Genular: Defining Cellular Identity and Function

Details for: Adh5

Gene ID: 11532

Symbol: Adh5

Ensembl ID: ENSMUSG00000028138

Description: alcohol dehydrogenase 5 (class III), chi polypeptide

Associated with

Biological oxidations
(R-MMU-211859)
Metabolism
(R-MMU-1430728)
Phase i - functionalization of compounds
(R-MMU-211945)
Alcohol dehydrogenase (nad+) activity
(GO:0004022)
Alcohol dehydrogenase activity, zinc-dependent
(GO:0004024)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Ethanol catabolic process
(GO:0006068)
Ethanol oxidation
(GO:0006069)
Fatty acid binding
(GO:0005504)
Fatty acid omega-oxidation
(GO:0010430)
Formaldehyde catabolic process
(GO:0046294)
Formaldehyde dehydrogenase activity
(GO:0018467)
Identical protein binding
(GO:0042802)
Lipid metabolic process
(GO:0006629)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Oxidoreductase activity
(GO:0016491)
Peptidyl-cysteine s-nitrosylation
(GO:0018119)
Positive regulation of blood pressure
(GO:0045777)
Respiratory system process
(GO:0003016)
Response to lipopolysaccharide
(GO:0032496)
Response to nitrosative stress
(GO:0051409)
Response to redox state
(GO:0051775)
Retinoid metabolic process
(GO:0001523)
S-(hydroxymethyl)glutathione dehydrogenase activity
(GO:0051903)
S-(hydroxymethyl)glutathione dehydrogenase nad activity
(GO:0106322)
S-(hydroxymethyl)glutathione dehydrogenase nadp activity
(GO:0106321)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Alcohol dehydrogenase 2

Genular Protein ID: 1341782347

Symbol: ADHX_MOUSE

Name: Alcohol dehydrogenase 2

UniProtKB Accession Codes:

P28474 Q3TW83 Q8C662

Database IDs:

Citations:

PubMed ID: 2053480

Title: Alcohol dehydrogenase gene expression and cloning of the mouse chi-like ADH.

PubMed ID: 2053480

DOI: 10.1007/978-1-4684-5901-2_27

PubMed ID: 1472709

Title: Molecular cloning of mouse alcohol dehydrogenase-B2 cDNA: nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions.

PubMed ID: 1472709

DOI: 10.3109/10425179209034012

PubMed ID: 8647091

Title: Characterization of the functional gene encoding mouse class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) and an unexpressed processed pseudogene with an intact open reading frame.

PubMed ID: 8647091

DOI: 10.1111/j.1432-1033.1996.0496k.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7738026

Title: Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family.

PubMed ID: 7738026

DOI: 10.1074/jbc.270.18.10868

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 374
Mass: 39548
Checksum: 32A3727B5DAB0919
Sequence:

MANQVIRCKA AVAWEAGKPL SIEEIEVAPP KAHEVRIKIL ATAVCHTDAY TLSGADPEGC 
FPVILGHEGA GIVESVGEGV TKLKAGDTVI PLYIPQCGEC KFCLNPKTNL CQKIRVTQGK 
GLMPDGTSRF TCKGKSVFHF MGTSTFSEYT VVADISVAKI DPSAPLDKVC LLGCGISTGY 
GAAVNTAKVE PGSTCAVFGL GGVGLAVIMG CKVAGASRII GIDINKDKFA KAKEFGASEC 
ISPQDFSKSI QEVLVEMTDG GVDYSFECIG NVKVMRSALE AAHKGWGVSV VVGVAASGEE 
ISTRPFQLVT GRTWKGTAFG GWKSVESVPK LVSEYMSKKI KVDEFVTGNL SFDQINQAFD 
LMHSGDSIRT VLKM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adh5

Associated with

Other Information

Alcohol dehydrogenase gene expression and cloning of the mouse chi-like ADH. PubMed ID: 2053480

Molecular cloning of mouse alcohol dehydrogenase-B2 cDNA: nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions. PubMed ID: 1472709

Characterization of the functional gene encoding mouse class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) and an unexpressed processed pseudogene with an intact open reading frame. PubMed ID: 8647091

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family. PubMed ID: 7738026

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337