Details for: Ace
Associated with
Other Information
Genular Protein ID: 710966629
Symbol: ACE_MOUSE
Name: Dipeptidyl carboxypeptidase I
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2545691
Title: Mouse angiotensin-converting enzyme is a protein composed of two homologous domains.
PubMed ID: 2545691
PubMed ID: 2164636
Title: Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene.
PubMed ID: 2164636
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2841312
Title: The isolation of angiotensin-converting enzyme cDNA.
PubMed ID: 2841312
PubMed ID: 2835538
Title: Partial protein sequence of mouse and bovine kidney angiotensin converting enzyme.
PubMed ID: 2835538
DOI: 10.1038/ki.1988.48
PubMed ID: 1651914
Title: Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme.
PubMed ID: 1651914
PubMed ID: 7753170
Title: Male-female differences in fertility and blood pressure in ACE-deficient mice.
PubMed ID: 7753170
DOI: 10.1038/375146a0
PubMed ID: 8642790
Title: Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility.
PubMed ID: 8642790
PubMed ID: 9231832
Title: Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.
PubMed ID: 9231832
PubMed ID: 9664078
Title: Selective restoration of male fertility in mice lacking angiotensin-converting enzymes by sperm-specific expression of the testicular isozyme.
PubMed ID: 9664078
DOI: 10.1172/jci3545
PubMed ID: 9482924
Title: Angiotensin-converting enzyme and male fertility.
PubMed ID: 9482924
PubMed ID: 10831599
Title: Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme.
PubMed ID: 10831599
PubMed ID: 11303049
Title: RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis.
PubMed ID: 11303049
PubMed ID: 11723129
Title: The germinal isozyme of angiotensin-converting enzyme can substitute for the somatic isozyme in maintaining normal renal structure and functions.
PubMed ID: 11723129
PubMed ID: 12777443
Title: Maintenance of normal blood pressure and renal functions are independent effects of angiotensin-converting enzyme.
PubMed ID: 12777443
PubMed ID: 14757757
Title: Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice.
PubMed ID: 14757757
PubMed ID: 16154999
Title: Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.
PubMed ID: 16154999
PubMed ID: 15665832
Title: Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization.
PubMed ID: 15665832
DOI: 10.1038/nm1179
PubMed ID: 16270063
Title: Male fertility is dependent on dipeptidase activity of testis ACE.
PubMed ID: 16270063
DOI: 10.1038/nm1105-1140
PubMed ID: 16944957
Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.
PubMed ID: 16944957
DOI: 10.1021/pr060186m
PubMed ID: 17634445
Title: Dipeptidase-inactivated tACE action in vivo: selective inhibition of sperm-zona pellucida binding in the mouse.
PubMed ID: 17634445
PubMed ID: 17135368
Title: Vascular expression of germinal ACE fails to maintain normal blood pressure in ACE-/- mice.
PubMed ID: 17135368
PubMed ID: 17114649
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
PubMed ID: 17114649
PubMed ID: 18443281
Title: Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance.
PubMed ID: 18443281
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23535237
Title: Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling.
PubMed ID: 23535237
PubMed ID: 35201898
Title: Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid.
PubMed ID: 35201898
Sequence Information:
- Length: 1312
- Mass: 150918
- Checksum: 7DF9F5BE91762DFF
- Sequence:
MGAASGQRGR WPLSPPLLML SLLVLLLQPS PAPALDPGLQ PGNFSPDEAG AQLFAESYNS SAEVVMFQST VASWAHDTNI TEENARRQEE AALVSQEFAE VWGKKAKELY ESIWQNFTDS KLRRIIGSIR TLGPANLPLA QRQQYNSLLS NMSRIYSTGK VCFPNKTATC WSLDPELTNI LASSRSYAKL LFAWEGWHDA VGIPLKPLYQ DFTAISNEAY RQDDFSDTGA FWRSWYESPS FEESLEHIYH QLEPLYLNLH AYVRRALHRR YGDKYVNLRG PIPAHLLGDM WAQSWENIYD MVVPFPDKPN LDVTSTMVQK GWNATHMFRV SEEFFTSLGL SPMPPEFWAE SMLEKPTDGR EVVCHASAWD FYNRKDFRIK QCTRVTMEQL ATVHHEMGHV QYYLQYKDLH VSLRRGANPG FHEAIGDVLA LSVSTPAHLH KIGLLDHVTN DIESDINYLL KMALEKIAFL PFGYLVDQWR WGVFSGRTPP SRYNFDWWYL RTKYQGICPP VARNETHFDA GAKFHIPNVT PYIRYFVSFV LQFQFHQALC KEAGHQGPLH QCDIYQSAQA GAKLKQVLQA GCSRPWQEVL KDLVGSDALD AKALLEYFQP VSQWLEEQNQ RNGEVLGWPE NQWRPPLPDN YPEGIDLETD EAKADRFVEE YDRTAQVLLN EYAEANWQYN TNITIEGSKI LLEKSTEVSN HTLKYGTRAK TFDVSNFQNS SIKRIIKKLQ NLDRAVLPPK ELEEYNQILL DMETTYSLSN ICYTNGTCMP LEPDLTNMMA TSRKYEELLW AWKSWRDKVG RAILPFFPKY VEFSNKIAKL NGYTDAGDSW RSLYESDNLE QDLEKLYQEL QPLYLNLHAY VRRSLHRHYG SEYINLDGPI PAHLLGNMWA QTWSNIYDLV APFPSAPNID ATEAMIKQGW TPRRIFKEAD NFFTSLGLLP VPPEFWNKSM LEKPTDGREV VCHPSAWDFY NGKDFRIKQC TSVNMEDLVI AHHEMGHIQY FMQYKDLPVT FREGANPGFH EAIGDIMALS VSTPKHLYSL NLLSTEGSGY EYDINFLMKM ALDKIAFIPF SYLIDQWRWR VFDGSITKEN YNQEWWSLRL KYQGLCPPVP RSQGDFDPGS KFHVPANVPY VRYFVSFIIQ FQFHEALCRA AGHTGPLHKC DIYQSKEAGK LLADAMKLGY SKPWPEAMKL ITGQPNMSAS AMMNYFKPLT EWLVTENRRH GETLGWPEYN WAPNTARAEG STAESNRVNF LGLYLEPQQA RVGQWVLLFL GVALLVATVG LAHRLYNIRN HHSLRRPHRG PQFGSEVELR HS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.