Details for: AP2S1

Gene ID: 1175

Symbol: AP2S1

Ensembl ID: ENSG00000042753

Description: adaptor related protein complex 2 subunit sigma 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 240.3160
    Cell Significance Index: -37.3800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 223.2662
    Cell Significance Index: -56.6300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 182.6082
    Cell Significance Index: -75.2300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 166.2863
    Cell Significance Index: -67.5600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 158.4440
    Cell Significance Index: -74.8100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 143.3556
    Cell Significance Index: -73.7400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 111.7623
    Cell Significance Index: -75.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 71.5638
    Cell Significance Index: -68.3300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.9426
    Cell Significance Index: -62.8100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.8252
    Cell Significance Index: -50.4300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.7225
    Cell Significance Index: -73.8800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.2785
    Cell Significance Index: -53.0700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.3354
    Cell Significance Index: -22.6200
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 6.4995
    Cell Significance Index: 55.8500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.1812
    Cell Significance Index: 77.2800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 3.1025
    Cell Significance Index: 26.0600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.9364
    Cell Significance Index: 136.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.6885
    Cell Significance Index: 1468.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.4336
    Cell Significance Index: 63.9900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.3797
    Cell Significance Index: 49.8100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.2851
    Cell Significance Index: 67.1100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.0426
    Cell Significance Index: 96.0000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.8225
    Cell Significance Index: 16.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.8039
    Cell Significance Index: 221.8100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.7873
    Cell Significance Index: 93.8400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7306
    Cell Significance Index: 311.9800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.5616
    Cell Significance Index: 214.4500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.5272
    Cell Significance Index: 17.3500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.4910
    Cell Significance Index: 175.8300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.3670
    Cell Significance Index: 96.6800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3623
    Cell Significance Index: 602.2900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.3278
    Cell Significance Index: 171.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.2993
    Cell Significance Index: 83.8300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.2011
    Cell Significance Index: 89.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.9437
    Cell Significance Index: 14.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8230
    Cell Significance Index: 105.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7541
    Cell Significance Index: 34.1800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.7045
    Cell Significance Index: 5.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.6842
    Cell Significance Index: 18.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6410
    Cell Significance Index: 33.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5876
    Cell Significance Index: 12.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5864
    Cell Significance Index: 529.5000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5737
    Cell Significance Index: 115.0900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.5675
    Cell Significance Index: 6.1700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5350
    Cell Significance Index: 18.5900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4302
    Cell Significance Index: 42.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4051
    Cell Significance Index: 80.4000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3597
    Cell Significance Index: 8.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3539
    Cell Significance Index: 38.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3304
    Cell Significance Index: 62.8700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2205
    Cell Significance Index: 6.3200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2053
    Cell Significance Index: 33.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1990
    Cell Significance Index: 10.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1355
    Cell Significance Index: 48.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0844
    Cell Significance Index: 63.8600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0414
    Cell Significance Index: 0.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0287
    Cell Significance Index: 0.4800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0269
    Cell Significance Index: 19.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0127
    Cell Significance Index: 0.4500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0016
    Cell Significance Index: 0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0289
    Cell Significance Index: -54.4400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0468
    Cell Significance Index: -86.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0567
    Cell Significance Index: -87.3600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0666
    Cell Significance Index: -90.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0706
    Cell Significance Index: -52.2900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0713
    Cell Significance Index: -49.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0837
    Cell Significance Index: -14.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0981
    Cell Significance Index: -62.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1186
    Cell Significance Index: -66.8900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1316
    Cell Significance Index: -82.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1332
    Cell Significance Index: -60.4500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1682
    Cell Significance Index: -4.7000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2155
    Cell Significance Index: -62.0000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2926
    Cell Significance Index: -9.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3228
    Cell Significance Index: -37.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.3285
    Cell Significance Index: -19.7200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3370
    Cell Significance Index: -8.6100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3937
    Cell Significance Index: -82.9200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4449
    Cell Significance Index: -50.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4739
    Cell Significance Index: -68.8900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4783
    Cell Significance Index: -12.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4853
    Cell Significance Index: -29.8300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.5034
    Cell Significance Index: -8.9000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.5185
    Cell Significance Index: -6.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5614
    Cell Significance Index: -15.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6263
    Cell Significance Index: -49.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6321
    Cell Significance Index: -39.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6359
    Cell Significance Index: -42.7600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6946
    Cell Significance Index: -72.3200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.7604
    Cell Significance Index: -10.3800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8131
    Cell Significance Index: -62.4000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.8628
    Cell Significance Index: -5.3100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.8666
    Cell Significance Index: -23.2200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.8998
    Cell Significance Index: -26.5000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9703
    Cell Significance Index: -59.4900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.0623
    Cell Significance Index: -59.6100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.0954
    Cell Significance Index: -11.3400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.3006
    Cell Significance Index: -27.7000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -1.3870
    Cell Significance Index: -11.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.4657
    Cell Significance Index: -64.8300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AP2S1 is a 63-kDa subunit of the AP-2 complex, which is a heterotetrameric protein complex composed of two alpha, two beta, and one sigma subunits. The sigma subunit (AP2S1) is responsible for binding to the adaptor protein-2 complex and facilitating the interaction with target proteins. AP2S1 is characterized by its ability to interact with various proteins, including clathrin, receptor tyrosine kinases, and Wnt proteins, which are involved in signaling pathways. **Pathways and Functions:** AP2S1 is involved in various cellular processes, including: 1. **Endocytosis:** AP2S1 plays a crucial role in clathrin-mediated endocytosis, which is essential for the internalization of receptors, ligands, and other molecules. 2. **Signaling:** AP2S1 interacts with receptor tyrosine kinases, Wnt proteins, and other signaling molecules, regulating downstream signaling pathways, including those involved in immune function and cellular development. 3. **Immune Function:** AP2S1 is expressed in immune cells, including macrophages, monocytes, and T cells, where it regulates the internalization and degradation of pathogens, antigens, and other molecules. 4. **Neurotransmission:** AP2S1 interacts with neurotransmitter receptors, regulating synaptic plasticity and neurotransmitter release. 5. **Viral Infection:** AP2S1 is involved in the internalization and degradation of viral proteins, regulating the replication and pathogenesis of HIV-1. **Clinical Significance:** Dysregulation of AP2S1 has been implicated in various diseases, including: 1. **HIV-1 Infection:** AP2S1 is involved in the internalization and degradation of HIV-1 proteins, regulating the replication and pathogenesis of the virus. 2. **Cancer:** AP2S1 is overexpressed in certain types of cancer, including breast and lung cancer, where it regulates cell growth, invasion, and metastasis. 3. **Neurodegenerative Diseases:** AP2S1 is involved in the regulation of synaptic plasticity and neurotransmission in neurodegenerative diseases, including Alzheimer's and Parkinson's disease. 4. **Infectious Diseases:** AP2S1 is involved in the regulation of immune responses to infectious diseases, including those caused by viruses, bacteria, and parasites. In conclusion, AP2S1 is a crucial component of the AP-2 complex, involved in various cellular processes, including endocytosis, signaling, and immune function. Dysregulation of AP2S1 has been implicated in various diseases, highlighting the importance of this protein in maintaining cellular homeostasis and regulating disease pathogenesis.

