Details for: CHRNA4

Gene ID: 1137

Symbol: CHRNA4

Ensembl ID: ENSG00000101204

Description: cholinergic receptor nicotinic alpha 4 subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.4467
    Cell Significance Index: 703.9800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4941
    Cell Significance Index: 10.8200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.4052
    Cell Significance Index: 9.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3188
    Cell Significance Index: 114.3300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1762
    Cell Significance Index: 9.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1431
    Cell Significance Index: 28.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1028
    Cell Significance Index: 20.4100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0306
    Cell Significance Index: 0.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0144
    Cell Significance Index: 9.9900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0001
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0049
    Cell Significance Index: -9.3200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0061
    Cell Significance Index: -9.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0076
    Cell Significance Index: -10.2700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0085
    Cell Significance Index: -5.4200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0123
    Cell Significance Index: -9.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0146
    Cell Significance Index: -10.6900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0155
    Cell Significance Index: -8.7400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0181
    Cell Significance Index: -9.8700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0235
    Cell Significance Index: -10.6700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0422
    Cell Significance Index: -0.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0453
    Cell Significance Index: -9.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0556
    Cell Significance Index: -9.5000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0568
    Cell Significance Index: -3.5800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0632
    Cell Significance Index: -0.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0656
    Cell Significance Index: -4.0300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0676
    Cell Significance Index: -9.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0720
    Cell Significance Index: -10.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0789
    Cell Significance Index: -9.1900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0845
    Cell Significance Index: -1.3400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0852
    Cell Significance Index: -5.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1018
    Cell Significance Index: -10.4000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1192
    Cell Significance Index: -1.1300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1205
    Cell Significance Index: -3.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1247
    Cell Significance Index: -7.0000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1288
    Cell Significance Index: -2.1700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1354
    Cell Significance Index: -1.5800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1530
    Cell Significance Index: -3.3100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1554
    Cell Significance Index: -9.5300
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1724
    Cell Significance Index: -2.0900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1793
    Cell Significance Index: -4.3000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1823
    Cell Significance Index: -2.6900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1872
    Cell Significance Index: -6.1300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1915
    Cell Significance Index: -6.1000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2017
    Cell Significance Index: -10.5100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2054
    Cell Significance Index: -1.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2075
    Cell Significance Index: -9.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2087
    Cell Significance Index: -4.1900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2095
    Cell Significance Index: -7.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2262
    Cell Significance Index: -10.6300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2265
    Cell Significance Index: -5.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2326
    Cell Significance Index: -6.3300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2453
    Cell Significance Index: -9.2900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.2668
    Cell Significance Index: -3.4600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2803
    Cell Significance Index: -9.7400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2837
    Cell Significance Index: -5.6100
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.3089
    Cell Significance Index: -6.0800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3163
    Cell Significance Index: -6.6200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3239
    Cell Significance Index: -6.7600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3256
    Cell Significance Index: -9.3800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.3281
    Cell Significance Index: -4.1400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3291
    Cell Significance Index: -10.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3402
    Cell Significance Index: -7.2200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3431
    Cell Significance Index: -5.8800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3500
    Cell Significance Index: -10.3100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3656
    Cell Significance Index: -10.4800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3678
    Cell Significance Index: -9.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3761
    Cell Significance Index: -9.8900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3766
    Cell Significance Index: -10.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3842
    Cell Significance Index: -10.2600
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.3903
    Cell Significance Index: -4.9000
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.3912
    Cell Significance Index: -7.8000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3916
    Cell Significance Index: -6.7500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.3984
    Cell Significance Index: -5.2100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.4047
    Cell Significance Index: -3.4400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4057
    Cell Significance Index: -9.9000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.4061
    Cell Significance Index: -3.1300
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.4147
    Cell Significance Index: -4.3200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.4265
    Cell Significance Index: -5.5100
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.4443
    Cell Significance Index: -6.3200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.4475
    Cell Significance Index: -5.6700
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.4507
    Cell Significance Index: -3.4500
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.4536
    Cell Significance Index: -6.2200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4615
    Cell Significance Index: -7.9800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.4644
    Cell Significance Index: -7.4500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.4691
    Cell Significance Index: -7.8900
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.4691
    Cell Significance Index: -5.3000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4698
    Cell Significance Index: -9.5600
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.4780
    Cell Significance Index: -5.7700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4787
    Cell Significance Index: -11.0600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4788
    Cell Significance Index: -5.9700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.4791
    Cell Significance Index: -5.7300
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.4811
    Cell Significance Index: -6.2300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4926
    Cell Significance Index: -10.5300
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.4940
    Cell Significance Index: -7.0200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.4961
    Cell Significance Index: -6.8800
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.4962
    Cell Significance Index: -6.0400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.5029
    Cell Significance Index: -12.5600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5121
    Cell Significance Index: -8.5700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.5134
    Cell Significance Index: -6.4800
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.5222
    Cell Significance Index: -5.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Gene structure:** The CHRNA4 gene is a single-copy gene located on chromosome 15q24.3. 2. **Protein structure:** The alpha-4 subunit of the CHRNA4 gene is a transmembrane protein that forms a channel complex with other subunits to create a functional nAChR. 3. **Expression:** The CHRNA4 gene is highly expressed in various cell types, including neurons, immune cells, and epithelial cells. 4. **Function:** The alpha-4 subunit of the CHRNA4 gene is essential for the proper functioning of nAChRs, which are involved in neurotransmission, synaptic plasticity, and immune responses. **Pathways and Functions:** 1. **Acetylcholine-gated channel complex:** The CHRNA4 gene is part of the acetylcholine-gated channel complex, which is a type of nAChR that responds to acetylcholine. 2. **Acetylcholine binding:** The alpha-4 subunit of the CHRNA4 gene is involved in the binding of acetylcholine to the nAChR, which triggers the opening of the channel complex. 3. **Signal transduction:** The activation of nAChRs by acetylcholine triggers a series of downstream signaling events, including the activation of G-proteins and the modulation of neurotransmitter release. 4. **Immune responses:** The CHRNA4 gene is also involved in immune responses, including the activation of B cells and the regulation of dopamine secretion. **Clinical Significance:** 1. **Nicotine addiction:** The CHRNA4 gene is a key target for nicotine addiction, as it plays a crucial role in the development of nicotine dependence. 2. **Neurodegenerative diseases:** The CHRNA4 gene has been implicated in various neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, where nAChRs are thought to play a key role in disease progression. 3. **Immune system disorders:** The CHRNA4 gene is also involved in immune system disorders, including autoimmune diseases and allergies, where nAChRs are thought to play a key role in immune regulation. 4. **Cancer:** The CHRNA4 gene has been implicated in cancer, where nAChRs are thought to play a key role in tumor growth and metastasis. In conclusion, the CHRNA4 gene is a critical component of nicotinic acetylcholine receptors, which are involved in various physiological processes, including neurotransmission, synaptic plasticity, and immune responses. The clinical significance of the CHRNA4 gene is vast, with implications for nicotine addiction, neurodegenerative diseases, immune system disorders, and cancer. Further research is needed to fully understand the role of the CHRNA4 gene in human health and disease.

