Details for: Aire
Associated with
Other Information
Genular Protein ID: 956961665
Symbol: AIRE_MOUSE
Name: Autoimmune regulator
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10593569
Title: Chromosomal localization and complete genomic sequence of the murine autoimmune regulator gene (Aire).
PubMed ID: 10593569
PubMed ID: 10049735
Title: Isolation and characterization of the mouse Aire gene.
PubMed ID: 10049735
PubMed ID: 10049587
Title: Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome type 1 (ASP1).
PubMed ID: 10049587
PubMed ID: 10022980
Title: The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.
PubMed ID: 10022980
PubMed ID: 10550218
Title: Expression and alternative splicing of the mouse autoimmune regulator gene (Aire).
PubMed ID: 10550218
PubMed ID: 11156688
Title: Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).
PubMed ID: 11156688
PubMed ID: 11533054
Title: The autoimmune regulator (AIRE) is a DNA-binding protein.
PubMed ID: 11533054
PubMed ID: 19015306
Title: Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
PubMed ID: 19015306
DOI: 10.1084/jem.20080046
PubMed ID: 18840680
Title: Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
PubMed ID: 18840680
PubMed ID: 19302042
PubMed ID: 19923453
Title: Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes.
PubMed ID: 19923453
PubMed ID: 21300913
Title: Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.
PubMed ID: 21300913
DOI: 10.1084/jem.20102327
PubMed ID: 23993652
Title: Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4[?] T cells.
PubMed ID: 23993652
PubMed ID: 26070482
Title: Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction.
PubMed ID: 26070482
Sequence Information:
- Length: 552
- Mass: 59042
- Checksum: BF30F8F66B71239A
- Sequence:
MAGGDGMLRR LLRLHRTEIA VAIDSAFPLL HALADHDVVP EDKFQETLRL KEKEGCPQAF HALLSWLLTR DSGAILDFWR ILFKDYNLER YSRLHSILDG FPKDVDLNQS RKGRKPLAGP KAAVLPPRPP TKRKALEEPR ATPPATLASK SVSSPGSHLK TKPPKKPDGN LESQHLPLGN GIQTMAASVQ RAVTVASGDV PGTRGAVEGI LIQQVFESGR SKKCIQVGGE FYTPNKFEDP SGNLKNKARS GSSLKPVVRA KGAQVTIPGR DEQKVGQQCG VPPLPSLPSE PQVNQKNEDE CAVCHDGGEL ICCDGCPRAF HLACLSPPLQ EIPSGLWRCS CCLQGRVQQN LSQPEVSRPP ELPAETPILV GLRSASEKTR GPSRELKASS DAAVTYVNLL APHPAAPLLE PSALCPLLSA GNEGRPGPAP SARCSVCGDG TEVLRCAHCA AAFHWRCHFP TAAARPGTNL RCKSCSADST PTPGTPGEAV PTSGPRPAPG LAKVGDDSAS HDPVLHRDDL ESLLNEHSFD GILQWAIQSM SRPLAETPPF SS
Genular Protein ID: 2331310427
Symbol: Q3ZB65_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 551
- Mass: 58914
- Checksum: 77C75E773B48B72C
- Sequence:
MAGGDGMLRR LLRLHRTEIA VAIDSAFPLL HALADHDVVP EDKFQETLRL KEKEGCPQAF HALLSWLLTR DSGAILDFWR ILFKDYNLER YSRLHSILDG FPKDVDLNQS RKGRKPLAGP KAAVLPPRPP TKRKALEEPR ATPPATLASK SVSSPGSHLK TKPPKKPDGN LESQHLPLGN GIQTMAASVQ RAVTVASGDV PGTRGAVEGI LIQQVFESGR SKKCIQVGGE FYTPNKFEDP SGNLKNKARS GSSLKPVVRA KGAQVTIPGR DEQKVGQQCG VPPLPSLPSE PQVNQNEDEC AVCHDGGELI CCDGCPRAFH LACLSPPLQE IPSGLWRCSC CLQGRVQQNL SQPEVSRPPE LPAETPILVG LRSASEKTRG PSRELKASSD AAVTYVNLLA PHPAAPLLEP SALCPLLSAG NEGRPGPAPS ARCSVCGDGT EVLRCAHCAA AFHWRCHFPT AAARPGTNLR CKSCSADSTP TPGTPGEAVP TSGPRPAPGL AKVGDDSASH DPVLHRDDLE SLLNEHSFDG ILQWAIQSMS RPLAETPPFS S
Genular Protein ID: 99939099
Symbol: Q3ZB71_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 493
- Mass: 52996
- Checksum: 13307FC59268E06E
- Sequence:
MAGGDGMLRR LLRLHRTEIA VAIDSAFPLL HALADHDVVP EDKFQETLRL KEKEGCPQAF HALLSWLLTR DSGAILDFWR ILFKDYNLER YSRLHSILDG FPKDVDLNQS RKGRKPLAGP KAAVLPPRPP TKRKALEEPR ATPPATLASK SVSSPGSHLK TKPPKKPDGN LESQHLPLGN GIQTMAASVQ RAVTVASGDV PGTRGAVEGI LIQQVFESGR SKKCIQVGGE FYTPNKFEDP SGNLKNKARS GSSLKPVVRA KGAQVTIPGR DEQKVGQQCG VPPLPSLPSE PQVNQKNEDE CAVCHDGGEL ICCDGCPRAF HLACLSPPLQ EIPSGLWRCS CCLQGRVQQN LSQPEVSRPP ELPAETPGPA PSARCSVCGD GTEVLRCAHC AAAFHWRCHF PTAAARPGTN LRCKSCSADS TPTPGTPGEA VPTSGPRPAP GLAKVGDDSA SHDPVLHRDD LESLLNEHSF DGILQWAIQS MSRPLAETPP FSS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.