Genular: Defining Cellular Identity and Function

Details for: Adh1

Gene ID: 11522

Symbol: Adh1

Ensembl ID: ENSMUSG00000074207

Description: alcohol dehydrogenase 1 (class I)

Associated with

Abacavir adme
(R-MMU-2161522)
Abacavir metabolism
(R-MMU-2161541)
Biological oxidations
(R-MMU-211859)
Drug adme
(R-MMU-9748784)
Metabolism
(R-MMU-1430728)
Phase i - functionalization of compounds
(R-MMU-211945)
Ra biosynthesis pathway
(R-MMU-5365859)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by retinoic acid
(R-MMU-5362517)
Signal transduction
(R-MMU-162582)
Acetaldehyde biosynthetic process
(GO:0046186)
Alcohol dehydrogenase (nad+) activity
(GO:0004022)
Alcohol dehydrogenase activity, zinc-dependent
(GO:0004024)
Behavioral response to ethanol
(GO:0048149)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Ethanol binding
(GO:0035276)
Ethanol catabolic process
(GO:0006068)
Ethanol oxidation
(GO:0006069)
Identical protein binding
(GO:0042802)
Intracellular anatomical structure
(GO:0005622)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Nad-retinol dehydrogenase activity
(GO:0004745)
Nad binding
(GO:0051287)
Nucleoplasm
(GO:0005654)
Organic cyclic compound binding
(GO:0097159)
Oxidoreductase activity
(GO:0016491)
Plasma membrane
(GO:0005886)
Response to retinoic acid
(GO:0032526)
Response to steroid hormone
(GO:0048545)
Response to testosterone
(GO:0033574)
Retinoic acid metabolic process
(GO:0042573)
Retinoid metabolic process
(GO:0001523)
Retinol metabolic process
(GO:0042572)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Alcohol dehydrogenase 1

Genular Protein ID: 3386220579

Symbol: ADH1_MOUSE

Name: Alcohol dehydrogenase 1

UniProtKB Accession Codes:

P00329

Database IDs:

Citations:

PubMed ID: 3157987

Title: Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.

PubMed ID: 3157987

DOI: 10.1073/pnas.82.8.2262

PubMed ID: 2893758

Title: Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3.

PubMed ID: 2893758

DOI: 10.1016/0378-1119(87)90325-8

PubMed ID: 3428612

Title: Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity.

PubMed ID: 3428612

DOI: 10.1016/0378-1119(87)90173-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7937138

Title: Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.

PubMed ID: 7937138

DOI: 10.1093/nar/22.20.4132

PubMed ID: 3011597

Title: Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis.

PubMed ID: 3011597

DOI: 10.1016/0378-1119(86)90101-0

PubMed ID: 7738026

Title: Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family.

PubMed ID: 7738026

DOI: 10.1074/jbc.270.18.10868

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 375
Mass: 39771
Checksum: 7B8AF94C95D35108
Sequence:

MSTAGKVIKC KAAVLWELHK PFTIEDIEVA PPKAHEVRIK MVATGVCRSD DHVVSGTLVT 
PLPAVLGHEG AGIVESVGEG VTCVKPGDKV IPLFSPQCGE CRICKHPESN FCSRSDLLMP 
RGTLREGTSR FSCKGKQIHN FISTSTFSQY TVVDDIAVAK IDGASPLDKV CLIGCGFSTG 
YGSAVKVAKV TPGSTCAVFG LGGVGLSVII GCKAAGAARI IAVDINKDKF AKAKELGATE 
CINPQDYSKP IQEVLQEMTD GGVDFSFEVI GRLDTMTSAL LSCHAACGVS VVVGVPPNAQ 
NLSMNPMLLL LGRTWKGAIF GGFKSKDSVP KLVADFMAKK FPLDPLITHV LPFEKINEAF 
DLLRSGKSIR TVLTF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adh1

Associated with

Other Information

Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase. PubMed ID: 3157987

Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3. PubMed ID: 2893758

Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity. PubMed ID: 3428612

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor. PubMed ID: 7937138

Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis. PubMed ID: 3011597

Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family. PubMed ID: 7738026

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337