Details for: ADCYAP1R1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 48.6638
Cell Significance Index: -19.7700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3285
Cell Significance Index: 476.5100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.5260
Cell Significance Index: 35.3700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4327
Cell Significance Index: 299.2700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.4220
Cell Significance Index: 9.7500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3651
Cell Significance Index: 73.2400 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 0.3189
Cell Significance Index: 4.4600 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.1534
Cell Significance Index: 1.9900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1210
Cell Significance Index: 7.4400 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.0605
Cell Significance Index: 1.4700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0493
Cell Significance Index: 26.9300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.0066
Cell Significance Index: 0.1400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0043
Cell Significance Index: -8.0800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0154
Cell Significance Index: -0.3700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0168
Cell Significance Index: -0.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0266
Cell Significance Index: -19.7000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0289
Cell Significance Index: -18.3300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0351
Cell Significance Index: -19.7800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0484
Cell Significance Index: -21.9600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0540
Cell Significance Index: -15.5500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0633
Cell Significance Index: -13.3300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0661
Cell Significance Index: -3.4700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0789
Cell Significance Index: -1.5600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1008
Cell Significance Index: -18.1800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.1058
Cell Significance Index: -1.8300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1074
Cell Significance Index: -21.3200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1151
Cell Significance Index: -2.3100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1173
Cell Significance Index: -2.0100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1290
Cell Significance Index: -17.7200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1322
Cell Significance Index: -22.5800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1398
Cell Significance Index: -3.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1454
Cell Significance Index: -18.7800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1463
Cell Significance Index: -21.2600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1579
Cell Significance Index: -19.4200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1816
Cell Significance Index: -18.9100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1954
Cell Significance Index: -22.3900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2018
Cell Significance Index: -20.6100 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.2169
Cell Significance Index: -3.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2172
Cell Significance Index: -7.1100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2286
Cell Significance Index: -7.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2288
Cell Significance Index: -17.5600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2463
Cell Significance Index: -5.1400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2528
Cell Significance Index: -18.8400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2568
Cell Significance Index: -11.3600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2674
Cell Significance Index: -5.8600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3199
Cell Significance Index: -17.9500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3335
Cell Significance Index: -9.3200 - Cell Name: neural cell (CL0002319)
Fold Change: -0.3360
Cell Significance Index: -3.9200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3440
Cell Significance Index: -12.0500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3441
Cell Significance Index: -13.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3700
Cell Significance Index: -17.3900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3771
Cell Significance Index: -19.6400 - Cell Name: neuron (CL0000540)
Fold Change: -0.3882
Cell Significance Index: -3.6800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3942
Cell Significance Index: -11.2500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3998
Cell Significance Index: -11.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.4163
Cell Significance Index: -19.4100 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.4279
Cell Significance Index: -5.4000 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.4360
Cell Significance Index: -4.9900 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.4532
Cell Significance Index: -5.4200 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.4629
Cell Significance Index: -9.1100 - Cell Name: chandelier cell (CL4023083)
Fold Change: -0.4743
Cell Significance Index: -3.8300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4857
Cell Significance Index: -17.8300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.5131
Cell Significance Index: -13.1900 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.5326
Cell Significance Index: -7.3900 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.5612
Cell Significance Index: -5.3400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.5709
Cell Significance Index: -14.2400 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.5832
Cell Significance Index: -11.6300 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.6228
Cell Significance Index: -9.8800 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.6471
Cell Significance Index: -7.0500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6500
Cell Significance Index: -32.8500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.7037
Cell Significance Index: -14.7300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.7320
Cell Significance Index: -19.5500 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.7323
Cell Significance Index: -14.9000 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.7358
Cell Significance Index: -14.3600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7401
Cell Significance Index: -21.8000 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.7430
Cell Significance Index: -18.9300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7493
Cell Significance Index: -30.7000 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.7607
Cell Significance Index: -19.0000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.7659
Cell Significance Index: -20.1400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.7754
Cell Significance Index: -19.3400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.8138
Cell Significance Index: -22.1500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.8162
Cell Significance Index: -21.8700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.8506
Cell Significance Index: -14.2400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.8744
Cell Significance Index: -21.3400 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.8796
Cell Significance Index: -8.8600 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.8834
Cell Significance Index: -38.4100 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.9062
Cell Significance Index: -6.1400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.9164
Cell Significance Index: -13.1600 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.9399
Cell Significance Index: -13.3700 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.9542
Cell Significance Index: -12.7200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.9605
Cell Significance Index: -20.5300 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.9757
Cell Significance Index: -12.7600 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.9873
Cell Significance Index: -15.8400 - Cell Name: mature astrocyte (CL0002627)
Fold Change: -0.9935
Cell Significance Index: -11.0400 - Cell Name: glioblast (CL0000030)
Fold Change: -1.0009
Cell Significance Index: -6.2900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -1.0045
Cell Significance Index: -16.9200 - Cell Name: precursor B cell (CL0000817)
Fold Change: -1.0278
Cell Significance Index: -13.3000 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -1.0328
Cell Significance Index: -14.2800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -1.0409
Cell Significance Index: -12.9100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.0526
Cell Significance Index: -18.6000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2390252204
Symbol: PACR_HUMAN
Name: Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7902709
Title: Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor.
