Details for: Adcyap1

Gene ID: 11516

Symbol: Adcyap1

Ensembl ID: ENSMUSG00000024256

Description: adenylate cyclase activating polypeptide 1

Associated with

  • Class b/2 (secretin family receptors)
    (R-MMU-373080)
  • G alpha (s) signalling events
    (R-MMU-418555)
  • Glucagon-type ligand receptors
    (R-MMU-420092)
  • Gpcr downstream signalling
    (R-MMU-388396)
  • Gpcr ligand binding
    (R-MMU-500792)
  • Signaling by gpcr
    (R-MMU-372790)
  • Signal transduction
    (R-MMU-162582)
  • Activation of adenylate cyclase activity
    (GO:0007190)
  • Adenylate cyclase-activating g protein-coupled receptor signaling pathway
    (GO:0007189)
  • Behavioral fear response
    (GO:0001662)
  • Camp-mediated signaling
    (GO:0019933)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Histamine secretion
    (GO:0001821)
  • Hormone activity
    (GO:0005179)
  • Insulin secretion
    (GO:0030073)
  • Negative regulation of acute inflammatory response to antigenic stimulus
    (GO:0002865)
  • Negative regulation of acute inflammatory response to non-antigenic stimulus
    (GO:0002878)
  • Negative regulation of cell cycle
    (GO:0045786)
  • Negative regulation of glial cell proliferation
    (GO:0060253)
  • Negative regulation of muscle cell apoptotic process
    (GO:0010656)
  • Negative regulation of potassium ion transport
    (GO:0043267)
  • Nervous system development
    (GO:0007399)
  • Neuron projection
    (GO:0043005)
  • Neuron projection development
    (GO:0031175)
  • Neuropeptide hormone activity
    (GO:0005184)
  • Neuropeptide signaling pathway
    (GO:0007218)
  • Ovarian follicle development
    (GO:0001541)
  • Peptide hormone receptor binding
    (GO:0051428)
  • Perikaryon
    (GO:0043204)
  • Pituitary adenylate cyclase-activating polypeptide receptor binding
    (GO:0031858)
  • Pituitary adenylate cyclase activating polypeptide activity
    (GO:0016521)
  • Positive regulation of camp-mediated signaling
    (GO:0043950)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of chemokine (c-c motif) ligand 5 production
    (GO:0071651)
  • Positive regulation of cold-induced thermogenesis
    (GO:0120162)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of growth hormone secretion
    (GO:0060124)
  • Positive regulation of gtpase activity
    (GO:0043547)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of neuron projection development
    (GO:0010976)
  • Positive regulation of protein kinase activity
    (GO:0045860)
  • Positive regulation of somatostatin secretion
    (GO:0090274)
  • Positive regulation of synaptic transmission, glutamatergic
    (GO:0051968)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of g protein-coupled receptor signaling pathway
    (GO:0008277)
  • Regulation of oligodendrocyte progenitor proliferation
    (GO:0070445)
  • Regulation of postsynaptic membrane potential
    (GO:0060078)
  • Regulation of protein localization
    (GO:0032880)
  • Regulation of protein phosphorylation
    (GO:0001932)
  • Signaling receptor binding
    (GO:0005102)
  • Terminal bouton
    (GO:0043195)
  • Vasodilation
    (GO:0042311)

Other Information

Genular Protein ID: 4152584047

Symbol: PACA_MOUSE

Name: Pituitary adenylate cyclase-activating polypeptide

UniProtKB Accession Codes:

O70176

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 48 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 3 SMART 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9573339

Title: Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene.

PubMed ID: 9573339

DOI: 10.1016/s0378-1119(98)00110-3

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23913443

Title: The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human beta-cells and its targeted inactivation impairs glucose tolerance.

PubMed ID: 23913443

DOI: 10.1210/en.2013-1167

Sequence Information:

  • Length: 175
  • Mass: 19381
  • Checksum: D0E2007DB0C6E8C2
  • Sequence:
    • MTMCSGARLA LLVYGIIMHS SVSCSPAAGL SFPGIRPEDE AYDQDGNPLQ DFYDWDPPGV 
GSPASALRDA YALYYPADRR DVAHEILNEA YRKVLDQLSA RKYLQSVVAR GAGENLGGSA 
VDDPAPLTKR HSDGIFTDSY SRYRKQMAVK KYLAAVLGKR YKQRVKNKGR RIAYL

Genular Protein ID: 1240271445

Symbol: Q8BJT8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BJT8

Database IDs:

AGR 1 ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 InterPro 2 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 Pfam 1 RefSeq 3 SAM 1 SMART 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 170
  • Mass: 18764
  • Checksum: C6E8C2C2C8860852
  • Sequence:
    • MTMCSGARLA LLVYGIIMHS SVSCSPAAGL SFPGIRPEDE AYDQDGNPLQ DFYDWDPPGV 
GSPASALRDA YALYYPADRR DVAHEILNEA YRKVLDQLSA RKYLQSVVAR GAGENLGGSA 
VDDPAPLTKR HSDGIFTDSY SRYRKQMAVK KYLAAVLGKR YKQRVKNKGR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.