Genular: Defining Cellular Identity and Function

Details for: Adam19

Gene ID: 11492

Symbol: Adam19

Ensembl ID: ENSMUSG00000011256

Description: ADAM metallopeptidase domain 19

Associated with

Adherens junctions interactions
(R-MMU-418990)
Cell-cell communication
(R-MMU-1500931)
Cell-cell junction organization
(R-MMU-421270)
Cell junction organization
(R-MMU-446728)
Extracellular matrix organization
(R-MMU-1474244)
Invadopodia formation
(R-MMU-8941237)
Regulation of cdh11 expression and function
(R-MMU-9759475)
Regulation of cdh11 function
(R-MMU-9762292)
Regulation of expression and function of type ii classical cadherins
(R-MMU-9764260)
Regulation of homotypic cell-cell adhesion
(R-MMU-9759476)
Amyloid precursor protein catabolic process
(GO:0042987)
Collagen-containing extracellular matrix
(GO:0062023)
External side of plasma membrane
(GO:0009897)
Golgi apparatus
(GO:0005794)
Heart development
(GO:0007507)
Hydrolase activity
(GO:0016787)
Membrane
(GO:0016020)
Membrane protein ectodomain proteolysis
(GO:0006509)
Metal ion binding
(GO:0046872)
Metalloendopeptidase activity
(GO:0004222)
Metalloendopeptidase activity involved in amyloid precursor protein catabolic process
(GO:1902945)
Metallopeptidase activity
(GO:0008237)
Nucleus
(GO:0005634)
Peptidase activity
(GO:0008233)
Positive regulation of cell-cell adhesion mediated by cadherin
(GO:2000049)
Positive regulation of gene expression
(GO:0010628)
Protein binding
(GO:0005515)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Sh3 domain binding
(GO:0017124)

Other Information

Proteins

Disintegrin and metalloproteinase domain-containing protein 19
Q3UH67_MOUSE

Genular Protein ID: 3573800455

Symbol: ADA19_MOUSE

Name: Disintegrin and metalloproteinase domain-containing protein 19

UniProtKB Accession Codes:

O35674

Database IDs:

Citations:

PubMed ID: 9461614

Title: Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.

PubMed ID: 9461614

DOI: 10.1074/jbc.273.7.4180

PubMed ID: 9622634

Title: Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo.

PubMed ID: 9622634

DOI: 10.1016/s0925-4773(98)00043-4

PubMed ID: 7566181

Title: A metalloprotease-disintegrin participating in myoblast fusion.

PubMed ID: 7566181

DOI: 10.1038/377652a0

PubMed ID: 11116142

Title: Roles of Meltrin beta /ADAM19 in the processing of neuregulin.

PubMed ID: 11116142

DOI: 10.1074/jbc.m007913200

Sequence Information:

Length: 920
Mass: 100860
Checksum: 7094FDD4EE547382
Sequence:

