Details for: CHRNA7

Gene ID: 1139

Symbol: CHRNA7

Ensembl ID: ENSG00000175344

Description: cholinergic receptor nicotinic alpha 7 subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 43.2103
    Cell Significance Index: -10.9600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 6.4308
    Cell Significance Index: 172.3200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.4355
    Cell Significance Index: 1232.2400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.7725
    Cell Significance Index: 79.8800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 2.4068
    Cell Significance Index: 36.2700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.0434
    Cell Significance Index: 44.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.3779
    Cell Significance Index: 262.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 1.3322
    Cell Significance Index: 46.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0120
    Cell Significance Index: 45.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9503
    Cell Significance Index: 12.9700
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.9477
    Cell Significance Index: 9.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8119
    Cell Significance Index: 42.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7486
    Cell Significance Index: 74.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6520
    Cell Significance Index: 588.6700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5883
    Cell Significance Index: 35.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.5441
    Cell Significance Index: 13.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5108
    Cell Significance Index: 55.5600
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: 0.4517
    Cell Significance Index: 4.5200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3434
    Cell Significance Index: 68.8800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2849
    Cell Significance Index: 197.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2560
    Cell Significance Index: 17.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2550
    Cell Significance Index: 5.4300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2122
    Cell Significance Index: 5.9300
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.2028
    Cell Significance Index: 2.6200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1758
    Cell Significance Index: 4.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1559
    Cell Significance Index: 5.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1290
    Cell Significance Index: 7.2400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.0879
    Cell Significance Index: 0.7800
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0690
    Cell Significance Index: 0.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0671
    Cell Significance Index: 12.0900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0577
    Cell Significance Index: 2.5500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0500
    Cell Significance Index: 9.9300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0492
    Cell Significance Index: 1.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0240
    Cell Significance Index: 2.9600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.0150
    Cell Significance Index: 0.9200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0130
    Cell Significance Index: 1.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0112
    Cell Significance Index: 17.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0044
    Cell Significance Index: 1.9600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0024
    Cell Significance Index: 4.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0023
    Cell Significance Index: 0.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0011
    Cell Significance Index: 2.0500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0012
    Cell Significance Index: -0.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0033
    Cell Significance Index: -4.5000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0059
    Cell Significance Index: -2.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0093
    Cell Significance Index: -5.8900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0100
    Cell Significance Index: -0.2000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0136
    Cell Significance Index: -9.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0147
    Cell Significance Index: -10.9200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0155
    Cell Significance Index: -11.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0161
    Cell Significance Index: -2.3400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0186
    Cell Significance Index: -11.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0195
    Cell Significance Index: -10.6700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0200
    Cell Significance Index: -11.2600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0206
    Cell Significance Index: -0.1900
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0208
    Cell Significance Index: -0.4100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0211
    Cell Significance Index: -2.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0315
    Cell Significance Index: -9.0700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0384
    Cell Significance Index: -0.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0481
    Cell Significance Index: -6.6000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0524
    Cell Significance Index: -2.6500
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0542
    Cell Significance Index: -0.7100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0561
    Cell Significance Index: -11.8100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0587
    Cell Significance Index: -6.7300
  • Cell Name: diffuse bipolar 1 cell (CL4033027)
    Fold Change: -0.0593
    Cell Significance Index: -0.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0602
