Genular: Defining Cellular Identity and Function

Details for: Ang

Gene ID: 11727

Symbol: Ang

Ensembl ID: ENSMUSG00000072115

Description: angiogenin, ribonuclease, RNase A family, 5

Associated with

Adherens junctions interactions
(R-MMU-418990)
Cell-cell communication
(R-MMU-1500931)
Cell-cell junction organization
(R-MMU-421270)
Cell junction organization
(R-MMU-446728)
Actin binding
(GO:0003779)
Actin cytoskeleton
(GO:0015629)
Activation of phospholipase a2 activity
(GO:0032431)
Activation of phospholipase c activity
(GO:0007202)
Activation of protein kinase b activity
(GO:0032148)
Angiogenesis
(GO:0001525)
Angiogenin-pri complex
(GO:0032311)
Antibacterial humoral response
(GO:0019731)
Antifungal humoral response
(GO:0019732)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Basement membrane
(GO:0005604)
Cell differentiation
(GO:0030154)
Cell migration
(GO:0016477)
Central nervous system development
(GO:0007417)
Chromosome
(GO:0005694)
Copper ion binding
(GO:0005507)
Cytoplasmic vesicle
(GO:0031410)
Defense response to gram-positive bacterium
(GO:0050830)
Diacylglycerol biosynthetic process
(GO:0006651)
Dna binding
(GO:0003677)
Endonuclease activity
(GO:0004519)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth cone
(GO:0030426)
Heparin binding
(GO:0008201)
Hydrolase activity
(GO:0016787)
Innate immune response
(GO:0045087)
Multicellular organism development
(GO:0007275)
Negative regulation of smooth muscle cell proliferation
(GO:0048662)
Negative regulation of translation
(GO:0017148)
Neuronal cell body
(GO:0043025)
Nuclease activity
(GO:0004518)
Nucleic acid binding
(GO:0003676)
Nucleolus
(GO:0005730)
Nucleus
(GO:0005634)
Peptide binding
(GO:0042277)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of phosphorylation
(GO:0042327)
Positive regulation of protein secretion
(GO:0050714)
Protein homodimerization activity
(GO:0042803)
Response to hormone
(GO:0009725)
Response to hypoxia
(GO:0001666)
Response to yeast
(GO:0001878)
Rna binding
(GO:0003723)
Rna nuclease activity
(GO:0004540)
Rrna transcription
(GO:0009303)
Signaling receptor binding
(GO:0005102)
Trna-specific ribonuclease activity
(GO:0004549)
Trna destabilization
(GO:0036417)

Other Information

Proteins

Angiogenin

Genular Protein ID: 3711024988

Symbol: ANGI_MOUSE

Name: Angiogenin

UniProtKB Accession Codes:

P21570

Database IDs:

Citations:

PubMed ID: 2222458

Title: Isolation and sequencing of mouse angiogenin DNA.

PubMed ID: 2222458

DOI: 10.1016/0006-291x(90)90781-h

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8448182

Title: Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions.

PubMed ID: 8448182

DOI: 10.1016/0167-4838(93)90145-h

PubMed ID: 19114040

Title: Stress induces tRNA cleavage by angiogenin in mammalian cells.

PubMed ID: 19114040

DOI: 10.1016/j.febslet.2008.12.043

PubMed ID: 33986151

Title: SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity.

PubMed ID: 33986151

DOI: 10.1126/science.aba4220

PubMed ID: 16301790

Title: Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies.

PubMed ID: 16301790

DOI: 10.1107/s0907444905029616

Sequence Information:

Length: 145
Mass: 16228
Checksum: 06944260BB764938
Sequence:

MAISPGPLFL IFVLGLVVIP PTLAQDDSRY TKFLTQHHDA KPKGRDDRYC ERMMKRRSLT 
SPCKDVNTFI HGNKSNIKAI CGANGSPYRE NLRMSKSPFQ VTTCKHTGGS PRPPCQYRAS 
AGFRHVVIAC ENGLPVHFDE SFFSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ang

Associated with

Other Information

Isolation and sequencing of mouse angiogenin DNA. PubMed ID: 2222458

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions. PubMed ID: 8448182

Stress induces tRNA cleavage by angiogenin in mammalian cells. PubMed ID: 19114040

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity. PubMed ID: 33986151