Genular: Defining Cellular Identity and Function

Details for: Adra2c

Gene ID: 11553

Symbol: Adra2c

Ensembl ID: ENSMUSG00000045318

Description: adrenergic receptor, alpha 2c

Associated with

Adrenaline,noradrenaline inhibits insulin secretion
(R-MMU-400042)
Adrenaline signalling through alpha-2 adrenergic receptor
(R-MMU-392023)
Adrenoceptors
(R-MMU-390696)
Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
G alpha (z) signalling events
(R-MMU-418597)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hemostasis
(R-MMU-109582)
Integration of energy metabolism
(R-MMU-163685)
Metabolism
(R-MMU-1430728)
Metabolism of proteins
(R-MMU-392499)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet aggregation (plug formation)
(R-MMU-76009)
Regulation of insulin secretion
(R-MMU-422356)
Signaling by gpcr
(R-MMU-372790)
Surfactant metabolism
(R-MMU-5683826)
Activation of protein kinase b activity
(GO:0032148)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adrenergic receptor activity
(GO:0004935)
Adrenergic receptor signaling pathway
(GO:0071875)
Alpha-2a adrenergic receptor binding
(GO:0031694)
Alpha2-adrenergic receptor activity
(GO:0004938)
Axon
(GO:0030424)
Axon terminus
(GO:0043679)
Cytoplasm
(GO:0005737)
Epinephrine binding
(GO:0051379)
Female pregnancy
(GO:0007565)
Glutamatergic synapse
(GO:0098978)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Membrane
(GO:0016020)
Negative regulation of uterine smooth muscle contraction
(GO:0070473)
Neuronal cell body
(GO:0043025)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of vasoconstriction
(GO:0045907)
Postsynaptic density membrane
(GO:0098839)
Postsynaptic membrane
(GO:0045211)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Receptor transactivation
(GO:0035624)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of vasoconstriction
(GO:0019229)
Signal transduction
(GO:0007165)

Other Information

Proteins

Alpha-2C adrenergic receptor

Genular Protein ID: 2388977744

Symbol: ADA2C_MOUSE

Name: Alpha-2C adrenergic receptor

UniProtKB Accession Codes:

Q01337

Database IDs:

Citations:

PubMed ID: 1353249

Title: Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding.

PubMed ID: 1353249

PubMed ID: 8387367

Title: Molecular characterization of a murine homologue of alpha 2C4 adrenoceptor subtype gene.

PubMed ID: 8387367

Sequence Information:

Length: 458
Mass: 49906
Checksum: C0A8BDF0302BF1FB
Sequence:

MASPALAAAL AAAAAEGPNG SDAGEWGSGG GANASGTDWV PPPGQYSAGA VAGLAAVVGF 
LIVFTVVGNV LVVIAVLTSR ALRAPQNLFL VSLASADILV ATLVMPFSLA NELMAYWYFG 
QVWCGVYLAL DVLFCTSSIV HLCAISLDRY WSVTQAVEYN LKRTPRRVKA TIVAVWLISA 
VISFPPLVSF YRRPDGAAYP QCGLNDETWY ILSSCIGSFF APCLIMGLVY ARIYRVAKLR 
TRTLSEKRGP AGPDGASPTT ENGLGKAAGE NGHCAPPRTE VEPDESSAAE RRRRRGALRR 
GGRRREGAEG DTGSADGPGP GLAAEQGART ASRSPGPGGR LSRASSRSVE FFLSRRRRAR 
SSVCRRKVAQ AREKRFTFVL AVVMGVFVLC WFPFFFSYSL YGICREACQL PEPLFKFFFW 
IGYCNSSLNP VIYTVFNQDF RRSFKHILFR RRRRGFRQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.