Details for: CHRNA5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 39.0883
Cell Significance Index: -6.0800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 22.2754
Cell Significance Index: -5.6500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 13.1198
Cell Significance Index: -5.3300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 4.9556
Cell Significance Index: -6.1100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 1.1508
Cell Significance Index: 8.8700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1456
Cell Significance Index: 113.3300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7874
Cell Significance Index: 711.0000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7731
Cell Significance Index: 46.4100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7676
Cell Significance Index: 83.4900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6432
Cell Significance Index: 104.6100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 0.4798
Cell Significance Index: -1.0500 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.4457
Cell Significance Index: 4.8300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3933
Cell Significance Index: 20.4300 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.3924
Cell Significance Index: 4.9700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3906
Cell Significance Index: 27.0200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.3774
Cell Significance Index: 21.1800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3748
Cell Significance Index: 13.1700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.3544
Cell Significance Index: 8.8600 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.3200
Cell Significance Index: 8.1800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3145
Cell Significance Index: 9.0600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.3124
Cell Significance Index: 6.8400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.2473
Cell Significance Index: 5.1300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2227
Cell Significance Index: 42.3900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2146
Cell Significance Index: 4.5700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1809
Cell Significance Index: 3.9200 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.1640
Cell Significance Index: 4.0900 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.1585
Cell Significance Index: 2.2300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1406
Cell Significance Index: 27.9000 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.1377
Cell Significance Index: 1.1700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1372
Cell Significance Index: 6.2200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1305
Cell Significance Index: 1.7800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.1297
Cell Significance Index: 1.4100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1108
Cell Significance Index: 2.3200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1084
Cell Significance Index: 3.0300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0801
Cell Significance Index: 14.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0684
Cell Significance Index: 37.3700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0607
Cell Significance Index: 1.0400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0448
Cell Significance Index: 8.9900 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.0402
Cell Significance Index: 0.5700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.0357
Cell Significance Index: 1.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0350
Cell Significance Index: 15.4900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0310
Cell Significance Index: 3.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0243
Cell Significance Index: 8.7100 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.0152
Cell Significance Index: 0.0900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0130
Cell Significance Index: 0.8000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0105
Cell Significance Index: 0.2700 - Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
Fold Change: 0.0066
Cell Significance Index: 0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0043
Cell Significance Index: 8.1800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0028
Cell Significance Index: 1.8000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0013
Cell Significance Index: 0.5800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0013
Cell Significance Index: 0.0900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0006
Cell Significance Index: -0.0200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0023
Cell Significance Index: -4.2800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0026
Cell Significance Index: -4.0600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0037
Cell Significance Index: -0.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0044
Cell Significance Index: -6.0100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0051
Cell Significance Index: -1.4700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0064
Cell Significance Index: -4.7100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0067
Cell Significance Index: -3.7900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0071
Cell Significance Index: -0.8400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0074
Cell Significance Index: -5.5700 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0089
Cell Significance Index: -0.0600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0098
Cell Significance Index: -6.1500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0105
Cell Significance Index: -1.3400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0136
Cell Significance Index: -0.8600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0148
Cell Significance Index: -1.1400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0149
Cell Significance Index: -2.1600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0157
Cell Significance Index: -0.9600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0218
Cell Significance Index: -2.5400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0232
Cell Significance Index: -0.6200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0238
Cell Significance Index: -0.2700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0247
Cell Significance Index: -1.1500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0248
Cell Significance Index: -3.4100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0320
Cell Significance Index: -6.7400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0322
Cell Significance Index: -3.2900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0325
Cell Significance Index: -4.2000 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.0354
Cell Significance Index: -0.2300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0408
Cell Significance Index: -1.1100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0499
Cell Significance Index: -5.7200 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: -0.0506
Cell Significance Index: -0.4100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0508
Cell Significance Index: -0.8500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0538
Cell Significance Index: -0.7700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0555
Cell Significance Index: -5.7800 - Cell Name: glioblast (CL0000030)
Fold Change: -0.0557
Cell Significance Index: -0.3500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0626
Cell Significance Index: -2.9400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0635
Cell Significance Index: -4.2700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0655
Cell Significance Index: -1.7600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0708
Cell Significance Index: -5.2800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0728
Cell Significance Index: -3.7900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0740
Cell Significance Index: -5.8600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0854
Cell Significance Index: -5.5100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0970
Cell Significance Index: -2.5500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0987
Cell Significance Index: -5.1800 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.1035
Cell Significance Index: -1.2600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1051
Cell Significance Index: -4.6500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1299
Cell Significance Index: -4.9200 - Cell Name: myometrial cell (CL0002366)
Fold Change: -0.1311
Cell Significance Index: -1.5100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1317
Cell Significance Index: -3.7800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1343
Cell Significance Index: -3.2200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1448
Cell Significance Index: -4.7400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2245861410
Symbol: ACHA5_HUMAN
Name: Neuronal acetylcholine receptor subunit alpha-5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1542648
Title: Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines.
