Genular: Defining Cellular Identity and Function

Details for: Actn3

Gene ID: 11474

Symbol: Actn3

Ensembl ID: ENSMUSG00000006457

Description: actinin alpha 3

Associated with

Striated muscle contraction
(R-MMU-390522)
Actin binding
(GO:0003779)
Actin cytoskeleton organization
(GO:0030036)
Actin filament binding
(GO:0051015)
Bone morphogenesis
(GO:0060349)
Brush border
(GO:0005903)
Calcium ion binding
(GO:0005509)
Cell junction
(GO:0030054)
Cell projection
(GO:0042995)
Cortical actin cytoskeleton
(GO:0030864)
Focal adhesion
(GO:0005925)
Focal adhesion assembly
(GO:0048041)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Muscle cell development
(GO:0055001)
Muscle contraction
(GO:0006936)
Negative regulation of calcineurin-nfat signaling cascade
(GO:0070885)
Negative regulation of cold-induced thermogenesis
(GO:0120163)
Negative regulation of glycolytic process
(GO:0045820)
Negative regulation of oxidative phosphorylation
(GO:0090324)
Negative regulation of relaxation of muscle
(GO:1901078)
Osteoblast differentiation
(GO:0001649)
Plasma membrane
(GO:0005886)
Positive regulation of bone mineralization involved in bone maturation
(GO:1900159)
Positive regulation of fast-twitch skeletal muscle fiber contraction
(GO:0031448)
Positive regulation of glucose catabolic process to lactate via pyruvate
(GO:1904025)
Positive regulation of skeletal muscle fiber development
(GO:0048743)
Positive regulation of skeletal muscle tissue growth
(GO:0048633)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Regulation of aerobic respiration
(GO:1903715)
Regulation of muscle system process
(GO:0090257)
Regulation of the force of skeletal muscle contraction
(GO:0014728)
Response to denervation involved in regulation of muscle adaptation
(GO:0014894)
Sarcomere
(GO:0030017)
Skeletal muscle atrophy
(GO:0014732)
Striated muscle thin filament
(GO:0005865)
Transition between fast and slow fiber
(GO:0014883)
Transmembrane transporter binding
(GO:0044325)
Z disc
(GO:0030018)

Other Information

Proteins

Alpha-actinin-3

Genular Protein ID: 3397828552

Symbol: ACTN3_MOUSE

Name: Alpha-actinin-3

UniProtKB Accession Codes:

O88990 Q14DS8

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 900
Mass: 103043
Checksum: 7F795002CB2B7F8B
Sequence:

MMMVMQPEGL GAGEGPFSGG GGGEYMEQEE DWDRDLLLDP AWEKQQRKTF TAWCNSHLRK 
AGTQIENIEE DFRNGLKLML LLEVISGERL PRPDKGKMRF HKIANVNKAL DFIASKGVKL 
VSIGAEEIVD GNLKMTLGMI WTIILRFAIQ DISVEETSAK EGLLLWCQRK TAPYRNVNVQ 
NFHTSWKDGL ALCALIHRHR PDLIDYAKLR KDDPIGNLNT AFEVAEKYLD IPKMLDAEDI 
VNTPKPDEKA IMTYVSCFYH AFAGAEQAET AANRICKVLA VNQENEKLME EYEKLASELL 
EWIRRTVPWL ENRVGEPSMS AMQRKLEDFR DYRRLHKPPR VQEKCQLEIN FNTLQTKLRL 
SHRPAFMPSE GKLVSDIANA WRGLEQVEKG YEDWLLSEIR RLQRLQHLAE KFQQKASLHE 
AWTRGKEEML NQHDYESASL QEVRALLRRH EAFESDLAAH QDRVEHIAAL AQELNELDYH 
EAASVNSRCQ AICDQWDNLG TLTQKRRDAL ERMEKLLETI DQLQLEFARR AAPFNNWLDG 
AIEDLQDVWL VHSVEETQSL LTAHEQFKAT LPEADRERGA ILGIQGEIQK ICQTYGLRPK 
SGNPYITLSS QDINNKWDTV RKLVPSRDQT LQEELARQQV NERLRRQFAA QANAIGPWIQ 
GKVEEVGRLA AGLAGSLEEQ MAGLRQQEQN IINYKSNIDR LEGDHQLLQE SLVFDNKHTV 
YSMEHIRVGW EQLLTSIART INEVENQVLT RDAKGLSQEQ LNEFRASFNH FDRKRNGMME 
PDDFRACLIS MGYDLGEVEF ARIMTMVDPN AAGVVTFQAF IDFMTRETAE TDTAEQVVAS 
FKILAGDKNY ITPEELRREL PAEQAEYCIR RMAPYKGSGA PSGALDYVAF SSALYGESDL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Actn3

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 15489334