Details for: Aif1

Gene ID: 11629

Symbol: Aif1

Ensembl ID: ENSMUSG00000024397

Description: allograft inflammatory factor 1

Associated with

Other Information

Genular Protein ID: 2498266101

Symbol: AIF1_MOUSE

Name: Allograft inflammatory factor 1

UniProtKB Accession Codes:

O70200

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 DisProt 1 EMBL 9 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 45 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 3 SAM 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 11722645

Title: Allograft inflammatory factor-1 augments productions of interleukin-6, -10, -12 by a mouse macrophage line.

PubMed ID: 11722645

DOI: 10.1046/j.1365-2567.2001.01301.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10934045

Title: Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia.

PubMed ID: 10934045

DOI: 10.1242/jcs.113.17.3073

PubMed ID: 11500035

Title: Iba1 is an actin-cross-linking protein in macrophages/microglia.

PubMed ID: 11500035

DOI: 10.1006/bbrc.2001.5388

PubMed ID: 11916959

Title: Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway.

PubMed ID: 11916959

DOI: 10.1074/jbc.m109218200

PubMed ID: 14756805

Title: Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.

PubMed ID: 14756805

DOI: 10.1046/j.1471-4159.2003.02213.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 17011575

Title: X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding.

PubMed ID: 17011575

DOI: 10.1016/j.jmb.2006.09.027

Sequence Information:

  • Length: 147
  • Mass: 16911
  • Checksum: D8974825C153D3CA
  • Sequence:
    • MSQSRDLQGG KAFGLLKAQQ EERLEGINKQ FLDDPKYSND EDLPSKLEAF KVKYMEFDLN 
GNGDIDIMSL KRMLEKLGVP KTHLELKRLI REVSSGSEET FSYSDFLRMM LGKRSAILRM 
ILMYEEKNKE HKRPTGPPAK KAISELP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.