Details for: Agt

Gene ID: 11606

Symbol: Agt

Ensembl ID: ENSMUSG00000031980

Description: angiotensinogen

Associated with

  • Class a/1 (rhodopsin-like receptors)
    (R-MMU-373076)
  • G alpha (i) signalling events
    (R-MMU-418594)
  • G alpha (q) signalling events
    (R-MMU-416476)
  • Gpcr downstream signalling
    (R-MMU-388396)
  • Gpcr ligand binding
    (R-MMU-500792)
  • Metabolism of angiotensinogen to angiotensins
    (R-MMU-2022377)
  • Metabolism of proteins
    (R-MMU-392499)
  • Peptide hormone metabolism
    (R-MMU-2980736)
  • Peptide ligand-binding receptors
    (R-MMU-375276)
  • Signaling by gpcr
    (R-MMU-372790)
  • Signal transduction
    (R-MMU-162582)
  • Aldosterone secretion
    (GO:0035932)
  • Angiotensin-activated signaling pathway
    (GO:0038166)
  • Angiotensin-mediated drinking behavior
    (GO:0003051)
  • Angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
    (GO:0001998)
  • Artery smooth muscle contraction
    (GO:0014824)
  • Associative learning
    (GO:0008306)
  • Astrocyte activation
    (GO:0048143)
  • Blood vessel development
    (GO:0001568)
  • Brain renin-angiotensin system
    (GO:0002035)
  • Branching involved in ureteric bud morphogenesis
    (GO:0001658)
  • Cell-matrix adhesion
    (GO:0007160)
  • Cell population proliferation
    (GO:0008283)
  • Cell surface receptor signaling pathway
    (GO:0007166)
  • Drinking behavior
    (GO:0042756)
  • Establishment of blood-nerve barrier
    (GO:0008065)
  • Extracellular matrix organization
    (GO:0030198)
  • Fibroblast proliferation
    (GO:0048144)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • Hormone activity
    (GO:0005179)
  • Hormone metabolic process
    (GO:0042445)
  • Intracellular sodium ion homeostasis
    (GO:0006883)
  • Kidney development
    (GO:0001822)
  • Maintenance of blood vessel diameter homeostasis by renin-angiotensin
    (GO:0002034)
  • Mapk cascade
    (GO:0000165)
  • Negative regulation of angiogenesis
    (GO:0016525)
  • Negative regulation of cell growth
    (GO:0030308)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of map kinase activity
    (GO:0043407)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Negative regulation of tissue remodeling
    (GO:0034104)
  • Operant conditioning
    (GO:0035106)
  • Organ growth
    (GO:0035265)
  • Ovarian follicle rupture
    (GO:0001543)
  • Peristalsis
    (GO:0030432)
  • Positive regulation of activation of janus kinase activity
    (GO:0010536)
  • Positive regulation of blood pressure
    (GO:0045777)
  • Positive regulation of canonical nf-kappab signal transduction
    (GO:0043123)
  • Positive regulation of cardiac muscle cell apoptotic process
    (GO:0010666)
  • Positive regulation of cardiac muscle hypertrophy
    (GO:0010613)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of cytokine production
    (GO:0001819)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of endothelial cell migration
    (GO:0010595)
  • Positive regulation of epidermal growth factor receptor signaling pathway
    (GO:0045742)
  • Positive regulation of epithelial to mesenchymal transition
    (GO:0010718)
  • Positive regulation of extracellular matrix constituent secretion
    (GO:0003331)
  • Positive regulation of fatty acid biosynthetic process
    (GO:0045723)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of insulin receptor signaling pathway
    (GO:0046628)
  • Positive regulation of macrophage derived foam cell differentiation
    (GO:0010744)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Positive regulation of multicellular organism growth
    (GO:0040018)
  • Positive regulation of neuron projection development
    (GO:0010976)
  • Positive regulation of nitric oxide biosynthetic process
    (GO:0045429)
  • Positive regulation of organ growth
    (GO:0046622)
  • Positive regulation of peptidyl-serine phosphorylation
    (GO:0033138)
  • Positive regulation of superoxide anion generation
    (GO:0032930)
  • Protein import into nucleus
    (GO:0006606)
  • Receptor ligand activity
    (GO:0048018)
  • Regulation of apoptotic process
    (GO:0042981)
  • Regulation of blood pressure
    (GO:0008217)
  • Regulation of gene expression
    (GO:0010468)
  • Regulation of heart rate
    (GO:0002027)
  • Regulation of norepinephrine secretion
    (GO:0014061)
  • Regulation of renal output by angiotensin
    (GO:0002019)
  • Regulation of systemic arterial blood pressure by circulatory renin-angiotensin
    (GO:0001991)
  • Renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
    (GO:0001999)
  • Renal system process
    (GO:0003014)
  • Renin-angiotensin regulation of aldosterone production
    (GO:0002018)
  • Response to cold
    (GO:0009409)
  • Response to muscle activity involved in regulation of muscle adaptation
    (GO:0014873)
  • Response to salt stress
    (GO:0009651)
  • Sodium channel regulator activity
    (GO:0017080)
  • Type 1 angiotensin receptor binding
    (GO:0031702)
  • Type 2 angiotensin receptor binding
    (GO:0031703)
  • Vasoconstriction
    (GO:0042310)
  • Vasodilation
    (GO:0042311)
  • Vasopressin secretion
    (GO:0030103)

Other Information

Genular Protein ID: 451468801

Symbol: Q3UTR7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UTR7

Database IDs:

AGR 1 ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 21 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 7 MEROPS 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SMART 2 SMR 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 482
  • Mass: 52670
  • Checksum: DC4633B4020178C9
  • Sequence:
    • MHRSEMTPTG AGLKATIFCI LTWVSLTAGD RVYIHPFHLL YHNKSTCAQL ENPSVETLPE 
STFEPVPIQA KTSPVNEKTL HDQLVLAAEK LEDEDRKRAA QVAMIANFVG FRMYKMLNEA 
GSGASGAILS PPALFGTLVS FYLGSLDPTA SQLQTLLDVP VKEGDCTSRL DGHKVLAALR 
AIQGLLVTQG GSSSQTPLLQ SIVVGLFTAP GFRLKHSFVQ SLALFTPALF PRSLDLSTDP 
VLATEKINRF IKAVTGWKMN LPLEGVSTDS TLLFNTYVHF QGTMRGFSQL PGVHEFWVDN 
SISVSVPMIS GTGNFQHWSD TQNNFSVTCV PLGERATLLL IQPHCTSDLD RVEALIFRND 
LLTWIENPPP RAIRLTLPQL EIRGSYNLQD LLAEDKLPTL LGAEANLNNI GDTNPRVGEV 
LNSILLELKA GEEEQPTTSV QQPGSPEALD VTLSSPFLFA IYEQDSGTLH FLGRVNNPQS 
VV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.