Genular: Defining Cellular Identity and Function

Details for: Chrnb2

Gene ID: 11444

Symbol: Chrnb2

Ensembl ID: ENSMUSG00000027950

Description: cholinergic receptor nicotinic beta 2 subunit

Associated with

Acetylcholine binding and downstream events
(R-MMU-181431)
Highly calcium permeable nicotinic acetylcholine receptors
(R-MMU-629597)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
(R-MMU-629594)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
(R-MMU-629587)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Postsynaptic nicotinic acetylcholine receptors
(R-MMU-622327)
Presynaptic nicotinic acetylcholine receptors
(R-MMU-622323)
Transmission across chemical synapses
(R-MMU-112315)
Acetylcholine-gated channel complex
(GO:0005892)
Acetylcholine-gated monoatomic cation-selective channel activity
(GO:0022848)
Acetylcholine binding
(GO:0042166)
Acetylcholine receptor activity
(GO:0015464)
Acetylcholine receptor signaling pathway
(GO:0095500)
Action potential
(GO:0001508)
Associative learning
(GO:0008306)
B cell activation
(GO:0042113)
B cell proliferation
(GO:0042100)
Behavioral response to nicotine
(GO:0035095)
Calcium ion transport
(GO:0006816)
Central nervous system neuron axonogenesis
(GO:0021955)
Central nervous system projection neuron axonogenesis
(GO:0021952)
Chemical synaptic transmission
(GO:0007268)
Cognition
(GO:0050890)
Conditioned taste aversion
(GO:0001661)
Dopamine secretion
(GO:0014046)
Establishment of localization in cell
(GO:0051649)
External side of plasma membrane
(GO:0009897)
Extracellular ligand-gated monoatomic ion channel activity
(GO:0005230)
Heterocyclic compound binding
(GO:1901363)
Lateral geniculate nucleus development
(GO:0021771)
Learning
(GO:0007612)
Locomotory behavior
(GO:0007626)
Membrane
(GO:0016020)
Membrane depolarization
(GO:0051899)
Memory
(GO:0007613)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Negative regulation of neuronal action potential
(GO:1904456)
Nervous system process
(GO:0050877)
Neuronal action potential
(GO:0019228)
Optic nerve morphogenesis
(GO:0021631)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of dopamine secretion
(GO:0033603)
Positive regulation of synaptic transmission, dopaminergic
(GO:0032226)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Quaternary ammonium group binding
(GO:0050997)
Regulation of circadian sleep/wake cycle, non-rem sleep
(GO:0045188)
Regulation of circadian sleep/wake cycle, rem sleep
(GO:0042320)
Regulation of dendrite morphogenesis
(GO:0048814)
Regulation of dopamine metabolic process
(GO:0042053)
Regulation of dopamine secretion
(GO:0014059)
Regulation of membrane potential
(GO:0042391)
Regulation of synapse assembly
(GO:0051963)
Regulation of synaptic transmission, dopaminergic
(GO:0032225)
Response to acetylcholine
(GO:1905144)
Response to cocaine
(GO:0042220)
Response to ethanol
(GO:0045471)
Response to hypoxia
(GO:0001666)
Response to nicotine
(GO:0035094)
Sensory perception of pain
(GO:0019233)
Sensory perception of sound
(GO:0007605)
Signal transduction
(GO:0007165)
Smooth muscle contraction
(GO:0006939)
Social behavior
(GO:0035176)
Synaptic transmission, cholinergic
(GO:0007271)
Synaptic transmission involved in micturition
(GO:0060084)
Transmembrane signaling receptor activity
(GO:0004888)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)
Vestibulocochlear nerve development
(GO:0021562)
Visual learning
(GO:0008542)
Visual perception
(GO:0007601)

Other Information

Proteins

Neuronal acetylcholine receptor subunit beta-2

Genular Protein ID: 1682026749

Symbol: ACHB2_MOUSE

Name: Neuronal acetylcholine receptor subunit beta-2

UniProtKB Accession Codes:

Q9ERK7 Q8BGP7

Database IDs:

Citations:

PubMed ID: 11434511

Title: Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence.

PubMed ID: 11434511

DOI: 10.1097/00008571-200106000-00008

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 501
Mass: 57113
Checksum: 7FFAD47BD86B4493
Sequence:

MARCSNSMAL LFSFGLLWLC SGVLGTDTEE RLVEHLLDPS RYNKLIRPAT NGSELVTVQL 
MVSLAQLISV HEREQIMTTN VWLTQEWEDY RLTWKPEDFD NMKKVRLPSK HIWLPDVVLY 
NNADGMYEVS FYSNAVVSYD GSIFWLPPAI YKSACKIEVK HFPFDQQNCT MKFRSWTYDR 
TEIDLVLKSD VASLDDFTPS GEWDIIALPG RRNENPDDST YVDITYDFII RRKPLFYTIN 
LIIPCVLITS LAILVFYLPS DCGEKMTLCI SVLLALTVFL LLISKIVPPT SLDVPLVGKY 
LMFTMVLVTF SIVTSVCVLN VHHRSPTTHT MAPWVKVVFL EKLPTLLFLQ QPRHRCARQR 
LRLRRRQRER EGAGTLFFRE GPAADPCTCF VNPASMQGLA GAFQAEPAAA GLGRSMGPCS 
CGLREAVDGV RFIADHMRSE DDDQSVREDW KYVAMVIDRL FLWIFVFVCV FGTIGMFLQP 
LFQNYTATTF LHSDHSAPSS K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Chrnb2

Associated with

Other Information

Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence. PubMed ID: 11434511

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 11434511

PubMed ID: 16141072

PubMed ID: 19468303

PubMed ID: 15489334