Details for: CHRND

Gene ID: 1144

Symbol: CHRND

Ensembl ID: ENSG00000135902

Description: cholinergic receptor nicotinic delta subunit

Associated with

Other Information

Genular Protein ID: 293335746

Symbol: ACHD_HUMAN

Name: Acetylcholine receptor subunit delta

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2564429

Title: A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671.

PubMed ID: 2564429

DOI: 10.1523/jneurosci.09-03-01082.1989

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15609996

Title: Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes.

PubMed ID: 15609996

DOI: 10.1021/bi048918g

PubMed ID: 16916845

Title: CHRND mutation causes a congenital myasthenic syndrome by impairing co-clustering of the acetylcholine receptor with rapsyn.

PubMed ID: 16916845

DOI: 10.1093/brain/awl188

PubMed ID: 18398509

Title: Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating.

PubMed ID: 18398509

DOI: 10.1172/jci34527

PubMed ID: 27375219

Title: Mutations causing slow-channel myasthenia reveal that a valine ring in the channel pore of muscle AChR is optimized for stabilizing channel gating.

PubMed ID: 27375219

DOI: 10.1002/humu.23043

PubMed ID: 8872460

Title: New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

PubMed ID: 8872460

DOI: 10.1093/hmg/5.9.1217

PubMed ID: 11782989

Title: Novel delta subunit mutation in slow-channel syndrome causes severe weakness by novel mechanisms.

PubMed ID: 11782989

DOI: 10.1002/ana.10077

PubMed ID: 11435464

Title: Acetylcholine receptor delta subunit mutations underlie a fast-channel myasthenic syndrome and arthrogryposis multiplex congenita.

PubMed ID: 11435464

DOI: 10.1172/jci12935

PubMed ID: 12499478

Title: Congenital myasthenic syndrome caused by low-expressor fast-channel AChR delta subunit mutation.

PubMed ID: 12499478

DOI: 10.1212/01.wnl.0000042422.87384.2f

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 18252226

Title: Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders.

PubMed ID: 18252226

DOI: 10.1016/j.ajhg.2007.11.006

Sequence Information:

  • Length: 517
  • Mass: 58895
  • Checksum: 195CEF69358758BD
  • Sequence:
  • MEGPVLTLGL LAALAVCGSW GLNEEERLIR HLFQEKGYNK ELRPVAHKEE SVDVALALTL 
    SNLISLKEVE ETLTTNVWIE HGWTDNRLKW NAEEFGNISV LRLPPDMVWL PEIVLENNND 
    GSFQISYSCN VLVYHYGFVY WLPPAIFRSS CPISVTYFPF DWQNCSLKFS SLKYTAKEIT 
    LSLKQDAKEN RTYPVEWIII DPEGFTENGE WEIVHRPARV NVDPRAPLDS PSRQDITFYL 
    IIRRKPLFYI INILVPCVLI SFMVNLVFYL PADSGEKTSV AISVLLAQSV FLLLISKRLP 
    ATSMAIPLIG KFLLFGMVLV TMVVVICVIV LNIHFRTPST HVLSEGVKKL FLETLPELLH 
    MSRPAEDGPS PGALVRRSSS LGYISKAEEY FLLKSRSDLM FEKQSERHGL ARRLTTARRP 
    PASSEQAQQE LFNELKPAVD GANFIVNHMR DQNNYNEEKD SWNRVARTVD RLCLFVVTPV 
    MVVGTAWIFL QGVYNQPPPQ PFPGDPYSYN VQDKRFI

Genular Protein ID: 4099709599

Symbol: B4E3W4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 323
  • Mass: 35465
  • Checksum: 6573DD93F5FB7D9D
  • Sequence:
  • MLKNLETSVS CASPRTWCGS QRLCWRTTMT APSRSPTPAT CLSTTTASCT GCHLPSSAPP 
    APSLSPISPS TGRTAPSSSG GEKTSVAISV LLAQSVFLLL ISKRLPATSM AIPLIGKFLL 
    FGMVLVTMVV VICVIVLNIH FRTPSTHVLS EGVKKLFLET LPELLHMSRP AEDGPSPGAL 
    VRRSSSLGYI SKAEEYFLLK SRSDLMFEKQ SERHGLARRL TTARRPPASS EQAQQELFNE 
    LKPAVDGANF IVNHMRDQNN YNEEKDSWNR VARTVDRLCL FVVTPVMVVG TAWIFLQGVY 
    NQPPPQPFPG DPYSYNVQDK RFI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.