Details for: CHRNA4

Gene ID: 1137

Symbol: CHRNA4

Ensembl ID: ENSG00000101204

Description: cholinergic receptor nicotinic alpha 4 subunit

Associated with

Other Information

Genular Protein ID: 3668001480

Symbol: ACHA4_HUMAN

Name: Neuronal acetylcholine receptor subunit alpha-4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7721089

Title: Cloning and transient expression of genes encoding the human alpha-4 and beta-2 neuronal nicotinic acetylcholine receptor (nAChR) subunits.

PubMed ID: 7721089

DOI: 10.1016/0378-1119(94)00914-e

PubMed ID: 8833159

Title: Exon-intron structure of the human neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4).

PubMed ID: 8833159

DOI: 10.1006/geno.1996.0119

PubMed ID: 8906617

Title: Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

PubMed ID: 8906617

DOI: 10.1007/bf02736842

PubMed ID: 9009220

Title: Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.

PubMed ID: 9009220

DOI: 10.1016/s0014-5793(96)01383-x

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16120769

Title: RIC-3 enhances functional expression of multiple nicotinic acetylcholine receptor subtypes in mammalian cells.

PubMed ID: 16120769

DOI: 10.1124/mol.105.017459

PubMed ID: 27344019

Title: Functional interaction between Lypd6 and nicotinic acetylcholine receptors.

PubMed ID: 27344019

DOI: 10.1111/jnc.13718

PubMed ID: 22361591

Title: NMR structures of the transmembrane domains of the alpha4beta2 nAChR.

PubMed ID: 22361591

DOI: 10.1016/j.bbamem.2012.02.008

PubMed ID: 7550350

Title: A missense mutation in the neuronal nicotinic acetylcholine receptor alpha-4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy.

PubMed ID: 7550350

DOI: 10.1038/ng1095-201

PubMed ID: 10563623

Title: A novel mutation of CHRNA4 responsible for autosomal dominant nocturnal frontal lobe epilepsy.

PubMed ID: 10563623

DOI: 10.1212/wnl.53.8.1749

PubMed ID: 14623738

Title: A Korean kindred with autosomal dominant nocturnal frontal lobe epilepsy and mental retardation.

PubMed ID: 14623738

DOI: 10.1001/archneur.60.11.1625

Sequence Information:

  • Length: 627
  • Mass: 69957
  • Checksum: B3A0C0151E5A2AA8
  • Sequence:
  • MELGGPGAPR LLPPLLLLLG TGLLRASSHV ETRAHAEERL LKKLFSGYNK WSRPVANISD 
    VVLVRFGLSI AQLIDVDEKN QMMTTNVWVK QEWHDYKLRW DPADYENVTS IRIPSELIWR 
    PDIVLYNNAD GDFAVTHLTK AHLFHDGRVQ WTPPAIYKSS CSIDVTFFPF DQQNCTMKFG 
    SWTYDKAKID LVNMHSRVDQ LDFWESGEWV IVDAVGTYNT RKYECCAEIY PDITYAFVIR 
    RLPLFYTINL IIPCLLISCL TVLVFYLPSE CGEKITLCIS VLLSLTVFLL LITEIIPSTS 
    LVIPLIGEYL LFTMIFVTLS IVITVFVLNV HHRSPRTHTM PTWVRRVFLD IVPRLLLMKR 
    PSVVKDNCRR LIESMHKMAS APRFWPEPEG EPPATSGTQS LHPPSPSFCV PLDVPAEPGP 
    SCKSPSDQLP PQQPLEAEKA SPHPSPGPCR PPHGTQAPGL AKARSLSVQH MSSPGEAVEG 
    GVRCRSRSIQ YCVPRDDAAP EADGQAAGAL ASRNTHSAEL PPPDQPSPCK CTCKKEPSSV 
    SPSATVKTRS TKAPPPHLPL SPALTRAVEG VQYIADHLKA EDTDFSVKED WKYVAMVIDR 
    IFLWMFIIVC LLGTVGLFLP PWLAGMI

Genular Protein ID: 209298424

Symbol: Q59FV0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 533
  • Mass: 58869
  • Checksum: 1939A02DBF569C5A
  • Sequence:
  • APEPGEAPRL DRAHPGCACA ELSLLWLCCC TFTSADGDFA VTHLTKAHLF HDGRVQWTPP 
    AIYKSSCSID VTFFPFDQQN CTMKFGSWTY DKAKIDLVNM HSRVDQLDFW ESGEWVIVDA 
    VGTYNTRKYE CCAEIYPDIT YAFVIRRLPL FYTINLIIPC LLISCLTVLV FYLPSECGEK 
    ITLCISVLLS LTVFLLLITE IIPSTSLVIP LIGEYLLFTM IFVTLSIVIT VFVLNVHHRS 
    PRTHTMPTWV RRVFLDIVPR LLLMKRPSVV KDNCRRLIES MHKMASAPRF WPEPEGEPPA 
    TSGTQSLHPP SPSFCVPLDV PAEPGPSCKS PSDQLPPQQP LEAEKASPHP SPGPCRPPHG 
    TQAPGLAKAR SLSVQHMSSP GEAVEGGVRC RSRSIQYCVP RDDAAPEADG QAAGALASRN 
    THSAELPPPD QPSPCKCTCK KEPSSVSPSA TVKTRSTKAP PPHLPLSPAL TRAVEGVQYI 
    ADHLKAEDTD FSVKEDWKYV AMVIDRIFLW MFIIVCLLGT VGLFLPPWLA GMI

Genular Protein ID: 1212308056

Symbol: B4DK78_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 216
  • Mass: 22757
  • Checksum: 388663C659882EED
  • Sequence:
  • MHMQEGALFG VPECHGQDPQ HQSTAPAPAP VAGPDPGGGG RPVHCRPPEG RRHRLLGEGG 
    LEVRGHGHRP HLPLDVHHRL PAGDGGPLPA ALAGWHDLGR DREPAWPGAA VHGASIHAAG 
    LGPGWLLPGL CGATRLPNFP SCSVSAVRRP WTGTRPLGRP SVELLPVGLW PQEAVAWSRG 
    GGRRLLPAGL GLSPVQESPE LPCRWNSLLP VSQQIW

Genular Protein ID: 4102445759

Symbol: Q4VAQ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 451
  • Mass: 49872
  • Checksum: 43355984FB7B5383
  • Sequence:
  • MKFGSWTYDK AKIDLVNMHS RVDQLDFWES GEWVIVDAVG TYNTRKYECC AEIYPDITYA 
    FVIRRLPLFY TINLIIPCLL ISCLTVLVFY LPSECGEKIT LCISVLLSLT VFLLLITEII 
    PSTSLVIPLI GEYLLFTMIF VTLSIVITVF VLNVHHRSPR THTMPTWVRR VFLDIVPRLL 
    LMKRPSVVKD NCRRLIESMH KMASAPRFWP EPEGEPPATS GTQSLHPPSP SFCVPLDVPA 
    EPGPSCKSPS DQLPPQQPLE AEKASPHPSP GPCRPPHGTQ APGLAKARSL SVQHMSSPGE 
    AVEGGVRCRS RSIQYCVPRD DAAPEADGQA AGALASRNTH SAELPPPDQP SPCKCTCKKE 
    PSSVSPSATV KTRSTKAPPP HLPLSPALTR AVEGVQYIAD HLKAEDTDFS VKEDWKYVAM 
    VIDRIFLWMF IIVCLLGTVG LFLPPWLAGM I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.