Details for: Asic1

Gene ID: 11419

Symbol: Asic1

Ensembl ID: ENSMUSG00000023017

Description: acid-sensing ion channel 1

Associated with

Other Information

Genular Protein ID: 4258670724

Symbol: ASIC1_MOUSE

Name: Acid-sensing ion channel 1

UniProtKB Accession Codes:

Q6NXK8 Q50K97

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 2 Ensembl 2 GO 30 Gene3D 3 GeneTree 1 Genevisible 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 2 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11988176

Title: The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory.

PubMed ID: 11988176

DOI: 10.1016/s0896-6273(02)00661-x

PubMed ID: 12843249

Title: Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning.

PubMed ID: 12843249

DOI: 10.1523/jneurosci.23-13-05496.2003

PubMed ID: 15369669

Title: Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

PubMed ID: 15369669

DOI: 10.1016/j.cell.2004.08.026

PubMed ID: 15578512

Title: The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

PubMed ID: 15578512

DOI: 10.1053/j.gastro.2004.08.061

PubMed ID: 15471860

Title: Stomatin modulates gating of acid-sensing ion channels.

PubMed ID: 15471860

DOI: 10.1074/jbc.m407708200

PubMed ID: 17060608

Title: Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.

PubMed ID: 17060608

DOI: 10.1073/pnas.0608018103

PubMed ID: 17662962

Title: Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit.

PubMed ID: 17662962

DOI: 10.1016/j.biopsych.2007.05.008

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 526
  • Mass: 59668
  • Checksum: 5462B3FEB5532726
  • Sequence:
    • MELKTEEEEV GGVQPVSIQA FASSSTLHGL AHIFSYERLS LKRALWALCF LGSLAVLLCV 
CTERVQYYFC YHHVTKLDEV AASQLTFPAV TLCNLNEFRF SQVSKNDLYH AGELLALLNN 
RYEIPDTQMA DEKQLEILQD KANFRSFKPK PFNMREFYDR AGHDIRDMLL SCHFRGEACS 
AEDFKVVFTR YGKCYTFNSG QDGRPRLKTM KGGTGNGLEI MLDIQQDEYL PVWGETDETS 
FEAGIKVQIH SQDEPPFIDQ LGFGVAPGFQ TFVSCQEQRL IYLPSPWGTC NAVTMDSDFF 
DSYSITACRI DCETRYLVEN CNCRMVHMPG DAPYCTPEQY KECADPALDF LVEKDQEYCV 
CEMPCNLTRY GKELSMVKIP SKASAKYLAK KFNKSEQYIG ENILVLDIFF EVLNYETIEQ 
KKAYEIAGLL GDIGGQMGLF IGASILTVLE LFDYAYEVIK HRLCRRGKCQ KEAKRNSADK 
GVALSLDDVK RHNPCESLRG HPAGMTYAAN ILPHHPARGT FEDFTC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.