Details for: Atg5

Gene ID: 11793

Symbol: Atg5

Ensembl ID: ENSMUSG00000038160

Description: autophagy related 5

Associated with

Other Information

Genular Protein ID: 3259684416

Symbol: ATG5_MOUSE

Name: Autophagy protein 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11266458

Title: Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.

PubMed ID: 11266458

DOI: 10.1083/jcb.152.4.657

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12482611

Title: Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method.

PubMed ID: 12482611

DOI: 10.1016/s0014-5793(02)03739-0

PubMed ID: 12890687

Title: The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.

PubMed ID: 12890687

DOI: 10.1074/jbc.m300550200

PubMed ID: 12665549

Title: Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.

PubMed ID: 12665549

DOI: 10.1242/jcs.00381

PubMed ID: 17912025

Title: Aberrant membranes and double-membrane structures accumulate in the axons of Atg5-null Purkinje cells before neuronal death.

PubMed ID: 17912025

DOI: 10.4161/auto.4964

PubMed ID: 17190837

Title: A critical role for the autophagy gene Atg5 in T cell survival and proliferation.

PubMed ID: 17190837

DOI: 10.1084/jem.20061303

PubMed ID: 17709747

Title: The Atg5-Atg12 conjugate associates with innate antiviral immune responses.

PubMed ID: 17709747

DOI: 10.1073/pnas.0704014104

PubMed ID: 18188005

Title: The autophagy gene ATG5 plays an essential role in B lymphocyte development.

PubMed ID: 18188005

DOI: 10.4161/auto.5474

PubMed ID: 18768753

Title: The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.

PubMed ID: 18768753

DOI: 10.1091/mbc.e08-03-0309

PubMed ID: 19417210

Title: Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation.

PubMed ID: 19417210

DOI: 10.1182/blood-2008-04-151639

PubMed ID: 19844159

Title: Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice.

PubMed ID: 19844159

DOI: 10.4161/auto.5.8.9991

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20171125

Title: In vivo requirement for Atg5 in antigen presentation by dendritic cells.

PubMed ID: 20171125

DOI: 10.1016/j.immuni.2009.12.006

PubMed ID: 24089209

Title: Functional interaction between autophagy and ciliogenesis.

PubMed ID: 24089209

DOI: 10.1038/nature12639

PubMed ID: 24089205

Title: Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.

PubMed ID: 24089205

DOI: 10.1038/nature12606

PubMed ID: 28231469

Title: Bassoon Controls Presynaptic Autophagy through Atg5.

PubMed ID: 28231469

DOI: 10.1016/j.neuron.2017.01.026

PubMed ID: 22082872

Title: Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12-5-16L2 complex.

PubMed ID: 22082872

DOI: 10.4161/auto.7.12.18025

Sequence Information:

  • Length: 275
  • Mass: 32402
  • Checksum: F3FCE652D627B694
  • Sequence:
  • MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM 
    RQEDVSEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA 
    VEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPPEEN 
    GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLR EVCPSAVAPE DGEKRSQVMI 
    HGIEPMLETP LQWLSEHLSY PDNFLHISIV PQPTD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.