    Cell Significance Index: -4.2600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0607
    Cell Significance Index: -0.9100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0675
    Cell Significance Index: -2.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0679
    Cell Significance Index: -7.9100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0719
    Cell Significance Index: -1.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0734
    Cell Significance Index: -9.4800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0734
    Cell Significance Index: -0.9100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0890
    Cell Significance Index: -4.1500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0930
    Cell Significance Index: -0.6300
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.0940
    Cell Significance Index: -0.5800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0951
    Cell Significance Index: -1.9900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0954
    Cell Significance Index: -9.9300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0965
    Cell Significance Index: -3.0900
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0970
    Cell Significance Index: -1.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0973
    Cell Significance Index: -11.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0994
    Cell Significance Index: -10.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1115
    Cell Significance Index: -7.0300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1127
    Cell Significance Index: -3.6900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.1157
    Cell Significance Index: -1.7300
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.1360
    Cell Significance Index: -1.3700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1361
    Cell Significance Index: -4.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1414
    Cell Significance Index: -3.8500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1428
    Cell Significance Index: -7.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1512
    Cell Significance Index: -11.2700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1551
    Cell Significance Index: -3.8700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1591
    Cell Significance Index: -6.9200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1717
    Cell Significance Index: -5.4300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1778
    Cell Significance Index: -2.0200
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1864
    Cell Significance Index: -2.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1869
    Cell Significance Index: -8.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1933
    Cell Significance Index: -6.7700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1958
    Cell Significance Index: -10.2800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1996
    Cell Significance Index: -3.9800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2052
    Cell Significance Index: -2.5900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2069
    Cell Significance Index: -4.4700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2088
    Cell Significance Index: -4.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pentameric structure:** α7 nAChR is composed of five alpha subunits, which are arranged in a specific configuration to form a functional receptor. 2. **High calcium permeability:** α7 nAChR is highly permeable to calcium ions, which is essential for its role in neurotransmission and synaptic plasticity. 3. **Endogenous ligands:** α7 nAChR can be activated by endogenous ligands, such as nicotine, which can modulate its activity and signaling pathways. 4. **Diverse tissue expression:** α7 nAChR is expressed in multiple cell types, including neurons, glial cells, and non-neuronal cells, which suggests its involvement in various physiological and pathological processes. 5. **Regulation of learning and memory:** α7 nAChR is implicated in learning and memory processes, particularly in the context of synaptic plasticity and neurodegenerative diseases. **Pathways and Functions:** α7 nAChR is involved in various signaling pathways, including: 1. **Acetylcholine-gated channel complex:** α7 nAChR forms a complex with other nicotinic receptors to regulate the flow of ions across the plasma membrane. 2. **Acetylcholine binding and downstream events:** The binding of acetylcholine to α7 nAChR triggers a series of downstream events, including the activation of calcium channels and the regulation of excitatory postsynaptic potential. 3. **Amyloid-beta binding:** α7 nAChR can bind amyloid-beta peptides, which can modulate its activity and signaling pathways. 4. **Calcium channel activity:** α7 nAChR is highly permeable to calcium ions, which is essential for its role in neurotransmission and synaptic plasticity. 5. **Excitatory postsynaptic potential:** α7 nAChR is involved in regulating excitatory postsynaptic potential, particularly in the context of synaptic plasticity and learning. **Clinical Significance:** α7 nAChR is implicated in various neurological and psychiatric disorders, including: 1. **Alzheimer's disease:** α7 nAChR is involved in amyloid-beta formation and clearance, and its dysregulation is associated with Alzheimer's disease. 2. **Nicotine addiction:** α7 nAChR is involved in nicotine addiction, and its dysregulation can contribute to the development of nicotine dependence. 3. **Asthma:** α7 nAChR is expressed in airway smooth muscle cells and is involved in regulating airway constriction and inflammation. 4. **Cancer:** α7 nAChR is involved in regulating cell growth and apoptosis, and its dysregulation can contribute to cancer development. In conclusion, α7 nAChR is a key player in neurotransmission, learning, and memory, and its dysregulation is implicated in various neurological and psychiatric disorders. Further research is needed to fully understand the role of α7 nAChR in these processes and to develop novel therapeutic strategies for the treatment of related diseases.