PubMed ID: 1542648
PubMed ID: 8906617
Title: Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.
PubMed ID: 8906617
DOI: 10.1007/bf02736842
PubMed ID: 9009220
Title: Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.
PubMed ID: 9009220
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18385720
PubMed ID: 18385738
Title: A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
PubMed ID: 18385738
DOI: 10.1038/nature06885
PubMed ID: 18385676
Title: Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
PubMed ID: 18385676
DOI: 10.1038/ng.109
PubMed ID: 27344019
Title: Functional interaction between Lypd6 and nicotinic acetylcholine receptors.
PubMed ID: 27344019
DOI: 10.1111/jnc.13718
Sequence Information:
- Length: 468
- Mass: 53054
- Checksum: 7FE91A2E362289C0
- Sequence:
MAARGSGPRA LRLLLLVQLV AGRCGLAGAA GGAQRGLSEP SSIAKHEDSL LKDLFQDYER WVRPVEHLND KIKIKFGLAI SQLVDVDEKN QLMTTNVWLK QEWIDVKLRW NPDDYGGIKV IRVPSDSVWT PDIVLFDNAD GRFEGTSTKT VIRYNGTVTW TPPANYKSSC TIDVTFFPFD LQNCSMKFGS WTYDGSQVDI ILEDQDVDKR DFFDNGEWEI VSATGSKGNR TDSCCWYPYV TYSFVIKRLP LFYTLFLIIP CIGLSFLTVL VFYLPSNEGE KICLCTSVLV SLTVFLLVIE EIIPSSSKVI PLIGEYLVFT MIFVTLSIMV TVFAINIHHR SSSTHNAMAP LVRKIFLHTL PKLLCMRSHV DRYFTQKEET ESGSGPKSSR NTLEAALDSI RYITRHIMKE NDVREVVEDW KFIAQVLDRM FLWTFLFVSI VGSLGLFVPV IYKWANILIP VHIGNANK
Genular Protein ID: 3198071467
Symbol: H0YM98_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
Sequence Information:
- Length: 160
- Mass: 17810
- Checksum: FA1F0090AFCFAA38
- Sequence:
MAARGSGPRA LRLLLLVQLV AGRCGLAGAA GGAQRGLSEP SSIAKHEDSL LKDLFQDYER WVRPVEHLND KIKIKFGLAI SQLVDVDEKN QLMTTNVWLK QEWIDVKLRW NPDDYGGIKV IRVPSDSVWT PDIVLFDNAD GRFEGTSTKT VIRLLKIGNS
Genular Protein ID: 2229739451
Symbol: Q6EWN4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15716100
Title: In vivo RNA-RNA duplexes from human alpha3 and alpha5 nicotinic receptor subunit mRNAs.
PubMed ID: 15716100
Sequence Information:
- Length: 57
- Mass: 6619
- Checksum: 36E995660FD2C213
- Sequence:
DVREVVEDWK FIAQVLDRMF LWTFLFVSIV GSLGLFVPVI YKWANILIPV HIGNANK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.