Details for: ADCY9
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 244.4305
Cell Significance Index: -38.0200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 149.9743
Cell Significance Index: -38.0400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 78.1735
Cell Significance Index: -36.9100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 73.8695
Cell Significance Index: -30.0100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 31.4744
Cell Significance Index: -30.0500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.8365
Cell Significance Index: -38.0200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.4498
Cell Significance Index: -36.0300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 10.7147
Cell Significance Index: -23.4500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.6856
Cell Significance Index: -38.2200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 3.0734
Cell Significance Index: 446.7600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 3.0419
Cell Significance Index: 74.2200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.7856
Cell Significance Index: 123.2200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.7517
Cell Significance Index: 104.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.3144
Cell Significance Index: 59.4900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.2196
Cell Significance Index: 445.2400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.1558
Cell Significance Index: 165.4400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.0599
Cell Significance Index: 138.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.7406
Cell Significance Index: 345.4200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.7234
Cell Significance Index: 49.1800 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.6709
Cell Significance Index: 26.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.2984
Cell Significance Index: 465.7100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.0442
Cell Significance Index: 20.3800 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.0195
Cell Significance Index: 13.6000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.9973
Cell Significance Index: 689.7700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.8624
Cell Significance Index: 24.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6552
Cell Significance Index: 64.8100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6146
Cell Significance Index: 554.9000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.4867
Cell Significance Index: 7.3400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4383
Cell Significance Index: 19.8700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.4342
Cell Significance Index: 26.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3359
Cell Significance Index: 54.6300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3296
Cell Significance Index: 620.5100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.3013
Cell Significance Index: 16.9100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2797
Cell Significance Index: 8.0600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2125
Cell Significance Index: 23.1100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1998
Cell Significance Index: 4.2700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1976
Cell Significance Index: 4.2800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1942
Cell Significance Index: 123.3300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1762
Cell Significance Index: 3.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1384
Cell Significance Index: 3.4600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1377
Cell Significance Index: 211.9800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1052
Cell Significance Index: 142.9800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0978
Cell Significance Index: 180.4100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0924
Cell Significance Index: 17.5900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0900
Cell Significance Index: 40.8300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0534
Cell Significance Index: 1.2800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0521
Cell Significance Index: 3.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0464
Cell Significance Index: 8.3700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0391
Cell Significance Index: 6.6800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0336
Cell Significance Index: 2.1700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0232
Cell Significance Index: 1.6100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0182
Cell Significance Index: 9.9500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0135
Cell Significance Index: 0.2000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0087
Cell Significance Index: 3.8600 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0181
Cell Significance Index: -0.2600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0291
Cell Significance Index: -4.0000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0390
Cell Significance Index: -4.8000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0394
Cell Significance Index: -29.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0423
Cell Significance Index: -32.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0429
Cell Significance Index: -31.4600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0616
Cell Significance Index: -34.7300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0633
Cell Significance Index: -2.9500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0677
Cell Significance Index: -42.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1101
Cell Significance Index: -31.6800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1639
Cell Significance Index: -18.7800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1655
Cell Significance Index: -19.2900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1861
Cell Significance Index: -6.5400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1906
Cell Significance Index: -40.1500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2172
Cell Significance Index: -4.6100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2223
Cell Significance Index: -23.1500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2278
Cell Significance Index: -29.2000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2390
Cell Significance Index: -24.4100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2675
Cell Significance Index: -34.5600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2676
Cell Significance Index: -5.8600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2933
Cell Significance Index: -15.2800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3114
Cell Significance Index: -36.7300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3369
Cell Significance Index: -17.5000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.3477
Cell Significance Index: -5.8600 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.3779
Cell Significance Index: -5.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3957
Cell Significance Index: -24.9400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.4194
Cell Significance Index: -5.2300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4208
Cell Significance Index: -33.3300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4443
Cell Significance Index: -14.1500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4494
Cell Significance Index: -33.4900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4510
Cell Significance Index: -21.2000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4520
Cell Significance Index: -27.7100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4560
Cell Significance Index: -32.2500 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.4883
Cell Significance Index: -5.3200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5098
Cell Significance Index: -16.6900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.5129
Cell Significance Index: -7.5700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.5248
Cell Significance Index: -7.5200 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.5491
Cell Significance Index: -6.9300 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5526
Cell Significance Index: -11.9400 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5588
Cell Significance Index: -11.0500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.5887
Cell Significance Index: -30.9100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.6027
Cell Significance Index: -12.1000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.6055
Cell Significance Index: -7.5100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.6592
Cell Significance Index: -14.0400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6855
Cell Significance Index: -21.9600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.6865
Cell Significance Index: -24.0500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2299000100
Symbol: ADCY9_HUMAN
Name: ATP pyrophosphate-lyase 9
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9628827
Title: Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9).
