CISH | ENSG00000114737 | NCBI 1154

Details for: CISH

Gene ID: 1154

Symbol: CISH

Ensembl ID: ENSG00000114737

Description: cytokine inducible SH2 containing protein

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Growth hormone receptor signaling
(R-HSA-982772)
Immune system
(R-HSA-168256)
Interleukin-7 signaling
(R-HSA-1266695)
Metabolism of proteins
(R-HSA-392499)
Neddylation
(R-HSA-8951664)
Post-translational protein modification
(R-HSA-597592)
Signaling by interleukins
(R-HSA-449147)
1-phosphatidylinositol-3-kinase regulator activity
(GO:0046935)
Cellular_component
(GO:0005575)
Cytosol
(GO:0005829)
Intracellular signal transduction
(GO:0035556)
Molecular_function
(GO:0003674)
Negative regulation of signal transduction
(GO:0009968)
Phosphatidylinositol 3-kinase complex
(GO:0005942)
Phosphatidylinositol phosphate biosynthetic process
(GO:0046854)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Protein ubiquitination
(GO:0016567)
Regulation of cell growth
(GO:0001558)

Other Information

Proteins

Cytokine-inducible SH2-containing protein

Genular Protein ID: 959203541

Symbol: CISH_HUMAN

Name: Cytokine-inducible SH2-containing protein

UniProtKB Accession Codes:

Q9NSE2 B2R9N1 G5E9R1 Q9NS38 Q9Y5R1

Database IDs:

Citations:

PubMed ID: 9465889

Title: Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues.

PubMed ID: 9465889

DOI: 10.1159/000134658

PubMed ID: 10902923

Title: Cloning and characterization of CIS 1b (cytokine inducible SH2-containing protein 1b), an alternative splicing form of CIS 1 gene.

PubMed ID: 10902923

DOI: 10.3109/10425170009033983

PubMed ID: 11032736

Title: cDNA representational difference analysis of human neutrophils stimulated by GM-CSF.

PubMed ID: 11032736

DOI: 10.1006/bbrc.2000.3678

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9774439

Title: Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated CIS protein.

PubMed ID: 9774439

DOI: 10.1074/jbc.273.43.28185

PubMed ID: 20484391

Title: CISH and susceptibility to infectious diseases.

PubMed ID: 20484391

DOI: 10.1056/nejmoa0905606

Sequence Information:

Length: 258
Mass: 28663
Checksum: 0BA97804E3B0F608
Sequence:

MVLCVQGPRP LLAVERTGQR PLWAPSLELP KPVMQPLPAG AFLEEVAEGT PAQTESEPKV 
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 
KTTRGPTNVR IEYADSSFRL DSNCLSRPRI LAFPDVVSLV QHYVASCTAD TRSDSPDPAP 
TPALPMPKED APSDPALPAP PPATAVHLKL VQPFVRRSSA RSLQHLCRLV INRLVADVDC 
LPLPRRMADY LRQYPFQL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CISH

Associated with

Other Information

Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. PubMed ID: 9465889

Cloning and characterization of CIS 1b (cytokine inducible SH2-containing protein 1b), an alternative splicing form of CIS 1 gene. PubMed ID: 10902923

cDNA representational difference analysis of human neutrophils stimulated by GM-CSF. PubMed ID: 11032736

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated CIS protein. PubMed ID: 9774439

CISH and susceptibility to infectious diseases. PubMed ID: 20484391