MPGRAGVARF CLLALALQLH WPLAACEPGW TTRGSQEGSP PLQHELIIPQ WRTSESPGRG 
KHPLRAELRV MAEGRELILD LEKNEHLFAP AYTETCYTAS GNPQTSTLKS EDHCFYHGTV 
RDVDESSVTL STCRGIRGLI IVRSNLSYII EPVPNSDSQH RIYRSEHLTL PPGNCGFEHS 
GPTSKDWALQ FTHQTKKQPR RMKREDLHSM KYVELYLVAD YAEFQKNRHD QDATKRKLME 
IANYVDKFYR SLNIRIALVG LEVWTHGDKC EVSENPYSTL WSFLSWRRKL LAQKSHDNAQ 
LITGRSFQGT TIGLAPLMAM CSVYQSGGVS MDHSENAIGV ASTVAHEIGH NFGMSHDSAH 
CCSASAADGG CIMAAATGHP FPKVFSWCNR KELDRYLQTG GGMCLSNMPD TRTLYGGRRC 
GNGYLEDGEE CDCGEEEECK NPCCNASNCT LKEGAECAHG SCCHQCKLVA PGTQCREQVR 
QCDLPEFCTG KSPHCPTNYY QMDGTPCEGG QAYCYNGMCL TYQEQCQQLW GPGARPALDL 
CFERVNAAGD TYGNCGKGLN GQYRKCSPRD AKCGKIQCQS TQARPLESNA VSIDTTITLN 
GRRIHCRGTH VYRGPEEEEG EGDMLDPGLV MTGTKCGHNH ICFEGQCRNT SFFETEGCGK 
KCNGHGVCNN NKNCHCFPGW SPPFCNTPGD GGSVDSGPLP PKSVGPVIAG VFSALFVLAV 
LVLLCHCYRQ SHKLGKPSAL PFKLRHQFSC PFRVSQSGGT GHANPTFKLQ TPQGKRKVTN 
TPESLRKPSH PPPRPPPDYL RVESPPAPLP AHLNRAAGSS PEAGARIERK ESARRPPPSR 
PMPPAPNCLL SQDFSRPRPP QKALPANPVP GQRTGPRSGG TSLLQPPTSG PQPPRPPAVP 
VPKLPEYRSQ RVGAIISSKI

Genular Protein ID: 2672217966

Symbol: Q3UH67_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UH67

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 900
Mass: 98732
Checksum: C2B763A864718EEF
Sequence:

MERTHTVPVH TNGGSQEGSP PLQHELIIPQ WRTSESPGRG KHPLRAELRV MAEGRELILD 
LEKNEHLFAP AYTETCYTAS GNPQTSTLKS EDHCFYHGTV RDVDESSVTL STCRGIRGLI 
IVRSNLSYII EPVPNSDSQH RIYRSEHLTL PPGNCGFEHS GPTSKDWALQ FTHQTKKQPR 
RMKREDLHSM KYVELYLVAD YAEFQKNRHD QDATKRKLME IANYVDKFYR SLNIRIALVG 
LEVWTHGDKC EVSENPYSTL WSFLSWRRKL LAQKSHDNAQ LITGRSFQGT TIGLAPLMAM 
CSVYQSGGVS MDHSENAIGV ASTVAHEIGH NFGMSHDSAH CCSASAADGG CIMAAATGHP 
FPKVFSWCNR KELDRYLQTG GGMCLSNMPD TRTLYGGRRC GNGYLEDGEE CDCGEEEECK 
NPCCNASNCT LKEGAECAHG SCCHQCKLVA PGTQCREQVR QCDLPEFCTG KSPHCPTNYY 
QMDGTPCEGG QAYCYNGMCL TYQEQCQQLW GPGARPALDL CFERVNAAGD TYGNCGKGLN 
GQYRKCSPRD AKCGKIQCQS TQARPLESNA VSIDTTITLN GRRIHCRGTH VYRGPEEEEG 
EGDMLDPGLV MTGTKCGHNH ICFEGQCRNT SFFETEGCGK KCNGHGVCNN NKNCHCFPGW 
SPPFCNTPGD GGSVDSGPLP PKSVGPVIAG VFSALFVLAV LVLLCHCYRQ SHKLGKPSAL 
PFKLRHQFSC PFRVSQSGGT GHANPTFKLQ TPQGKRKVTN TPESLRKPSH PPPRPPPDYL 
RVESPPAPLP AHLNRAAGSS PEAGARIERK ESARRPPPSR PMPPAPNCLL SQDFSRPRPP 
QKALPANPVP GQRTGPRSGG TSLLQPPTSG PQPPRPPAVP VPKLPEYRSQ RVGAIISSKI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adam19

Associated with

Other Information

Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells. PubMed ID: 9461614

Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo. PubMed ID: 9622634

A metalloprotease-disintegrin participating in myoblast fusion. PubMed ID: 7566181

Roles of Meltrin beta /ADAM19 in the processing of neuregulin. PubMed ID: 11116142

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073