Details for: Ada
Associated with
Other Information
Genular Protein ID: 3493331868
Symbol: ADA_MOUSE
Name: Adenosine deaminase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2410423
Title: Identification of functional murine adenosine deaminase cDNA clones by complementation in Escherichia coli.
PubMed ID: 2410423
PubMed ID: 2387582
Title: Structural and functional analysis of the murine adenosine deaminase gene.
PubMed ID: 2387582
PubMed ID: 11471062
Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.
PubMed ID: 11471062
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7670465
Title: Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
PubMed ID: 7670465
DOI: 10.1038/ng0795-279
PubMed ID: 7731963
Title: Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice.
PubMed ID: 7731963
PubMed ID: 8634299
Title: Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase.
PubMed ID: 8634299
DOI: 10.1021/bi9514119
PubMed ID: 8783262
Title: Adenosine deaminase in rodent median eminence: detection by antibody to the mouse enzyme and co-localization with adenosine deaminase-complexing protein (CD26).
PubMed ID: 8783262
PubMed ID: 9272950
Title: Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development.
PubMed ID: 9272950
PubMed ID: 10720488
Title: Function of murine adenosine deaminase in the gastrointestinal tract.
PubMed ID: 10720488
PubMed ID: 10899903
Title: Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.
PubMed ID: 10899903
PubMed ID: 11435465
Title: Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.
PubMed ID: 11435465
DOI: 10.1172/jci10360
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 1925539
Title: Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations.
PubMed ID: 1925539
PubMed ID: 8672487
Title: Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
PubMed ID: 8672487
DOI: 10.1021/bi952920d
PubMed ID: 8942668
Title: Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
PubMed ID: 8942668
DOI: 10.1021/bi961427e
PubMed ID: 9622483
Title: Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
PubMed ID: 9622483
DOI: 10.1021/bi980324o
Sequence Information:
- Length: 352
- Mass: 39992
- Checksum: E53A8A1FABA148CD
- Sequence:
MAQTPAFNKP KVELHVHLDG AIKPETILYF GKKRGIALPA DTVEELRNII GMDKPLSLPG FLAKFDYYMP VIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVDPMPWNQT EGDVTPDDVV DLVNQGLQEG EQAFGIKVRS ILCCMRHQPS WSLEVLELCK KYNQKTVVAM DLAGDETIEG SSLFPGHVEA YEGAVKNGIH RTVHAGEVGS PEVVREAVDI LKTERVGHGY HTIEDEALYN RLLKENMHFE VCPWSSYLTG AWDPKTTHAV VRFKNDKANY SLNTDDPLIF KSTLDTDYQM TKKDMGFTEE EFKRLNINAA KSSFLPEEEK KELLERLYRE YQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.