Genular Protein ID: 987432373

Symbol: ACHA7_HUMAN

Name: Neuronal acetylcholine receptor subunit alpha-7

UniProtKB Accession Codes:

P36544 A8K7Q4 B4DFS0 Q15826 Q8IUZ4 Q96RH2 Q99555 Q9BXH0

Database IDs:

AGR 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 2 BioGRID-ORCS 2 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 2 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 2 DrugBank 45 DrugCentral 1 EMBL 26 EMDB 18 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 50 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 2 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 32 PDBsum 32 PIR 2 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 5 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8145738

Title: Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

PubMed ID: 8145738

PubMed ID: 9782083

Title: Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).

PubMed ID: 9782083

DOI: 10.1006/geno.1998.5363

PubMed ID: 8906617

Title: Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

PubMed ID: 8906617

DOI: 10.1007/bf02736842

PubMed ID: 9009220

Title: Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.

PubMed ID: 9009220

DOI: 10.1016/s0014-5793(96)01383-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8188270

Title: Molecular cloning and chromosomal localization of the human alpha 7-nicotinic receptor subunit gene (CHRNA7).

PubMed ID: 8188270

DOI: 10.1006/geno.1994.1075

PubMed ID: 11829490

Title: A 3-Mb map of a large segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14.

PubMed ID: 11829490

DOI: 10.1006/geno.2002.6694

PubMed ID: 15609996

Title: Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes.

PubMed ID: 15609996

DOI: 10.1021/bi048918g

PubMed ID: 11840567

Title: Cluster analysis of an extensive human breast cancer cell line protein expression map database.

PubMed ID: 11840567

DOI: 10.1002/1615-9861(200202)2:2<212::aid-prot212>3.0.co;2-h

PubMed ID: 15504725

Title: Ric-3 promotes functional expression of the nicotinic acetylcholine receptor alpha7 subunit in mammalian cells.

PubMed ID: 15504725

DOI: 10.1074/jbc.m410039200

PubMed ID: 16120769

Title: RIC-3 enhances functional expression of multiple nicotinic acetylcholine receptor subtypes in mammalian cells.

PubMed ID: 16120769

DOI: 10.1124/mol.105.017459

PubMed ID: 27344019

Title: Functional interaction between Lypd6 and nicotinic acetylcholine receptors.

PubMed ID: 27344019

DOI: 10.1111/jnc.13718

PubMed ID: 27789755

Title: A Genome-Wide Arrayed cDNA Screen to Identify Functional Modulators of alpha7 Nicotinic Acetylcholine Receptors.

PubMed ID: 27789755

DOI: 10.1177/1087057116676086

PubMed ID: 32783947

Title: NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly.

PubMed ID: 32783947

DOI: 10.1016/j.celrep.2020.108025

Sequence Information:

  • Length: 502
  • Mass: 56449
  • Checksum: D94B3A482EAA0E42
  • Sequence:
    • MRCSPGGVWL ALAASLLHVS LQGEFQRKLY KELVKNYNPL ERPVANDSQP LTVYFSLSLL 
QIMDVDEKNQ VLTTNIWLQM SWTDHYLQWN VSEYPGVKTV RFPDGQIWKP DILLYNSADE 
RFDATFHTNV LVNSSGHCQY LPPGIFKSSC YIDVRWFPFD VQHCKLKFGS WSYGGWSLDL 
QMQEADISGY IPNGEWDLVG IPGKRSERFY ECCKEPYPDV TFTVTMRRRT LYYGLNLLIP 
CVLISALALL VFLLPADSGE KISLGITVLL SLTVFMLLVA EIMPATSDSV PLIAQYFAST 
MIIVGLSVVV TVIVLQYHHH DPDGGKMPKW TRVILLNWCA WFLRMKRPGE DKVRPACQHK 
QRRCSLASVE MSAVAPPPAS NGNLLYIGFR GLDGVHCVPT PDSGVVCGRM ACSPTHDEHL 
LHGGQPPEGD PDLAKILEEV RYIANRFRCQ DESEAVCSEW KFAACVVDRL CLMAFSVFTI 
ICTIGILMSA PNFVEAVSKD FA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.