Genular Protein ID: 3668001480

Symbol: ACHA4_HUMAN

Name: Neuronal acetylcholine receptor subunit alpha-4

UniProtKB Accession Codes:

P43681 Q4JGR7 Q4VAQ5 Q4VAQ6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ComplexPortal 4 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 42 DrugCentral 1 EMBL 14 EMDB 10 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 33 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7721089

Title: Cloning and transient expression of genes encoding the human alpha-4 and beta-2 neuronal nicotinic acetylcholine receptor (nAChR) subunits.

PubMed ID: 7721089

DOI: 10.1016/0378-1119(94)00914-e

PubMed ID: 8833159

Title: Exon-intron structure of the human neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4).

PubMed ID: 8833159

DOI: 10.1006/geno.1996.0119

PubMed ID: 8906617

Title: Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

PubMed ID: 8906617

DOI: 10.1007/bf02736842

PubMed ID: 9009220

Title: Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.

PubMed ID: 9009220

DOI: 10.1016/s0014-5793(96)01383-x

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16120769

Title: RIC-3 enhances functional expression of multiple nicotinic acetylcholine receptor subtypes in mammalian cells.

PubMed ID: 16120769

DOI: 10.1124/mol.105.017459

PubMed ID: 27344019

Title: Functional interaction between Lypd6 and nicotinic acetylcholine receptors.

PubMed ID: 27344019

DOI: 10.1111/jnc.13718

PubMed ID: 22361591

Title: NMR structures of the transmembrane domains of the alpha4beta2 nAChR.

PubMed ID: 22361591

DOI: 10.1016/j.bbamem.2012.02.008

PubMed ID: 7550350

Title: A missense mutation in the neuronal nicotinic acetylcholine receptor alpha-4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy.

PubMed ID: 7550350

DOI: 10.1038/ng1095-201

PubMed ID: 10563623

Title: A novel mutation of CHRNA4 responsible for autosomal dominant nocturnal frontal lobe epilepsy.

PubMed ID: 10563623

DOI: 10.1212/wnl.53.8.1749

PubMed ID: 14623738

Title: A Korean kindred with autosomal dominant nocturnal frontal lobe epilepsy and mental retardation.

