Genular: Defining Cellular Identity and Function

Details for: Adss1

Gene ID: 11565

Symbol: Adss1

Ensembl ID: ENSMUSG00000011148

Description: adenylosuccinate synthase 1

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Nucleotide biosynthesis
(R-MMU-8956320)
Purine ribonucleoside monophosphate biosynthesis
(R-MMU-73817)
'de novo' amp biosynthetic process
(GO:0044208)
Actin filament binding
(GO:0051015)
Adenylosuccinate synthase activity
(GO:0004019)
Amp biosynthetic process
(GO:0006167)
Amp salvage
(GO:0044209)
Aspartate metabolic process
(GO:0006531)
Cytoplasm
(GO:0005737)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Identical protein binding
(GO:0042802)
Imp metabolic process
(GO:0046040)
Ligase activity
(GO:0016874)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Nucleotide binding
(GO:0000166)
Protein binding
(GO:0005515)
Purine nucleotide biosynthetic process
(GO:0006164)
Purine nucleotide metabolic process
(GO:0006163)

Other Information

Proteins

PURA1_MOUSE

Genular Protein ID: 3643839896

Symbol: PURA1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P28650 Q8CHQ1

Database IDs:

Citations:

PubMed ID: 1939273

Title: Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase.

PubMed ID: 1939273

DOI: 10.1016/s0021-9258(18)54611-1

PubMed ID: 8308018

Title: Amplification of an adenylosuccinate synthetase gene in alanosine-resistant murine T-lymphoma cells. Molecular cloning of a cDNA encoding the 'non-muscle' isozyme.

PubMed ID: 8308018

DOI: 10.1016/s0021-9258(17)41805-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12482871

Title: Variations in the response of mouse isozymes of adenylosuccinate synthetase to inhibitors of physiological relevance.

PubMed ID: 12482871

DOI: 10.1074/jbc.m210838200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 11560929

Title: Recombinant mouse muscle adenylosuccinate synthetase: overexpression, kinetics, and crystal structure.

PubMed ID: 11560929

DOI: 10.1074/jbc.m106294200

PubMed ID: 12004071

Title: IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase.

PubMed ID: 12004071

DOI: 10.1074/jbc.m203730200

PubMed ID: 12186864

Title: Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.

PubMed ID: 12186864

DOI: 10.1074/jbc.m204952200

PubMed ID: 16981730

Title: Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases.

PubMed ID: 16981730

DOI: 10.1021/bi0607498

Sequence Information:

Length: 457
Mass: 50254
Checksum: EBEC85BF907B7FED
Sequence:

MSGTRASNDR PPGTGGVKRG RLQQEAAATG SRVTVVLGAQ WGDEGKGKVV DLLATDADIV 
SRCQGGNNAG HTVVVDGKEY DFHLLPSGII NTKAVSFIGN GVVIHLPGLF EEAEKNEKKG 
LKDWEKRLII SDRAHLVFDF HQAVDGLQEV QRQAQEGKNI GTTKKGIGPT YSSKAARTGL 
RICDLLSDFD EFSARFKNLA HQHQSMFPTL EIDVEGQLKR LKGFAERIRP MVRDGVYFMY 
EALHGPPKKV LVEGANAALL DIDFGTYPFV TSSNCTVGGV CTGLGIPPQN IGDVYGVVKA 
YTTRVGIGAF PTEQINEIGD LLQNRGHEWG VTTGRKRRCG WLDLMILRYA HMVNGFTALA 
LTKLDILDVL SEIKVGISYK LNGKRIPYFP ANQEILQKVE VEYETLPGWK ADTTGARKWE 
DLPPQAQSYV RFVENHMGVA VKWVGVGKSR ESMIQLF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adss1

Associated with

Other Information

Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase. PubMed ID: 1939273

Amplification of an adenylosuccinate synthetase gene in alanosine-resistant murine T-lymphoma cells. Molecular cloning of a cDNA encoding the 'non-muscle' isozyme. PubMed ID: 8308018

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Variations in the response of mouse isozymes of adenylosuccinate synthetase to inhibitors of physiological relevance. PubMed ID: 12482871

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Recombinant mouse muscle adenylosuccinate synthetase: overexpression, kinetics, and crystal structure. PubMed ID: 11560929

IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. PubMed ID: 12004071

Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase. PubMed ID: 12186864

Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases. PubMed ID: 16981730