Genular: Defining Cellular Identity and Function

Details for: Birc5

Gene ID: 11799

Symbol: Birc5

Ensembl ID: ENSMUSG00000017716

Description: baculoviral IAP repeat-containing 5

Associated with

Apical plasma membrane
(GO:0016324)
Apoptotic process
(GO:0006915)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Centriole
(GO:0005814)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome passenger complex
(GO:0032133)
Chromosome segregation
(GO:0007059)
Cysteine-type endopeptidase inhibitor activity
(GO:0004869)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Cytoplasm
(GO:0005737)
Cytoplasmic microtubule
(GO:0005881)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Embryo development
(GO:0009790)
Enzyme binding
(GO:0019899)
Establishment of chromosome localization
(GO:0051303)
G2/m transition of mitotic cell cycle
(GO:0000086)
Identical protein binding
(GO:0042802)
Interphase microtubule organizing center
(GO:0031021)
Kinetochore
(GO:0000776)
Meiosis i
(GO:0007127)
Metal ion binding
(GO:0046872)
Microtubule
(GO:0005874)
Microtubule binding
(GO:0008017)
Microtubule cytoskeleton
(GO:0015630)
Microtubule cytoskeleton organization
(GO:0000226)
Midbody
(GO:0030496)
Mitotic cell cycle
(GO:0000278)
Mitotic cytokinesis
(GO:0000281)
Mitotic spindle assembly checkpoint signaling
(GO:0007094)
Mitotic spindle midzone assembly
(GO:0051256)
Mitotic spindle organization
(GO:0007052)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043154)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of peptidase activity
(GO:0010466)
Nuclear chromosome
(GO:0000228)
Nucleus
(GO:0005634)
Peptidase inhibitor activity
(GO:0030414)
Positive regulation of attachment of mitotic spindle microtubules to kinetochore
(GO:1902425)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of exit from mitosis
(GO:0031536)
Positive regulation of mitotic cell cycle
(GO:0045931)
Positive regulation of mitotic cell cycle spindle assembly checkpoint
(GO:0090267)
Positive regulation of mitotic cytokinesis
(GO:1903490)
Positive regulation of mitotic sister chromatid separation
(GO:1901970)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein ubiquitination
(GO:0031398)
Protein-containing complex
(GO:0032991)
Protein-containing complex localization
(GO:0031503)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Protein phosphorylation
(GO:0006468)
Regulation of cell cycle
(GO:0051726)
Regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0061178)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of type b pancreatic cell proliferation
(GO:0061469)
Small gtpase binding
(GO:0031267)
Spindle microtubule
(GO:0005876)
Survivin complex
(GO:1990713)
Tubulin binding
(GO:0015631)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Baculoviral IAP repeat-containing protein 5

Genular Protein ID: 3559646683

Symbol: BIRC5_MOUSE

Name: Baculoviral IAP repeat-containing protein 5

UniProtKB Accession Codes:

O70201 Q923F7 Q9WU53 Q9WU54

Database IDs:

Citations:

PubMed ID: 10666222

Title: Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions.

PubMed ID: 10666222

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 25778398

Title: The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin.

PubMed ID: 25778398

DOI: 10.1074/jbc.m114.629931

PubMed ID: 10949038

Title: Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin.

PubMed ID: 10949038

DOI: 10.1016/s1097-2765(05)00019-5

Sequence Information:

Length: 140
Mass: 16298
Checksum: 26F5ABF501A6D83C
Sequence:

MGAPALPQIW QLYLKNYRIA TFKNWPFLED CACTPERMAE AGFIHCPTEN EPDLAQCFFC 
FKELEGWEPD DNPIEEHRKH SPGCAFLTVK KQMEELTVSE FLKLDRQRAK NKIAKETNNK 
QKEFEETAKT TRQSIEQLAA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Birc5

Associated with

Other Information

Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions. PubMed ID: 10666222

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. PubMed ID: 25778398

Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin. PubMed ID: 10949038

Database document:

PubMed ID: 10666222

PubMed ID: 15489334

PubMed ID: 25778398

PubMed ID: 10949038