Genular: Defining Cellular Identity and Function

Details for: Afp

Gene ID: 11576

Symbol: Afp

Ensembl ID: ENSMUSG00000054932

Description: alpha fetoprotein

Associated with

Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Beta-glucuronidase activity
(GO:0004566)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Metal ion binding
(GO:0046872)
Ovulation from ovarian follicle
(GO:0001542)
Progesterone metabolic process
(GO:0042448)
Sexual reproduction
(GO:0019953)
Small molecule binding
(GO:0036094)
Transport
(GO:0006810)

Other Information

Proteins

Alpha-fetoprotein

Genular Protein ID: 3802973480

Symbol: FETA_MOUSE

Name: Alpha-fetoprotein

UniProtKB Accession Codes:

P02772 Q3UJD0

Database IDs:

Citations:

PubMed ID: 6164927

Title: Homology between the primary structure of alpha-fetoprotein, deduced from a complete cDNA sequence, and serum albumin.

PubMed ID: 6164927

DOI: 10.1038/291201a0

PubMed ID: 2452956

Title: The rate of molecular evolution of alpha-fetoprotein approaches that of pseudogenes.

PubMed ID: 2452956

DOI: 10.1093/oxfordjournals.molbev.a040350

PubMed ID: 6172714

Title: Intragenic amplification and divergence in the mouse alpha-fetoprotein gene.

PubMed ID: 6172714

DOI: 10.1038/294713a0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6161929

Title: The evolution of alpha-fetoprotein and albumin. I. A comparison of the primary amino acid sequences of mammalian alpha-fetoprotein and albumin.

PubMed ID: 6161929

DOI: 10.1016/s0021-9258(19)69900-x

Sequence Information:

Length: 605
Mass: 67337
Checksum: CE09E9F50D74619A
Sequence:

MKWITPASLI LLLHFAASKA LHENEFGIAS TLDSSQCVTE KNVLSIATIT FTQFVPEATE 
EEVNKMTSDV LAAMKKNSGD GCLESQLSVF LDEICHETEL SNKYGLSGCC SQSGVERHQC 
LLARKKTAPA SVPPFQFPEP AESCKAHEEN RAVFMNRFIY EVSRRNPFMY APAILSLAAQ 
YDKVVLACCK ADNKEECFQT KRASIAKELR EGSMLNEHVC SVIRKFGSRN LQATTIIKLS 
QKLTEANFTE IQKLALDVAH IHEECCQGNS LECLQDGEKV MTYICSQQNI LSSKIAECCK 
LPMIQLGFCI IHAENGVKPE GLSLNPSQFL GDRNFAQFSS EEKIMFMASF LHEYSRTHPN 
LPVSVILRIA KTYQEILEKC SQSGNLPGCQ DNLEEELQKH IEESQALSKQ SCALYQTLGD 
YKLQNLFLIG YTRKAPQLTS AELIDLTGKM VSIASTCCQL SEEKWSGCGE GMADIFIGHL 
CIRNEASPVN SGISHCCNSS YSNRRLCITS FLRDETYAPP PFSEDKFIFH KDLCQAQGKA 
LQTMKQELLI NLVKQKPELT EEQLAAVTAD FSGLLEKCCK AQDQEVCFTE EGPKLISKTR 
DALGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Afp

Associated with

Other Information

Homology between the primary structure of alpha-fetoprotein, deduced from a complete cDNA sequence, and serum albumin. PubMed ID: 6164927

The rate of molecular evolution of alpha-fetoprotein approaches that of pseudogenes. PubMed ID: 2452956

Intragenic amplification and divergence in the mouse alpha-fetoprotein gene. PubMed ID: 6172714

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334