PubMed ID: 9628827
PubMed ID: 12972952
Title: An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation.
PubMed ID: 12972952
PubMed ID: 15879435
Title: Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways.
PubMed ID: 15879435
DOI: 10.1093/hmg/ddi175
PubMed ID: 10987815
Title: Characterisation of human adenylyl cyclase IX reveals inhibition by Ca(2+)/Calcineurin and differential mRNA plyadenylation.
PubMed ID: 10987815
PubMed ID: 9628581
Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9628581
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1353
- Mass: 150701
- Checksum: 4CBF051EA49B5B7B
- Sequence:
MASPPHQQLL HHHSTEVSCD SSGDSNSVRV KINPKQLSSN SHPKHCKYSI SSSCSSSGDS GGVPRRVGGG GRLRRQKKLP QLFERASSRW WDPKFDSVNL EEACLERCFP QTQRRFRYAL FYIGFACLLW SIYFAVHMRS RLIVMVAPAL CFLLVCVGFF LFTFTKLYAR HYAWTSLALT LLVFALTLAA QFQVLTPVSG RGDSSNLTAT ARPTDTCLSQ VGSFSMCIEV LFLLYTVMHL PLYLSLCLGV AYSVLFETFG YHFRDEACFP SPGAGALHWE LLSRGLLHGC IHAIGVHLFV MSQVRSRSTF LKVGQSIMHG KDLEVEKALK ERMIHSVMPR IIADDLMKQG DEESENSVKR HATSSPKNRK KKSSIQKAPI AFRPFKMQQI EEVSILFADI VGFTKMSANK SAHALVGLLN DLFGRFDRLC EETKCEKIST LGDCYYCVAG CPEPRADHAY CCIEMGLGMI KAIEQFCQEK KEMVNMRVGV HTGTVLCGIL GMRRFKFDVW SNDVNLANLM EQLGVAGKVH ISEATAKYLD DRYEMEDGKV IERLGQSVVA DQLKGLKTYL ISGQRAKESR CSCAEALLSG FEVIDGSQVS SGPRGQGTAS SGNVSDLAQT VKTFDNLKTC PSCGITFAPK SEAGAEGGAP QNGCQDEHKN STKASGGPNP KTQNGLLSPP QEEKLTNSQT SLCEILQEKG RWAGVSLDQS ALLPLRFKNI REKTDAHFVD VIKEDSLMKD YFFKPPINQF SLNFLDQELE RSYRTSYQEE VIKNSPVKTF ASPTFSSLLD VFLSTTVFLT LSTTCFLKYE AATVPPPPAA LAVFSAALLL EVLSLAVSIR MVFFLEDVMA CTKRLLEWIA GWLPRHCIGA ILVSLPALAV YSHVTSEYET NIHFPVFTGS AALIAVVHYC NFCQLSSWMR SSLATVVGAG PLLLLYVSLC PDSSVLTSPL DAVQNFSSER NPCNSSVPRD LRRPASLIGQ EVVLVFFLLL LLVWFLNREF EVSYRLHYHG DVEADLHRTK IQSMRDQADW LLRNIIPYHV AEQLKVSQTY SKNHDSGGVI FASIVNFSEF YEENYEGGKE CYRVLNELIG DFDELLSKPD YSSIEKIKTI GATYMAASGL NTAQAQDGSH PQEHLQILFE FAKEMMRVVD DFNNNMLWFN FKLRVGFNHG PLTAGVIGTT KLLYDIWGDT VNIASRMDTT GVECRIQVSE ESYRVLSKMG YDFDYRGTVN VKGKGQMKTY LYPKCTDHRV IPQHQLSISP DIRVQVDGSI GRSPTDEIAN LVPSVQYVDK TSLGSDSSTQ AKDAHLSPKR PWKEPVKAEE RGRFGKAIEK DDCDETGIEE ANELTKLNVS KSV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.