AP1S1 | ENSG00000106367 | NCBI 1174

Details for: AP1S1

Gene ID: 1174

Symbol: AP1S1

Ensembl ID: ENSG00000106367

Description: adaptor related protein complex 1 subunit sigma 1

Associated with

Adaptive immune system
(R-HSA-1280218)
Disease
(R-HSA-1643685)
Golgi associated vesicle biogenesis
(R-HSA-432722)
Hiv infection
(R-HSA-162906)
Host interactions of hiv factors
(R-HSA-162909)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Lysosome vesicle biogenesis
(R-HSA-432720)
Membrane trafficking
(R-HSA-199991)
Mhc class ii antigen presentation
(R-HSA-2132295)
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
(R-HSA-164938)
Nef mediated downregulation of mhc class i complex cell surface expression
(R-HSA-164940)
The role of nef in hiv-1 replication and disease pathogenesis
(R-HSA-164952)
Trans-golgi network vesicle budding
(R-HSA-199992)
Viral infection pathways
(R-HSA-9824446)
Ap-1 adaptor complex
(GO:0030121)
Basolateral protein secretion
(GO:0110010)
Clathrin-coated pit
(GO:0005905)
Clathrin adaptor activity
(GO:0035615)
Cytoplasmic vesicle membrane
(GO:0030659)
Cytosol
(GO:0005829)
Early endosome
(GO:0005769)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Intracellular membrane-bounded organelle
(GO:0043231)
Intracellular protein transport
(GO:0006886)
Lysosomal membrane
(GO:0005765)
Melanosome assembly
(GO:1903232)
Membrane
(GO:0016020)
Platelet dense granule organization
(GO:0060155)
Receptor-mediated endocytosis
(GO:0006898)
Response to virus
(GO:0009615)
Trans-golgi network membrane
(GO:0032588)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

AP-1 complex subunit sigma-1A

Genular Protein ID: 166606752

Symbol: AP1S1_HUMAN

Name: AP-1 complex subunit sigma-1A

UniProtKB Accession Codes:

P61966 B2R5D8 P82267 Q00382 Q53YA7 Q9BTN4 Q9UDW9

Database IDs:

Citations:

PubMed ID: 9733768

Title: Identification and characterization of novel clathrin adaptor-related proteins.

PubMed ID: 9733768

DOI: 10.1074/jbc.273.38.24693

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16548883

Title: Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

PubMed ID: 16548883

DOI: 10.1111/j.1462-5822.2005.00644.x

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19057675

Title: Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord.

PubMed ID: 19057675

DOI: 10.1371/journal.pgen.1000296

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 158
Mass: 18733
Checksum: E461937790406D8B
Sequence:

MMRFMLLFSR QGKLRLQKWY LATSDKERKK MVRELMQVVL ARKPKMCSFL EWRDLKVVYK 
RYASLYFCCA IEGQDNELIT LELIHRYVEL LDKYFGSVCE LDIIFNFEKA YFILDEFLMG 
GDVQDTSKKS VLKAIEQADL LQEEDESPRS VLEEMGLA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AP1S1

Associated with

Other Information

Identification and characterization of novel clathrin adaptor-related proteins. PubMed ID: 9733768

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection. PubMed ID: 16548883

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord. PubMed ID: 19057675

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569