PubMed ID: 14623738

DOI: 10.1001/archneur.60.11.1625

Sequence Information:

  • Length: 627
  • Mass: 69957
  • Checksum: B3A0C0151E5A2AA8
  • Sequence:
    • MELGGPGAPR LLPPLLLLLG TGLLRASSHV ETRAHAEERL LKKLFSGYNK WSRPVANISD 
VVLVRFGLSI AQLIDVDEKN QMMTTNVWVK QEWHDYKLRW DPADYENVTS IRIPSELIWR 
PDIVLYNNAD GDFAVTHLTK AHLFHDGRVQ WTPPAIYKSS CSIDVTFFPF DQQNCTMKFG 
SWTYDKAKID LVNMHSRVDQ LDFWESGEWV IVDAVGTYNT RKYECCAEIY PDITYAFVIR 
RLPLFYTINL IIPCLLISCL TVLVFYLPSE CGEKITLCIS VLLSLTVFLL LITEIIPSTS 
LVIPLIGEYL LFTMIFVTLS IVITVFVLNV HHRSPRTHTM PTWVRRVFLD IVPRLLLMKR 
PSVVKDNCRR LIESMHKMAS APRFWPEPEG EPPATSGTQS LHPPSPSFCV PLDVPAEPGP 
SCKSPSDQLP PQQPLEAEKA SPHPSPGPCR PPHGTQAPGL AKARSLSVQH MSSPGEAVEG 
GVRCRSRSIQ YCVPRDDAAP EADGQAAGAL ASRNTHSAEL PPPDQPSPCK CTCKKEPSSV 
SPSATVKTRS TKAPPPHLPL SPALTRAVEG VQYIADHLKA EDTDFSVKED WKYVAMVIDR 
IFLWMFIIVC LLGTVGLFLP PWLAGMI

Genular Protein ID: 4102445759

Symbol: Q4VAQ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q4VAQ3

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 3 GO 6 Gene3D 2 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 RefSeq 2 SAM 2 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 451
  • Mass: 49872
  • Checksum: 43355984FB7B5383
  • Sequence:
    • MKFGSWTYDK AKIDLVNMHS RVDQLDFWES GEWVIVDAVG TYNTRKYECC AEIYPDITYA 
FVIRRLPLFY TINLIIPCLL ISCLTVLVFY LPSECGEKIT LCISVLLSLT VFLLLITEII 
PSTSLVIPLI GEYLLFTMIF VTLSIVITVF VLNVHHRSPR THTMPTWVRR VFLDIVPRLL 
LMKRPSVVKD NCRRLIESMH KMASAPRFWP EPEGEPPATS GTQSLHPPSP SFCVPLDVPA 
EPGPSCKSPS DQLPPQQPLE AEKASPHPSP GPCRPPHGTQ APGLAKARSL SVQHMSSPGE 
AVEGGVRCRS RSIQYCVPRD DAAPEADGQA AGALASRNTH SAELPPPDQP SPCKCTCKKE 
PSSVSPSATV KTRSTKAPPP HLPLSPALTR AVEGVQYIAD HLKAEDTDFS VKEDWKYVAM 
VIDRIFLWMF IIVCLLGTVG LFLPPWLAGM I

Genular Protein ID: 209298424

Symbol: Q59FV0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FV0

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 4 ProteomicsDB 1 RefSeq 2 RuleBase 1 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 533
  • Mass: 58869
  • Checksum: 1939A02DBF569C5A
  • Sequence:
    • APEPGEAPRL DRAHPGCACA ELSLLWLCCC TFTSADGDFA VTHLTKAHLF HDGRVQWTPP 
AIYKSSCSID VTFFPFDQQN CTMKFGSWTY DKAKIDLVNM HSRVDQLDFW ESGEWVIVDA 
VGTYNTRKYE CCAEIYPDIT YAFVIRRLPL FYTINLIIPC LLISCLTVLV FYLPSECGEK 
ITLCISVLLS LTVFLLLITE IIPSTSLVIP LIGEYLLFTM IFVTLSIVIT VFVLNVHHRS 
PRTHTMPTWV RRVFLDIVPR LLLMKRPSVV KDNCRRLIES MHKMASAPRF WPEPEGEPPA 
TSGTQSLHPP SPSFCVPLDV PAEPGPSCKS PSDQLPPQQP LEAEKASPHP SPGPCRPPHG 
TQAPGLAKAR SLSVQHMSSP GEAVEGGVRC RSRSIQYCVP RDDAAPEADG QAAGALASRN 
THSAELPPPD QPSPCKCTCK KEPSSVSPSA TVKTRSTKAP PPHLPLSPAL TRAVEGVQYI 
ADHLKAEDTD FSVKEDWKYV AMVIDRIFLW MFIIVCLLGT VGLFLPPWLA GMI

Genular Protein ID: 1212308056

Symbol: B4DK78_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DK78

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 RefSeq 2 SAM 1

Sequence Information:

  • Length: 216
  • Mass: 22757
  • Checksum: 388663C659882EED
  • Sequence:
    • MHMQEGALFG VPECHGQDPQ HQSTAPAPAP VAGPDPGGGG RPVHCRPPEG RRHRLLGEGG 
LEVRGHGHRP HLPLDVHHRL PAGDGGPLPA ALAGWHDLGR DREPAWPGAA VHGASIHAAG 
LGPGWLLPGL CGATRLPNFP SCSVSAVRRP WTGTRPLGRP SVELLPVGLW PQEAVAWSRG 
GGRRLLPAGL GLSPVQESPE LPCRWNSLLP VSQQIW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.