PubMed ID: 7902709
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7851900
Title: Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical and genetic map of chromosome 7.
PubMed ID: 7851900
PubMed ID: 10583729
Title: N-terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants.
PubMed ID: 10583729
PubMed ID: 17470806
Title: Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.
PubMed ID: 17470806
PubMed ID: 21625560
Title: Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors.
PubMed ID: 21625560
Sequence Information:
- Length: 468
- Mass: 53314
- Checksum: BB515B84E9F28977
- Sequence:
MAGVVHVSLA ALLLLPMAPA MHSDCIFKKE QAMCLEKIQR ANELMGFNDS SPGCPGMWDN ITCWKPAHVG EMVLVSCPEL FRIFNPDQVW ETETIGESDF GDSNSLDLSD MGVVSRNCTE DGWSEPFPHY FDACGFDEYE SETGDQDYYY LSVKALYTVG YSTSLVTLTT AMVILCRFRK LHCTRNFIHM NLFVSFMLRA ISVFIKDWIL YAEQDSNHCF ISTVECKAVM VFFHYCVVSN YFWLFIEGLY LFTLLVETFF PERRYFYWYT IIGWGTPTVC VTVWATLRLY FDDTGCWDMN DSTALWWVIK GPVVGSIMVN FVLFIGIIVI LVQKLQSPDM GGNESSIYLR LARSTLLLIP LFGIHYTVFA FSPENVSKRE RLVFELGLGS FQGFVVAVLY CFLNGEVQAE IKRKWRSWKV NRYFAVDFKH RHPSLASSGV NGGTQLSILS KSSSQIRMSG LPADNLAT
Genular Protein ID: 4033488491
Symbol: A0A994J7E9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 12853948
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 495
- Mass: 56444
- Checksum: AE54BAD52C894FA0
- Sequence:
MAGVVHVSLA ALLLLPMAPA MHSDCIFKKE QAMCLEKIQR ANELMGFNDS SPGCPGMWDN ITCWKPAHVG EMVLVSCPEL FRIFNPDQVW ETETIGESDF GDSNSLDLSD MGVVSRNCTE DGWSEPFPHY FDACGFDEYE SETGDQDYYY LSVKALYTVG YSTSLVTLTT AMVILCRFRK LHCTRNFIHM NLFVSFMLRA ISVFIKDWIL YAEQDSNHCF ISTVECKAVM VFFHYCVVSN YFWLFIEGLY LFTLLVETFF PERRYFYWYT IIGWGTPTVC VTVWATLRLY FDDTGCWDMN DSTALWWVIK GPVVGSIMVN FVLFIGIIVI LVQKLQSPDM GGNESSIYFC VQKCYCKPQR AQQHSCKMSE LSTITLRLAR STLLLIPLFG IHYTVFAFSP ENVSKRERLV FELGLGSFQG FVVAVLYCFL NGEVQAEIKR KWRSWKVNRY FAVDFKHRHP SLASSGVNGG TQLSILSKSS SQIRMSGLPA DNLAT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.