Genular: Defining Cellular Identity and Function

Details for: Adra2b

Gene ID: 11552

Symbol: Adra2b

Ensembl ID: ENSMUSG00000058620

Description: adrenergic receptor, alpha 2b

Associated with

Adrenaline signalling through alpha-2 adrenergic receptor
(R-MMU-392023)
Adrenoceptors
(R-MMU-390696)
Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
G alpha (z) signalling events
(R-MMU-418597)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet aggregation (plug formation)
(R-MMU-76009)
Signaling by gpcr
(R-MMU-372790)
Activation of protein kinase b activity
(GO:0032148)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adrenergic receptor activity
(GO:0004935)
Adrenergic receptor signaling pathway
(GO:0071875)
Alpha2-adrenergic receptor activity
(GO:0004938)
Angiogenesis
(GO:0001525)
Cell surface
(GO:0009986)
Cytosol
(GO:0005829)
Epinephrine binding
(GO:0051379)
Female pregnancy
(GO:0007565)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular membrane-bounded organelle
(GO:0043231)
Mapk cascade
(GO:0000165)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of uterine smooth muscle contraction
(GO:0070474)
Protein binding
(GO:0005515)
Receptor transactivation
(GO:0035624)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of vascular associated smooth muscle contraction
(GO:0003056)
Regulation of vasoconstriction
(GO:0019229)
Signal transduction
(GO:0007165)

Other Information

Proteins

Alpha-2B adrenergic receptor
Q925K6_MOUSE

Genular Protein ID: 2390766182

Symbol: ADA2B_MOUSE

Name: Alpha-2B adrenergic receptor

UniProtKB Accession Codes:

P30545 F8VQ23

Database IDs:

Citations:

PubMed ID: 1336396

Title: Molecular cloning and characterization of a mouse alpha 2C2 adrenoceptor subtype gene.

PubMed ID: 1336396

DOI: 10.1016/0167-4781(92)90126-k

PubMed ID: 1354956

Title: Cloning and expression of the mouse homolog of the human alpha 2-C2 adrenergic receptor.

PubMed ID: 1354956

DOI: 10.1016/s0006-291x(05)81544-x

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 453
Mass: 50443
Checksum: BB3FFA3D7B1D4B0F
Sequence:

MSGPAMVHQE PYSVQATAAI ASAITFLILF TIFGNALVIL AVLTSRSLRA PQNLFLVSLA 
AADILVATLI IPFSLANELL GYWYFWRAWC EVYLALDVLF CTSSIVHLCA ISLDRYWAVS 
RALEYNSKRT PRRIKCIILT VWLIAAVISL PPLIYKGDQR PEPHGLPQCE LNQEAWYILA 
SSIGSFFAPC LIMILVYLRI YVIAKRSHCR GLGAKRGSGE GESKKPHPAA GGVPASAKVP 
TLVSPLSSVG EANGHPKPPR EKEEGETPED PEARALPPNW SALPRSVQDQ KKGTSGATAE 
KGAEEDEEEV EECEPQTLPA SPASVFNPPL QQPQTSRVLA TLRGQVLLSK NVGVASGQWW 
RRRTQLSREK RFTFVLAVVI GVFVVCWFPF FFSYSLGAIC PQHCKVPHGL FQFFFWIGYC 
NSSLNPVIYT IFNQDFRRAF RRILCRQWTQ TGW

Genular Protein ID: 4196162278

Symbol: Q925K6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q925K6

Database IDs:

Citations:

PubMed ID: 11471062

Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.

PubMed ID: 11471062

DOI: 10.1007/s00335-001-1001-x

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 448
Mass: 49999
Checksum: B37E5E21B0EC4625
Sequence:

MVHQEPYSVQ ATAAIASAIT FLILFTIFGN ALVILAVLTS RSLRAPQNLF LVSLAAADIL 
VATLIIPFSL ANELLGYWYF WRAWCEVYLA LDVLFCTSSI VHLCAISLDR YWAVSRALEY 
NSKRTPRRIK CIILTVWLIA AVISLPPLIY KGDQRPEPHG LPQCELNQEA WYILASSIGS 
FFAPCLIMIL VYLRIYVIAK RSHCRGLGAK RGSGEGESKK PHPAAGGVPA SAKVPTLVSP 
LSSVGEANGH PKPPREKEEG ETPEDPEARA LPPNWSALPR SVQDQKKGTS GATAEKGAEE 
DEEEVEECEP QTLPASPASV FNPPLQQPQT SRVLATLRGQ VLLSKNVGVA SGQWWRRRTQ 
LSREKRFTFV LAVVIGVFVV CWFPFFFSYS LGAICPQHCK VPHGLFQFFF WIGYCNSSLN 
PVIYTIFNQD FRRAFRRILC RQWTQTGW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adra2b

Associated with

Other Information

Molecular cloning and characterization of a mouse alpha 2C2 adrenoceptor subtype gene. PubMed ID: 1336396

Cloning and expression of the mouse homolog of the human alpha 2-C2 adrenergic receptor. PubMed ID: 1354956

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

High-throughput sequence identification of gene coding variants within alcohol-related QTLs. PubMed ID: 11471062

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Database document:

PubMed ID: 1336396

PubMed ID: 1354956

PubMed ID: 19468303

PubMed ID: 11471062

PubMed ID: 19468303