611

DOI: 10.1016/j.devcel.2020.03.018

PubMed ID: 31709703

Title: TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease.

PubMed ID: 31709703

DOI: 10.15252/embr.201948317

PubMed ID: 34338405

Title: Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.

PubMed ID: 34338405

DOI: 10.15252/embr.202052289

PubMed ID: 33909989

Title: Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine.

PubMed ID: 33909989

DOI: 10.1016/j.molcel.2021.03.020

PubMed ID: 30990354

Title: An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.

PubMed ID: 30990354

DOI: 10.1080/15548627.2019.1606637

Sequence Information:

  • Length: 117
  • Mass: 13667
  • Checksum: 17ACB540FD5B975B
  • Sequence:
  • MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF 
    MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.