CKB | ENSG00000166165 | NCBI 1152

Details for: CKB

Gene ID: 1152

Symbol: CKB

Ensembl ID: ENSG00000166165

Description: creatine kinase B

Associated with

Creatine metabolism
(R-HSA-71288)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Rho gtpase cycle
(R-HSA-9012999)
Rnd3 gtpase cycle
(R-HSA-9696264)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Atp binding
(GO:0005524)
Creatine kinase activity
(GO:0004111)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Extracellular space
(GO:0005615)
Futile creatine cycle
(GO:0140651)
Mitochondrion
(GO:0005739)
Phosphocreatine biosynthetic process
(GO:0046314)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Substantia nigra development
(GO:0021762)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Creatine phosphokinase B-type

Genular Protein ID: 124065685

Symbol: KCRB_HUMAN

Name: Creatine phosphokinase B-type

UniProtKB Accession Codes:

P12277 A8K236 B2R5R4 Q2LE07 Q6FG40 Q9UC66

Database IDs:

Citations:

PubMed ID: 3034271

Title: Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number.

PubMed ID: 3034271

DOI: 10.1016/0006-291x(87)91427-6

PubMed ID: 3692484

Title: Structure and expression of the human creatine kinase B gene.

PubMed ID: 3692484

DOI: 10.1016/0888-7543(87)90004-8

PubMed ID: 2883200

Title: Human creatine kinase-B complementary DNA. Nucleotide sequence, gene expression in lung cancer, and chromosomal assignment to two distinct loci.

PubMed ID: 2883200

DOI: 10.1172/jci112969

PubMed ID: 2771648

Title: Complete nucleotide sequence of the human creatine kinase B gene.

PubMed ID: 2771648

DOI: 10.1093/nar/17.15.6385

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2828370

Title: Isolation of a functional human gene for brain creatine kinase.

PubMed ID: 2828370

DOI: 10.1016/s0021-9258(18)69226-9

PubMed ID: 7637327

Title: Protein analysis of human maculae in relation to age-related maculopathy.

PubMed ID: 7637327

PubMed ID: 8186255

Title: Determination of the catalytic site of creatine kinase by site-directed mutagenesis.

PubMed ID: 8186255

DOI: 10.1016/0167-4838(94)90077-9

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 18977227

Title: Structural studies of human brain-type creatine kinase complexed with the ADP-Mg2+-NO3- -creatine transition-state analogue complex.

PubMed ID: 18977227

DOI: 10.1016/j.febslet.2008.10.039

PubMed ID: 18566107

Title: HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3.

PubMed ID: 18566107

DOI: 10.1093/hmg/ddn172

Sequence Information:

Length: 381
Mass: 42644
Checksum: 637AA67A86AE3059
Sequence:

MPFSNSHNAL KLRFPAEDEF PDLSAHNNHM AKVLTPELYA ELRAKSTPSG FTLDDVIQTG 
VDNPGHPYIM TVGCVAGDEE SYEVFKDLFD PIIEDRHGGY KPSDEHKTDL NPDNLQGGDD 
LDPNYVLSSR VRTGRSIRGF CLPPHCSRGE RRAIEKLAVE ALSSLDGDLA GRYYALKSMT 
EAEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKTFLVWVN EEDHLRVISM 
QKGGNMKEVF TRFCTGLTQI ETLFKSKDYE FMWNPHLGYI LTCPSNLGTG LRAGVHIKLP 
NLGKHEKFSE VLKRLRLQKR GTGGVDTAAV GGVFDVSNAD RLGFSEVELV QMVVDGVKLL 
IEMEQRLEQG QAIDDLMPAQ K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CKB

Associated with

Other Information

Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number. PubMed ID: 3034271

Structure and expression of the human creatine kinase B gene. PubMed ID: 3692484

Human creatine kinase-B complementary DNA. Nucleotide sequence, gene expression in lung cancer, and chromosomal assignment to two distinct loci. PubMed ID: 2883200

Complete nucleotide sequence of the human creatine kinase B gene. PubMed ID: 2771648

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Isolation of a functional human gene for brain creatine kinase. PubMed ID: 2828370

Protein analysis of human maculae in relation to age-related maculopathy. PubMed ID: 7637327

Determination of the catalytic site of creatine kinase by site-directed mutagenesis. PubMed ID: 8186255

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Resveratrol-induced changes of the human adipocyte secretion profile. PubMed ID: 22905912

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Structural studies of human brain-type creatine kinase complexed with the ADP-Mg2+-NO3- -creatine transition-state analogue complex. PubMed ID: 18977227

HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3. PubMed ID: 18566107