Genular: Defining Cellular Identity and Function

Details for: Adrb2

Gene ID: 11555

Symbol: Adrb2

Ensembl ID: ENSMUSG00000045730

Description: adrenergic receptor, beta 2

Associated with

Adrenoceptors
(R-MMU-390696)
Amine ligand-binding receptors
(R-MMU-375280)
Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Deubiquitination
(R-MMU-5688426)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Signaling by gpcr
(R-MMU-372790)
Ub-specific processing proteases
(R-MMU-5689880)
Vesicle-mediated transport
(R-MMU-5653656)
Activation of adenylate cyclase activity
(GO:0007190)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase binding
(GO:0008179)
Adrenergic receptor activity
(GO:0004935)
Adrenergic receptor signaling pathway
(GO:0071875)
Amyloid-beta binding
(GO:0001540)
Associative learning
(GO:0008306)
B2 bradykinin receptor binding
(GO:0031713)
Beta2-adrenergic receptor activity
(GO:0004941)
Blood vessel diameter maintenance
(GO:0097746)
Bone resorption
(GO:0045453)
Brown fat cell differentiation
(GO:0050873)
Caveola
(GO:0005901)
Cellular response to amyloid-beta
(GO:1904646)
Cellular response to hypoxia
(GO:0071456)
Desensitization of g protein-coupled receptor signaling pathway by arrestin
(GO:0002032)
Diaphragm contraction
(GO:0002086)
Diet induced thermogenesis
(GO:0002024)
Endosome
(GO:0005768)
Enzyme binding
(GO:0019899)
Excitatory postsynaptic potential
(GO:0060079)
G-protein alpha-subunit binding
(GO:0001965)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Heat generation
(GO:0031649)
Identical protein binding
(GO:0042802)
Ionotropic glutamate receptor binding
(GO:0035255)
Membrane
(GO:0016020)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of multicellular organism growth
(GO:0040015)
Negative regulation of ossification
(GO:0030279)
Negative regulation of smooth muscle contraction
(GO:0045986)
Negative regulation of urine volume
(GO:0035811)
Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
(GO:0002025)
Norepinephrine binding
(GO:0051380)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of ampa receptor activity
(GO:2000969)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of autophagosome maturation
(GO:1901098)
Positive regulation of bone mineralization
(GO:0030501)
Positive regulation of calcium ion import across plasma membrane
(GO:1905665)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of lipophagy
(GO:1904504)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of mini excitatory postsynaptic potential
(GO:0061885)
Positive regulation of potassium ion transport
(GO:0043268)
Positive regulation of protein kinase a signaling
(GO:0010739)
Positive regulation of protein serine/threonine kinase activity
(GO:0071902)
Positive regulation of skeletal muscle tissue growth
(GO:0048633)
Positive regulation of sodium ion transport
(GO:0010765)
Positive regulation of the force of heart contraction by epinephrine
(GO:0003059)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Potassium channel regulator activity
(GO:0015459)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein phosphatase 2a binding
(GO:0051721)
Receptor-mediated endocytosis
(GO:0006898)
Receptor-receptor interaction
(GO:0090722)
Regulation of calcium ion transport
(GO:0051924)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of sodium ion transport
(GO:0002028)
Regulation of systemic arterial blood pressure by norepinephrine-epinephrine
(GO:0001993)
Response to catecholamine
(GO:0071869)
Response to cold
(GO:0009409)
Signal transduction
(GO:0007165)
Smooth muscle contraction
(GO:0006939)
Synaptic transmission, glutamatergic
(GO:0035249)
Transcription by rna polymerase ii
(GO:0006366)
Vasodilation
(GO:0042311)

Other Information

Proteins

Beta-2 adrenergic receptor

Genular Protein ID: 230028581

Symbol: ADRB2_MOUSE

Name: Beta-2 adrenergic receptor

UniProtKB Accession Codes:

P18762 Q8BH38

Database IDs:

Citations:

PubMed ID: 2834198

Title: Isoproterenol response following transfection of the mouse beta 2-adrenergic receptor gene into Y1 cells.

PubMed ID: 2834198

DOI: 10.1002/j.1460-2075.1988.tb02792.x

PubMed ID: 2549959

Title: Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts.

PubMed ID: 2549959

DOI: 10.1042/bj2600053

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 418
Mass: 46998
Checksum: 51D1EC73D7619D58
Sequence:

MGPHGNDSDF LLAPNGSRAP DHDVTQERDE AWVVGMAILM SVIVLAIVFG NVLVITAIAK 
FERLQTVTNY FIISLACADL VMGLAVVPFG ASHILMKMWN FGNFWCEFWT SIDVLCVTAS 
IETLCVIAVD RYVAITSPFK YQSLLTKNKA RVVILMVWIV SGLTSFLPIQ MHWYRATHKK 
AIDCYTEETC CDFFTNQAYA IASSIVSFYV PLVVMVFVYS RVFQVAKRQL QKIDKSEGRF 
HAQNLSQVEQ DGRSGHGLRR SSKFCLKEHK ALKTLGIIMG TFTLCWLPFF IVNIVHVIRD 
NLIPKEVYIL LNWLGYVNSA FNPLIYCRSP DFRIAFQELL CLRRSSSKTY GNGYSSNSNG 
RTDYTGEPNT CQLGQEREQE LLCEDPPGME GFVNCQGTVP SLSVDSQGRN CSTNDSPL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adrb2

Associated with

Other Information

Isoproterenol response following transfection of the mouse beta 2-adrenergic receptor gene into Y1 cells. PubMed ID: 2834198

Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts. PubMed ID: 2549959

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 2834198

PubMed ID: 2549959

PubMed ID: 16141072

PubMed ID: 15489334