Genular Protein ID: 2507034195

Symbol: AP2S1_HUMAN

Name: AP-2 complex subunit sigma

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9040778

Title: Human CLAPS2 encoding AP17, a small chain of the clathrin-associated protein complex: cDNA cloning and chromosomal assignment to 19q13.2-->q13.3.

PubMed ID: 9040778

DOI: 10.1159/000134463

PubMed ID: 9767099

Title: A novel spliced transcript of human CLAPS2 encoding a protein alternative to clathrin adaptor protein AP17.

PubMed ID: 9767099

DOI: 10.1016/s0378-1119(98)00406-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14745134

Title: Adaptor protein complexes as the key regulators of protein sorting in the post-Golgi network.

PubMed ID: 14745134

DOI: 10.1247/csf.28.419

PubMed ID: 15473838

Title: Adaptors for clathrin coats: structure and function.

PubMed ID: 15473838

DOI: 10.1146/annurev.cellbio.20.010403.104543

PubMed ID: 19033387

Title: The adaptor complex AP-2 regulates post-endocytic trafficking through the non-clathrin Arf6-dependent endocytic pathway.

PubMed ID: 19033387

DOI: 10.1242/jcs.033522

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23222959

Title: Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

PubMed ID: 23222959

DOI: 10.1038/ng.2492

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 33859415

Title: A genome-wide atlas of co-essential modules assigns function to uncharacterized genes.

PubMed ID: 33859415

DOI: 10.1038/s41588-021-00840-z

PubMed ID: 24081735

Title: Identification of AP2S1 mutation and effects of low calcium formula in an infant with hypercalcemia and hypercalciuria.

PubMed ID: 24081735

DOI: 10.1210/jc.2013-2571

Sequence Information:

  • Length: 142
  • Mass: 17018
  • Checksum: CA3FD868C65AEDF6
  • Sequence:
  • MIRFILIQNR AGKTRLAKWY MQFDDDEKQK LIEEVHAVVT VRDAKHTNFV EFRNFKIIYR 
    RYAGLYFCIC VDVNDNNLAY LEAIHNFVEV LNEYFHNVCE LDLVFNFYKV YTVVDEMFLA 
    GEIRETSQTK VLKQLLMLQS LE

Genular Protein ID: 3944296357

Symbol: M0R0N4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 144
  • Mass: 17303
  • Checksum: DC3C494873F879A5
  • Sequence:
  • MVWIRFILIQ NRAGKTRLAK WYMQFDDDEK QKLIEEVHAV VTVRDAKHTN FVEFRNFKII 
    YRRYAGLYFC ICVDVNDNNL AYLEAIHNFV EVLNEYFHNV CELDLVFNFY KVYTVVDEMF 
    LAGEIRETSQ TKVLKQLLML QSLE

Genular Protein ID: 2145304583

Symbol: M0QYZ2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 158
  • Mass: 18929
  • Checksum: 685BDAF358F5893D
  • Sequence:
  • MKLKGLGKRC KRREDLEIRF ILIQNRAGKT RLAKWYMQFD DDEKQKLIEE VHAVVTVRDA 
    KHTNFVEFRN FKIIYRRYAG LYFCICVDVN DNNLAYLEAI HNFVEVLNEY FHNVCELDLV 
    FNFYKVYTVV DEMFLAGEIR ETSQTKVLKQ LLMLQSLE

Genular Protein ID: 1402327176

Symbol: X6R390_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 156
  • Mass: 18414
  • Checksum: 068FA6AE5AC56109
  • Sequence:
  • MIRFILIQNR AGKTRLAKWY MQFDDDEKQK LIEEVHAVVT VRDAKHTNFV EVLAISVADS 
    LSVLQFRNFK IIYRRYAGLY FCICVDVNDN NLAYLEAIHN FVEVLNEYFH NVCELDLVFN 
    FYKVYTVVDE MFLAGEIRET SQTKVLKQLL MLQSLE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.